FR3107708B1 - Microalgue recombinante capable de produire des peptides, polypeptides et protéines de KTTKS et leurs dérivés, et leurs procédé et utilisations associés - Google Patents

Microalgue recombinante capable de produire des peptides, polypeptides et protéines de KTTKS et leurs dérivés, et leurs procédé et utilisations associés Download PDF

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Publication number
FR3107708B1
FR3107708B1 FR2002027A FR2002027A FR3107708B1 FR 3107708 B1 FR3107708 B1 FR 3107708B1 FR 2002027 A FR2002027 A FR 2002027A FR 2002027 A FR2002027 A FR 2002027A FR 3107708 B1 FR3107708 B1 FR 3107708B1
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France
Prior art keywords
recombinant
polypeptides
kttks
proteins
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR2002027A
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English (en)
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FR3107708A1 (fr
Inventor
Ghislaine Tissot-Lecuelle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sederma SA
Alganelle SAS
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Sederma SA
Alganelle SAS
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Publication date
Application filed by Sederma SA, Alganelle SAS filed Critical Sederma SA
Priority to FR2002027A priority Critical patent/FR3107708B1/fr
Priority to CN202180017129.1A priority patent/CN115551884A/zh
Priority to PCT/EP2021/054749 priority patent/WO2021170754A1/fr
Priority to US17/802,572 priority patent/US20240051994A2/en
Priority to EP21709902.7A priority patent/EP4110806A1/fr
Publication of FR3107708A1 publication Critical patent/FR3107708A1/fr
Application granted granted Critical
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Hematology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Microalgue recombinante capable de produire des peptides, polypeptides o u protéines de KTTKS et leurs dérivés , et leurs procédé et utilisations associés La présente invention concerne une microalgue recombinante comprenant une séquence d’acides nucléiques codant un peptide recombinant de KTTKS (SEQ ID N°1) ; un peptide, polypeptide ou protéine recombinant constitué d’unités répétées de SEQ ID N°1 ; ou un dérivé de ceux-ci, ladite séquence d’acides nucléiques étant située dans le génome chloroplastique de la microalgue. Elle concerne également un procédé de production d'un peptide recombinant de SEQ ID N°1 ; un peptide, polypeptide ou protéine recombinant consistant en des unités répétées de SEQ ID N°1 ; ou un dérivé de ceux-ci, dans lequel ledit procédé comprend la transformation du génome chloroplastique d'une microalgue avec une séquence d’acides nucléiques codant ladite protéine, polypeptide ou peptide recombinant. Elle concerne en outre l'utilisation desdits peptides, polypeptides ou protéines recombinants dans l'industrie cosmétique. Figure pour l’abrégé : pas de figure
FR2002027A 2020-02-28 2020-02-28 Microalgue recombinante capable de produire des peptides, polypeptides et protéines de KTTKS et leurs dérivés, et leurs procédé et utilisations associés Active FR3107708B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR2002027A FR3107708B1 (fr) 2020-02-28 2020-02-28 Microalgue recombinante capable de produire des peptides, polypeptides et protéines de KTTKS et leurs dérivés, et leurs procédé et utilisations associés
CN202180017129.1A CN115551884A (zh) 2020-02-28 2021-02-25 能产生kttks肽、多肽或蛋白和它们的衍生物的重组微藻以及其相关方法和用途
PCT/EP2021/054749 WO2021170754A1 (fr) 2020-02-28 2021-02-25 Micro-algues recombinantes capables de produire des peptides, des polypeptides ou des protéines kttks et leurs dérivés, et procédé et utilisations associés
US17/802,572 US20240051994A2 (en) 2020-02-28 2021-02-25 Recombinant microalgae able to produce kttks peptides, polypeptides, or proteins and their derivatives and associated method and uses thereof
EP21709902.7A EP4110806A1 (fr) 2020-02-28 2021-02-25 Micro-algues recombinantes capables de produire des peptides, des polypeptides ou des protéines kttks et leurs dérivés, et procédé et utilisations associés

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2002027 2020-02-28
FR2002027A FR3107708B1 (fr) 2020-02-28 2020-02-28 Microalgue recombinante capable de produire des peptides, polypeptides et protéines de KTTKS et leurs dérivés, et leurs procédé et utilisations associés

Publications (2)

Publication Number Publication Date
FR3107708A1 FR3107708A1 (fr) 2021-09-03
FR3107708B1 true FR3107708B1 (fr) 2025-03-07

Family

ID=71661970

Family Applications (1)

Application Number Title Priority Date Filing Date
FR2002027A Active FR3107708B1 (fr) 2020-02-28 2020-02-28 Microalgue recombinante capable de produire des peptides, polypeptides et protéines de KTTKS et leurs dérivés, et leurs procédé et utilisations associés

Country Status (5)

