GB2018751A - Tetrahydroalstonine derivatives - Google Patents

Tetrahydroalstonine derivatives

Info

Publication number: GB2018751A
Authority: GB; United Kingdom
Prior art keywords: radical; alkoxy; dialkylamino; alkyl; carbon atoms
Prior art date: 1978-04-14
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Withdrawn

Application number

GB7912932A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Synthelabo SA

Original Assignee

Synthelabo SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-04-14

Filing date

1979-04-12

Publication date

1979-10-24

1978-04-14 Priority claimed from FR7811026A external-priority patent/FR2422664A1/fr

1979-04-12 Application filed by Synthelabo SA filed Critical Synthelabo SA

1979-10-24 Publication of GB2018751A publication Critical patent/GB2018751A/en

Status Withdrawn legal-status Critical Current

Links

GRTOGORTSDXSFK-DLLGKBFGSA-N tetrahydroalstonine Chemical class C1=CC=C2C(CCN3C[C@H]4[C@H](C)OC=C([C@H]4C[C@H]33)C(=O)OC)=C3NC2=C1 GRTOGORTSDXSFK-DLLGKBFGSA-N 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
206010002660 Anoxia Diseases 0.000 abstract 1
208000018152 Cerebral disease Diseases 0.000 abstract 1
206010021143 Hypoxia Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
229910052783 alkali metal Inorganic materials 0.000 abstract 1
150000001340 alkali metals Chemical group 0.000 abstract 1
229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
150000001342 alkaline earth metals Chemical class 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
TUJKJAMUKRIRHC-UHFFFAOYSA-N hydroxyl Chemical compound [OH] TUJKJAMUKRIRHC-UHFFFAOYSA-N 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
-1 piperidino, morpholino, piperazino Chemical group 0.000 abstract 1
230000000506 psychotropic effect Effects 0.000 abstract 1
125000002112 pyrrolidino group Chemical group [*]N1C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

GB7912932A 1978-04-14 1979-04-12 Tetrahydroalstonine derivatives Withdrawn GB2018751A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR7811026A FR2422664A1 (fr)	1978-04-14	1978-04-14	Derives de la tetrahydroalstonine et leur application en therapeutique
FR7906055A FR2450835A2 (fr)	1978-04-14	1979-03-09	Derives de la tetrahydroalstonine et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
GB2018751A true GB2018751A (en)	1979-10-24

Family

ID=26220552

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB7912932A Withdrawn GB2018751A (en)	1978-04-14	1979-04-12	Tetrahydroalstonine derivatives

Country Status (14)

Country	Link
JP (1)	JPS54145700A (fr)
DE (1)	DE2914805A1 (fr)
DK (1)	DK149279A (fr)
ES (1)	ES479540A1 (fr)
FI (1)	FI791194A7 (fr)
FR (1)	FR2450835A2 (fr)
GB (1)	GB2018751A (fr)
GR (1)	GR66991B (fr)
IL (1)	IL57061A0 (fr)
IT (1)	IT1111923B (fr)
LU (1)	LU81145A1 (fr)
NL (1)	NL7902958A (fr)
NO (1)	NO791222L (fr)
PT (1)	PT69487A (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0017525A1 (fr) *	1979-03-14	1980-10-15	Pierre Fabre S.A.	Nouveaux dérivés tétrahydroalstoniques, leur préparation et leur application en tant que médicaments
EP0032889B1 (fr) *	1980-01-09	1984-02-15	OMNICHEM Société anonyme	Nouveaux dérivés du type diméthyl-1,10 oxayohimbane et médicaments les contenant
FR2539416A1 (fr) *	1983-01-14	1984-07-20	Adir	Nouveaux derives oxindoliques, leur procede de preparation et les compositions pharmaceutiques les renfermant

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE501156C2 (sv) *	1993-04-21	1994-11-28	Ellemtel Utvecklings Ab	Referenssignal sammansatt av klocksignal och synkroniseringssignal, anordning och förfarande för synkronisering m.h.a. referenssignal

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1225652B (de) *	1961-08-01	1966-09-29	Boehringer & Soehne Gmbh	Verfahren zur Herstellung von in 1-Stellung substituierten 3, 4, 5, 6-Tetrahydroserpentin-derivaten und von deren Salzen

1979
- 1979-03-09 FR FR7906055A patent/FR2450835A2/fr active Granted
- 1979-04-10 NO NO79791222A patent/NO791222L/no unknown
- 1979-04-10 DK DK149279A patent/DK149279A/da not_active IP Right Cessation
- 1979-04-11 ES ES479540A patent/ES479540A1/es not_active Expired
- 1979-04-11 IT IT21793/79A patent/IT1111923B/it active
- 1979-04-11 DE DE19792914805 patent/DE2914805A1/de not_active Withdrawn
- 1979-04-11 FI FI791194A patent/FI791194A7/fi not_active Application Discontinuation
- 1979-04-11 IL IL57061A patent/IL57061A0/xx unknown
- 1979-04-12 GB GB7912932A patent/GB2018751A/en not_active Withdrawn
- 1979-04-12 LU LU81145A patent/LU81145A1/fr unknown
- 1979-04-12 GR GR58869A patent/GR66991B/el unknown
- 1979-04-12 PT PT69487A patent/PT69487A/fr unknown
- 1979-04-12 NL NL7902958A patent/NL7902958A/xx not_active Application Discontinuation
- 1979-04-13 JP JP4595879A patent/JPS54145700A/ja active Pending

