GB2556830A - Resonance mass separator - Google Patents

Resonance mass separator

Info

Publication number
GB2556830A
GB2556830A GB1804549.2A GB201804549A GB2556830A GB 2556830 A GB2556830 A GB 2556830A GB 201804549 A GB201804549 A GB 201804549A GB 2556830 A GB2556830 A GB 2556830A
Authority
GB
United Kingdom
Prior art keywords
ion
rms
resonant
isochronous
electric field
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB1804549.2A
Other versions
GB201804549D0 (en
Inventor
Vedenin Alexander
Verenchikov Anatoly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Q-Tek d o o
Q Tek d o o
Original Assignee
Q-Tek d o o
Q Tek d o o
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Q-Tek d o o, Q Tek d o o filed Critical Q-Tek d o o
Publication of GB201804549D0 publication Critical patent/GB201804549D0/en
Publication of GB2556830A publication Critical patent/GB2556830A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/421—Mass filters, i.e. deviating unwanted ions without trapping

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Electron Tubes For Measurement (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Disclosed is a resonant mass separator (RMS) and method of resonant mass separation are based on passing of continuous or gently modulated ion beams through electric field of an isochronous open trap so that ions isochronously oscillate (reflect or turn) in one plane and slowly progress in the orthogonal direction. Spatially localized excitation electric field is energized periodically, preferably at much higher frequencies compared to ion oscillations. Spatially local AC excitation within isochronous open traps is found to produce an effect of resonant stabilization and effective transmission of selected narrow mass bands, while deflecting or defocusing other ionic components. The open trap may employ a dipolar RF filter, or electrostatic sector multi-turn analyzer, or multi-reflecting analyzerbased on ion mirrors. Preferably, continuous ion beams are pulsed modulated to reach near unity transmission at high (for separators) resolving power of 10,000. Tandem MS-MS is the most preferred application of RMS. In one method, multiple parent ion windows are passed through the RMS for tandem analysis, thus reaching higher throughput of MS and MS-MS analyses.
GB1804549.2A 2015-09-10 2016-08-31 Resonance mass separator Withdrawn GB2556830A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1516057.5A GB201516057D0 (en) 2015-09-10 2015-09-10 Resonance mass separator
PCT/IB2016/055201 WO2017042665A1 (en) 2015-09-10 2016-08-31 Resonance mass separator

Publications (2)

Publication Number Publication Date
GB201804549D0 GB201804549D0 (en) 2018-05-02
GB2556830A true GB2556830A (en) 2018-06-06

Family

ID=54362980

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB1516057.5A Ceased GB201516057D0 (en) 2015-09-10 2015-09-10 Resonance mass separator
GB1804549.2A Withdrawn GB2556830A (en) 2015-09-10 2016-08-31 Resonance mass separator

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB1516057.5A Ceased GB201516057D0 (en) 2015-09-10 2015-09-10 Resonance mass separator

Country Status (2)

Country Link
GB (2) GB201516057D0 (en)
WO (1) WO2017042665A1 (en)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10950425B2 (en) 2016-08-16 2021-03-16 Micromass Uk Limited Mass analyser having extended flight path
US11049712B2 (en) 2017-08-06 2021-06-29 Micromass Uk Limited Fields for multi-reflecting TOF MS
US11081332B2 (en) 2017-08-06 2021-08-03 Micromass Uk Limited Ion guide within pulsed converters
US11205568B2 (en) 2017-08-06 2021-12-21 Micromass Uk Limited Ion injection into multi-pass mass spectrometers
US11211238B2 (en) 2017-08-06 2021-12-28 Micromass Uk Limited Multi-pass mass spectrometer
US11239067B2 (en) 2017-08-06 2022-02-01 Micromass Uk Limited Ion mirror for multi-reflecting mass spectrometers
US11295944B2 (en) 2017-08-06 2022-04-05 Micromass Uk Limited Printed circuit ion mirror with compensation
US11309175B2 (en) 2017-05-05 2022-04-19 Micromass Uk Limited Multi-reflecting time-of-flight mass spectrometers
US11328920B2 (en) 2017-05-26 2022-05-10 Micromass Uk Limited Time of flight mass analyser with spatial focussing
US11342175B2 (en) 2018-05-10 2022-05-24 Micromass Uk Limited Multi-reflecting time of flight mass analyser
US11367608B2 (en) 2018-04-20 2022-06-21 Micromass Uk Limited Gridless ion mirrors with smooth fields
US11587779B2 (en) 2018-06-28 2023-02-21 Micromass Uk Limited Multi-pass mass spectrometer with high duty cycle
US11621156B2 (en) 2018-05-10 2023-04-04 Micromass Uk Limited Multi-reflecting time of flight mass analyser
US11817303B2 (en) 2017-08-06 2023-11-14 Micromass Uk Limited Accelerator for multi-pass mass spectrometers
US11848185B2 (en) 2019-02-01 2023-12-19 Micromass Uk Limited Electrode assembly for mass spectrometer
US11881387B2 (en) 2018-05-24 2024-01-23 Micromass Uk Limited TOF MS detection system with improved dynamic range
US12205813B2 (en) 2019-03-20 2025-01-21 Micromass Uk Limited Multiplexed time of flight mass spectrometer

