GB1011994A - A process for preparing 5-ribonucleotides - Google Patents

A process for preparing 5-ribonucleotides

Info

Publication number: GB1011994A
Authority: GB; United Kingdom
Prior art keywords: ether; phosphoryl chloride; protected; ribonucleoside; phosphorodichloridate
Prior art date: 1962-01-30
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

GB3906/63A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ajinomoto Co Inc

Original Assignee

Ajinomoto Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1962-01-30

Filing date

1963-01-30

Publication date

1965-12-01

1963-01-30 Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc

1965-12-01 Publication of GB1011994A publication Critical patent/GB1011994A/en

Status Expired legal-status Critical Current

Links

239000002336 ribonucleotide Substances 0.000 title abstract 4
238000004519 manufacturing process Methods 0.000 title abstract 2
XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 12
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 8
NYHBQMYGNKIUIF-UUOKFMHZSA-N Guanosine Chemical compound C1=NC=2C(=O)NC(N)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O NYHBQMYGNKIUIF-UUOKFMHZSA-N 0.000 abstract 4
239000002342 ribonucleoside Substances 0.000 abstract 4
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 3
DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 abstract 2
-1 alkali metal salt Chemical class 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
238000006243 chemical reaction Methods 0.000 abstract 2
230000007062 hydrolysis Effects 0.000 abstract 2
238000006460 hydrolysis reaction Methods 0.000 abstract 2
230000003301 hydrolyzing effect Effects 0.000 abstract 2
PHTQWCKDNZKARW-UHFFFAOYSA-N isoamylol Chemical compound CC(C)CCO PHTQWCKDNZKARW-UHFFFAOYSA-N 0.000 abstract 2
239000002777 nucleoside Substances 0.000 abstract 2
150000003833 nucleoside derivatives Chemical class 0.000 abstract 2
RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 abstract 1
PZHIWRCQKBBTOW-UHFFFAOYSA-N 1-ethoxybutane Chemical compound CCCCOCC PZHIWRCQKBBTOW-UHFFFAOYSA-N 0.000 abstract 1
UNDXPKDBFOOQFC-UHFFFAOYSA-N 4-[2-nitro-4-(trifluoromethyl)phenyl]morpholine Chemical compound [O-][N+](=O)C1=CC(C(F)(F)F)=CC=C1N1CCOCC1 UNDXPKDBFOOQFC-UHFFFAOYSA-N 0.000 abstract 1
ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 abstract 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 abstract 1
229930010555 Inosine Natural products 0.000 abstract 1
229910021578 Iron(III) chloride Inorganic materials 0.000 abstract 1
XOBKSJJDNFUZPF-UHFFFAOYSA-N Methoxyethane Chemical compound CCOC XOBKSJJDNFUZPF-UHFFFAOYSA-N 0.000 abstract 1
229910019142 PO4 Inorganic materials 0.000 abstract 1
DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 abstract 1
DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
150000001241 acetals Chemical class 0.000 abstract 1
UDMBCSSLTHHNCD-KQYNXXCUSA-N adenosine 5'-monophosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O UDMBCSSLTHHNCD-KQYNXXCUSA-N 0.000 abstract 1
150000001298 alcohols Chemical class 0.000 abstract 1
239000003513 alkali Substances 0.000 abstract 1
229910052783 alkali metal Inorganic materials 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
239000003518 caustics Substances 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
150000005676 cyclic carbonates Chemical group 0.000 abstract 1
WVPKAWVFTPWPDB-UHFFFAOYSA-M dichlorophosphinate Chemical compound [O-]P(Cl)(Cl)=O WVPKAWVFTPWPDB-UHFFFAOYSA-M 0.000 abstract 1
WVPKAWVFTPWPDB-UHFFFAOYSA-N dichlorophosphinic acid Chemical group OP(Cl)(Cl)=O WVPKAWVFTPWPDB-UHFFFAOYSA-N 0.000 abstract 1
150000002170 ethers Chemical class 0.000 abstract 1
CQYBANOHCYKAEE-UHFFFAOYSA-N ethynoxyethyne Chemical compound C#COC#C CQYBANOHCYKAEE-UHFFFAOYSA-N 0.000 abstract 1
238000004108 freeze drying Methods 0.000 abstract 1
238000010438 heat treatment Methods 0.000 abstract 1
229960003786 inosine Drugs 0.000 abstract 1
RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 abstract 1
229910001507 metal halide Inorganic materials 0.000 abstract 1
150000005309 metal halides Chemical class 0.000 abstract 1
VNKYTQGIUYNRMY-UHFFFAOYSA-N methoxypropane Chemical compound CCCOC VNKYTQGIUYNRMY-UHFFFAOYSA-N 0.000 abstract 1
239000002773 nucleotide Substances 0.000 abstract 1
125000003729 nucleotide group Chemical group 0.000 abstract 1
239000010452 phosphate Substances 0.000 abstract 1
125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
239000011541 reaction mixture Substances 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
239000011734 sodium Substances 0.000 abstract 1
238000000638 solvent extraction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
- C07H1/02—Phosphorylation
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Saccharide Compounds (AREA)