Country Link
US (1) US20240051994A2 (fr)
EP (1) EP4110806A1 (fr)
CN (1) CN115551884A (fr)
FR (1) FR3107708B1 (fr)
WO (1) WO2021170754A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023198774A1 (fr) 2022-04-14 2023-10-19 Institute Of Agricultural Resources And Regional Planning Of The Chinese Academy Of Agricultural Sciences Microalgues modifiées pour une meilleure absorption de phosphate impliquant la surexpression de psr1 et éventuellement la sous-expression de ptc1
CN119143848B (zh) * 2023-12-26 2025-11-25 杭州湃肽生化科技有限公司 环七肽-4及其制备方法及应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2668365B1 (fr) 1990-10-25 1994-12-23 Sederma Sa Utilisation en cosmetique des n-acetylpeptides dotes d'une activite biologique.
FR2735687B1 (fr) 1995-06-21 1997-08-14 Sederma Sa Nouvelles compositions cosmetiques amincissantes
WO1998007744A1 (fr) 1996-08-23 1998-02-26 Sederma S.A. Peptides synthetiques et leur utilisation dans les compositions cosmetiques ou dermopharmaceutiques
FR2783169B1 (fr) * 1998-09-15 2001-11-02 Sederma Sa Utilisation cosmetique ou dermopharmaceutique de peptides pour la cicatrisation et pour l'amelioration de l'aspect cutane lors du vieillissement naturel ou accelere (heliodermie, pollution)
FR2788058B1 (fr) 1998-12-30 2002-01-25 Sederma Sa Compositions cosmetiques amincissantes
FR2788777B1 (fr) 1999-01-22 2003-01-17 Sederma Sa Utilisation cosmetique ou dermopharmaceutique de peptides pour la regulation des dysfonctionnements immunologiques cutanes et dans l'inflammation cutanee induits par le vieillissement ou par les u.v.
FR2791684B1 (fr) 1999-03-30 2001-05-11 Sederma Sa Composition cosmetiques ou dermopharmaceutiques contenant le tripeptide n-n-biotinyl-gly-his-lys pour prevenir, reduire ou supprimer la chute des cheveux ainsi que pour favoriser leur repousse
FR2802413B1 (fr) 1999-12-17 2003-10-31 Sederma Sa Compositions cosmetiques ou dermopharmaceutiques contenant le tripeptide n-palmytoyl-gly-hys-lys, pour eliminer, reduire ou prevenir l'apparition de rides quelles qu'en soient la localisation et la cause
FR2805744B1 (fr) 2000-03-03 2006-08-25 Sederma Sa Compositions cosmetiques ou dermopharmaceutiques contenant le dipeptide val-trp pour faciliter le drainage lymphatique et diminuer la masse adipeuse
FR2836042B1 (fr) 2002-02-15 2004-04-02 Sederma Sa Compositions cosmetiques ou dermopharmaceutiques pour diminuer les poches et cernes sous les yeux
JP4256389B2 (ja) 2003-11-17 2009-04-22 セダーマ テトラペプチドとトリペプチドの混合物を含む組成物
FR2869229B1 (fr) 2004-04-26 2006-08-25 Sederma Soc Par Actions Simpli Utilisation d'un inducteur des ugt par voie topique
WO2006114657A1 (fr) 2005-04-27 2006-11-02 Sederma Dipeptides lys-thr et leur utilisation
EP1960421B1 (fr) 2005-12-15 2013-03-13 Sederma Nouveaux polypeptides et leur utilisation
EP1984387B1 (fr) 2006-02-16 2017-05-31 Sederma Polypeptides kxk et leurs applications
FR2900573B1 (fr) 2006-05-05 2014-05-16 Sederma Sa Nouvelles compositions cosmetiques renfermant au moins un peptide contenant au moins un cycle aromatique bloque
WO2007133558A2 (fr) * 2006-05-09 2007-11-22 The Scripps Research Institute Expression vigoureuse d'une protéine mammalienne bioactive dans des chloroplastes de chlamydomonas
US20100089287A1 (en) 2008-09-25 2010-04-15 Thames Shelby F Soy protein adhesive and uses thereof
EP2348019A4 (fr) 2008-10-29 2012-10-31 Kowa Co Dérivé 1,2-diazétidin-3-one et agent pharmaceutique le comprenant
US8195215B2 (en) 2008-12-18 2012-06-05 Motorola Solutions, Inc. Method and system for forming a communication group for content distribution related to an event
FR2941231B1 (fr) 2009-01-16 2016-04-01 Sederma Sa Nouveaux peptides, compositions les comprenant et utilisations cosmetiques et dermo-pharmaceutiques.
EP3744729B1 (fr) 2009-01-16 2023-03-01 Sederma Peptides, compositions comprenant ces derniers et leurs utilisations dans les domaines cosmétique et dermopharmaceutique
FR2945939B1 (fr) 2009-05-26 2011-07-15 Sederma Sa Utilisation cosmetique du dipeptide tyr-arg pour lutter contre le relachement cutane.
FR2974297B1 (fr) 2011-04-21 2013-10-04 Sederma Sa Nouvelle utilisation cosmetique ou therapeutique du tripeptide ghk
FR2975904B1 (fr) 2011-06-01 2013-08-23 Sederma Sa Nouvelle utilisation topique, cosmetique ou dermopharmaceutique, d'un melange comprenant un tripeptide du type ghk et un tetrapeptide du type gqpr
FR2998570B1 (fr) 2012-11-26 2016-12-02 Sederma Sa Peptides, compositions les comprenant et utilisations notamment cosmetiques propigmentantes
FR3021319B1 (fr) 2014-05-22 2018-08-31 Sederma Peptides, compositions les comprenant et utilisations notamment cosmetiques
FR3029915B1 (fr) 2014-12-16 2016-12-09 Sederma Sa Tripeptides, compositions les comprenant et utilisations notamment cosmetiques
FR3052453B1 (fr) 2016-06-14 2018-05-18 Sederma Peptide, composition le comprenant et utilisations notamment cosmetiques
FR3079749B1 (fr) 2018-04-05 2022-10-28 Sederma Sa Utilisation d'un peptide pour un traitement de l'epiderme

Also Published As

Publication number Publication date
US20240051994A2 (en) 2024-02-15
US20230137630A1 (en) 2023-05-04
CN115551884A (zh) 2022-12-30
WO2021170754A1 (fr) 2021-09-02
FR3107708A1 (fr) 2021-09-03
EP4110806A1 (fr) 2023-01-04

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