GB1237798A - Production of isotopically labelled glutamic acid - Google Patents
Production of isotopically labelled glutamic acidInfo
- Publication number
- GB1237798A GB1237798A GB1387769A GB1387769A GB1237798A GB 1237798 A GB1237798 A GB 1237798A GB 1387769 A GB1387769 A GB 1387769A GB 1387769 A GB1387769 A GB 1387769A GB 1237798 A GB1237798 A GB 1237798A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- glutamic acid
- march
- production
- isotopically labelled
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 title 1
- 235000013922 glutamic acid Nutrition 0.000 title 1
- 239000004220 glutamic acid Substances 0.000 title 1
- KPGXRSRHYNQIFN-UHFFFAOYSA-N 2-oxoglutaric acid Chemical compound OC(=O)CCC(=O)C(O)=O KPGXRSRHYNQIFN-UHFFFAOYSA-N 0.000 abstract 2
- 229960005261 aspartic acid Drugs 0.000 abstract 2
- 229960002989 glutamic acid Drugs 0.000 abstract 2
- 230000007935 neutral effect Effects 0.000 abstract 2
- NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonium chloride Substances [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 abstract 1
- 102000004625 Aspartate Aminotransferases Human genes 0.000 abstract 1
- 108010003415 Aspartate Aminotransferases Proteins 0.000 abstract 1
- 108700016171 Aspartate ammonia-lyases Proteins 0.000 abstract 1
- 239000001744 Sodium fumarate Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- HWXBTNAVRSUOJR-UHFFFAOYSA-N alpha-hydroxyglutaric acid Natural products OC(=O)C(O)CCC(O)=O HWXBTNAVRSUOJR-UHFFFAOYSA-N 0.000 abstract 1
- 229940009533 alpha-ketoglutaric acid Drugs 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- MSJMDZAOKORVFC-SEPHDYHBSA-L disodium fumarate Chemical compound [Na+].[Na+].[O-]C(=O)\C=C\C([O-])=O MSJMDZAOKORVFC-SEPHDYHBSA-L 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 230000000155 isotopic effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- KHPXUQMNIQBQEV-UHFFFAOYSA-N oxaloacetic acid Chemical compound OC(=O)CC(=O)C(O)=O KHPXUQMNIQBQEV-UHFFFAOYSA-N 0.000 abstract 1
- 235000007682 pyridoxal 5'-phosphate Nutrition 0.000 abstract 1
- 239000011589 pyridoxal 5'-phosphate Substances 0.000 abstract 1
- 229960001327 pyridoxal phosphate Drugs 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 229940005573 sodium fumarate Drugs 0.000 abstract 1
- 235000019294 sodium fumarate Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA15713 | 1968-03-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1237798A true GB1237798A (en) | 1971-06-30 |
Family
ID=4084114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1387769A Expired GB1237798A (en) | 1968-03-23 | 1969-03-17 | Production of isotopically labelled glutamic acid |
Country Status (7)
| Country | Link |
|---|---|
| BR (1) | BR6907427D0 (fr) |
| CA (1) | CA862079A (fr) |
| CH (1) | CH502969A (fr) |
| DE (1) | DE1914505A1 (fr) |
| FR (1) | FR2004604A1 (fr) |
| GB (1) | GB1237798A (fr) |
| NL (1) | NL6903407A (fr) |
-
1968
- 1968-03-23 CA CA862079A patent/CA862079A/en not_active Expired
-
1969
- 1969-03-05 NL NL6903407A patent/NL6903407A/xx unknown
- 1969-03-17 GB GB1387769A patent/GB1237798A/en not_active Expired
- 1969-03-21 CH CH431869A patent/CH502969A/de not_active IP Right Cessation
- 1969-03-21 BR BR20742769A patent/BR6907427D0/pt unknown
- 1969-03-21 FR FR6908420A patent/FR2004604A1/fr not_active Withdrawn
- 1969-03-21 DE DE19691914505 patent/DE1914505A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR6907427D0 (pt) | 1973-05-10 |
| DE1914505A1 (de) | 1969-10-09 |
| CA862079A (en) | 1971-01-26 |
| NL6903407A (fr) | 1969-09-25 |
| FR2004604A1 (fr) | 1969-11-28 |
| CH502969A (de) | 1971-02-15 |
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