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201907171D0 (en) * 2019-05-21 2019-07-03 Thermo Fisher Scient Bremen Gmbh Switchable ion guide
GB2638099B (en) 2021-04-07 2026-01-21 HGSG Ltd Mass spectrometer and method
GB2630649A (en) 2023-06-02 2024-12-04 HGSG Ltd Mass spectrometer and method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1933366A1 (en) * 2006-12-14 2008-06-18 Tofwerk AG Apparatus for mass analysis of ions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1933366A1 (en) * 2006-12-14 2008-06-18 Tofwerk AG Apparatus for mass analysis of ions

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10950425B2 (en) 2016-08-16 2021-03-16 Micromass Uk Limited Mass analyser having extended flight path
US11309175B2 (en) 2017-05-05 2022-04-19 Micromass Uk Limited Multi-reflecting time-of-flight mass spectrometers
US11328920B2 (en) 2017-05-26 2022-05-10 Micromass Uk Limited Time of flight mass analyser with spatial focussing
US11211238B2 (en) 2017-08-06 2021-12-28 Micromass Uk Limited Multi-pass mass spectrometer
US11756782B2 (en) 2017-08-06 2023-09-12 Micromass Uk Limited Ion mirror for multi-reflecting mass spectrometers
US11239067B2 (en) 2017-08-06 2022-02-01 Micromass Uk Limited Ion mirror for multi-reflecting mass spectrometers
US11295944B2 (en) 2017-08-06 2022-04-05 Micromass Uk Limited Printed circuit ion mirror with compensation
US11081332B2 (en) 2017-08-06 2021-08-03 Micromass Uk Limited Ion guide within pulsed converters
US11049712B2 (en) 2017-08-06 2021-06-29 Micromass Uk Limited Fields for multi-reflecting TOF MS
US11817303B2 (en) 2017-08-06 2023-11-14 Micromass Uk Limited Accelerator for multi-pass mass spectrometers
US11205568B2 (en) 2017-08-06 2021-12-21 Micromass Uk Limited Ion injection into multi-pass mass spectrometers
US11367608B2 (en) 2018-04-20 2022-06-21 Micromass Uk Limited Gridless ion mirrors with smooth fields
US11621156B2 (en) 2018-05-10 2023-04-04 Micromass Uk Limited Multi-reflecting time of flight mass analyser
US11342175B2 (en) 2018-05-10 2022-05-24 Micromass Uk Limited Multi-reflecting time of flight mass analyser
US11881387B2 (en) 2018-05-24 2024-01-23 Micromass Uk Limited TOF MS detection system with improved dynamic range
US11587779B2 (en) 2018-06-28 2023-02-21 Micromass Uk Limited Multi-pass mass spectrometer with high duty cycle
US11848185B2 (en) 2019-02-01 2023-12-19 Micromass Uk Limited Electrode assembly for mass spectrometer
US12205813B2 (en) 2019-03-20 2025-01-21 Micromass Uk Limited Multiplexed time of flight mass spectrometer

Also Published As

Publication number Publication date
GB201516057D0 (en) 2015-10-28
GB201804549D0 (en) 2018-05-02
WO2017042665A1 (en) 2017-03-16

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Legal Events

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WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)