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0017525A1 (fr) *	1979-03-14	1980-10-15	Pierre Fabre S.A.	Nouveaux dérivés tétrahydroalstoniques, leur préparation et leur application en tant que médicaments
EP0032889B1 (fr) *	1980-01-09	1984-02-15	OMNICHEM Société anonyme	Nouveaux dérivés du type diméthyl-1,10 oxayohimbane et médicaments les contenant
FR2539416A1 (fr) *	1983-01-14	1984-07-20	Adir	Nouveaux derives oxindoliques, leur procede de preparation et les compositions pharmaceutiques les renfermant

Also Published As

Publication number	Publication date
NO791222L (no)	1979-10-16
FR2450835B2 (fr)	1982-11-19
LU81145A1 (fr)	1980-12-16
ES479540A1 (es)	1979-07-16
FR2450835A2 (fr)	1980-10-03
NL7902958A (nl)	1979-10-16
IT1111923B (it)	1986-01-13
GR66991B (fr)	1981-05-18
JPS54145700A (en)	1979-11-14
DE2914805A1 (de)	1979-10-18
DK149279A (da)	1979-10-15
FI791194A7 (fi)	1979-10-15
IT7921793A0 (it)	1979-04-11
PT69487A (fr)	1979-05-01
IL57061A0 (en)	1979-07-25

Legal Events

Date	Code	Title	Description
1983-02-09	WAP	Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)

Publication	Publication Date	Title
ES8306141A1 (es)	1983-05-01	Un procedimiento para la produccion de un derivado de carbostirilo
GB2263110B (en)	1995-08-09	Piperazine derivatives
PH20468A (en)	1987-01-14	Novel pharmaceutically active di-esters of 3,5-dicarboxy-4-substituted-pyridines and pyrans
WO1988000042A1 (en)	1988-01-14	New 5-alkoxy-2,4-diamino-alkyl benzols, and hair tinting means using them
HUT44041A (en)	1988-01-28	Process for producing new diamino-androstane derivatives
ES8104321A1 (es)	1981-04-01	Procedimiento para separar un derivado de alquil-cetohexopi-ranosida
ES8503667A1 (es)	1985-03-16	Un procedimiento para la preparacion de nuevos derivados de 2-oxo-imidazolina.
GB2191196B (en)	1990-03-28	Imidazo pyrimidines
ES8401014A1 (es)	1983-12-01	Un procedimiento para la preparacion de nuevos derivados de propanolamina.
HUT38927A (en)	1986-07-28	Process for producing 5-alkyl-1-phenyl-2-/piperazino-alkyl/-pyrazolin-3-one derivatives
ES479540A1 (es)	1979-07-16	Procedimiento para preparar derivados de la tetrahidroalsto-nina.
DE3372095D1 (en)	1987-07-23	Novel phenylpiperazine derivatives and process for producing the same
IE800968L (en)	1980-11-11	Pyrazinobenzodiazepines
SE8304071L (sv)	1984-06-03	Nya piperazinderivat
HU9502179D0 (en)	1995-09-28	Piperazine derivatives for producing alkyl-trazodon derivatives and process for producing them
HUT50464A (en)	1990-02-28	Process for producing phenothiazin derivatives
ES8504159A1 (es)	1985-04-16	Un procedimiento para la preparacion de nuevos derivados de 1,2,5,-tidiazol.
AU559732B2 (en)	1987-03-19	Di-and-tetrahydroguinolylacetic acid esters
IE780262L (en)	1978-08-08	Carbocyclic fused thiophen-2-oxaminic acid derivatives
ES8607951A1 (es)	1986-06-01	Procedimiento para la obtencion de un derivado de sulfonilguanidina
ATE77744T1 (de)	1992-07-15	Verwendung von pyrrothinderivaten.
ES449446A1 (es)	1977-12-01	Un procedimiento para la produccion de acidos 1-oxo-1h-6-pi-peridinogicamente activos y esteres de los mismos.
GR72839B (fr)	1983-12-07
GB2071093B (en)	1984-01-18	Benzothiopyrano(2,3-c)pyridines
ES8206521A1 (es)	1982-01-16	Un procedimiento de preparacion de derivados del acido oxa- yohimbano-carboxilico

GB2018751A - Tetrahydroalstonine derivatives - Google Patents

Info

Links

Classifications

Landscapes

Applications Claiming Priority (2)

Publications (1)

Family

ID=26220552

Family Applications (1)

Country Status (14)

Cited By (3)

Families Citing this family (1)

Family Cites Families (1)

Cited By (3)

Also Published As

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Legal Events