GB3906/63A 1962-01-30 1963-01-30 A process for preparing 5-ribonucleotides Expired GB1011994A (en)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP256162		1962-01-30
JP1371262		1962-04-11
JP3847362		1962-09-10
JP5096462		1962-11-21

Publications (1)

Publication Number	Publication Date
GB1011994A true GB1011994A (en)	1965-12-01

Family

ID=27453659

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB3906/63A Expired GB1011994A (en)	1962-01-30	1963-01-30	A process for preparing 5-ribonucleotides

Country Status (2)

Country	Link
CH (1)	CH404682A (fr)
GB (1)	GB1011994A (fr)

1963
- 1963-01-30 GB GB3906/63A patent/GB1011994A/en not_active Expired
- 1963-01-30 CH CH113763A patent/CH404682A/fr unknown

Also Published As

Publication number	Publication date
CH404682A (fr)	1965-12-31

Publication	Publication Date	Title
GB855530A (en)	1960-12-07	Improvements in or relating to processes for the removal of water from aqueous liquors
GB1011994A (en)	1965-12-01	A process for preparing 5-ribonucleotides
GB857385A (en)	1960-12-29	Improvements in the preparation or persulphates
GB1513109A (en)	1978-06-07	Method for concentrating aqueous caustic alkali solution
GB662299A (en)	1951-12-05	A process for the purification of rhodium
GB1112643A (en)	1968-05-08	Production of vinyl acetate
US3551489A (en)	1970-12-29	Aqueous process for preparing pseudoureas and acid salts thereof
US3801683A (en)	1974-04-02	Process for preparing trialkyophosphate
GB969419A (en)	1964-09-09	Process for recovering potassium from brines
US2810768A (en)	1957-10-22	Production of glycerine
GB1502928A (en)	1978-03-08	Manufacture of cyanogen
GB957168A (en)	1964-05-06	Improvements in or relating to a process for the electrolytic production of fluorineand apparatus therefor
US4123446A (en)	1978-10-31	Synthesis of metal alkyl carbonates
US4130592A (en)	1978-12-19	Method for the preparation of chloroacetaldehydedimethyl acetal
Hanessian et al.	1967	A new synthesis of chlorodeoxy-sugars
GB1049770A (en)	1966-11-30	Production of omega aminoketocarboxylic acids
GB821388A (en)	1959-10-07	Method of preparing alkali metal hypophosphites
GB1062386A (en)	1967-03-22	Process for preparing pyrazinyl phosphorothioates
GB1042839A (en)	1966-09-14	Production of 5'-nucleotides
GB996082A (en)	1965-06-23	Method of recovering chlorine and hydrogen electrolytically
FR2332970A1 (fr)	1977-06-24	Procede de preparation d'ethers allyliques de phenols et de phenols halogenes
GB1011116A (en)	1965-11-24	Process of producing a 1-halo-1-nitroalkane, and 1-halo-1-nitroalkanes produced by the process
GB470298A (en)	1937-08-12	Process of producing primary amino lower aliphatic alcohols
ES398251A1 (es)	1974-07-16	Procedimiento para preparar bromuro de hidrogeno.
GB1116126A (en)	1968-06-06	Process for the preparation of a mercapto-thiophosphoric acid ester