GR1000373B - Μεθοδος παρασκευης νεων παραγωγων 1,4-βενζοξαζινης και 1,4-βεν ζοθειαζινης - Google Patents

Μεθοδος παρασκευης νεων παραγωγων 1,4-βενζοξαζινης και 1,4-βεν ζοθειαζινης

Info

Publication number
GR1000373B
GR1000373B GR890100065A GR890100065A GR1000373B GR 1000373 B GR1000373 B GR 1000373B GR 890100065 A GR890100065 A GR 890100065A GR 890100065 A GR890100065 A GR 890100065A GR 1000373 B GR1000373 B GR 1000373B
Authority
GR
Greece
Prior art keywords
benzoaxazinene
benzothiazine
preparing
preparation
following formula
Prior art date
Application number
GR890100065A
Other languages
English (en)
Inventor
Alberto Bonsignori
Antonietta Maria Cervini
Roberto Commisso
Piero Melloni
Mario Varasi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of GR1000373B publication Critical patent/GR1000373B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Η παρούσα εφεύρεσις αφορά μίαν μέθοδον δια την παρασκευήν νέων ενώσεων αι οποίαι έχουν τον ακόλουθο τύπον (Ι) ω
GR890100065A 1988-02-15 1989-02-03 Μεθοδος παρασκευης νεων παραγωγων 1,4-βενζοξαζινης και 1,4-βεν ζοθειαζινης GR1000373B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888803419A GB8803419D0 (en) 1988-02-15 1988-02-15 1 4-benzoxazine & 1 4-benzothiazine derivatives & process for their preparation

Publications (1)

Publication Number Publication Date
GR1000373B true GR1000373B (el) 1992-06-30

Family

ID=10631705

Family Applications (1)

Application Number Title Priority Date Filing Date
GR890100065A GR1000373B (el) 1988-02-15 1989-02-03 Μεθοδος παρασκευης νεων παραγωγων 1,4-βενζοξαζινης και 1,4-βεν ζοθειαζινης

Country Status (19)

Country Link
US (1) US5084454A (el)
EP (1) EP0359790B1 (el)
JP (1) JPH02503200A (el)
KR (1) KR900700468A (el)
CA (1) CA1327575C (el)
DE (1) DE68910451T2 (el)
DK (1) DK506289A (el)
ES (1) ES2012648A6 (el)
FI (1) FI894798A7 (el)
GB (1) GB8803419D0 (el)
GR (1) GR1000373B (el)
HU (1) HU204517B (el)
IE (1) IE890464L (el)
IL (1) IL89035A (el)
NZ (1) NZ227739A (el)
PT (1) PT89715B (el)
RU (1) RU1826968C (el)
WO (1) WO1989007596A1 (el)
ZA (1) ZA891107B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240927A (en) * 1992-05-19 1993-08-31 Hoechst-Roussel Pharmaceuticals Incorporated Benzo[β]thiophen-3-yl piperazines as antipsychotic agents
FR2702477B1 (fr) * 1993-03-08 1995-04-28 Synthelabo Dérivés de benzoxazine, leur préparation et leur application en thérapeutique.
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
US5691323A (en) * 1995-05-12 1997-11-25 Merck & Co., Inc. Muscarine antagonists
US6162803A (en) * 1998-04-08 2000-12-19 American Home Products Corp. Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression
JP3201998B2 (ja) * 1998-12-16 2001-08-27 サムソン ジェネラル ケミカルズ カンパニー リミテッド （ｓ）−ベンゾオキサジン誘導体の製造方法及び（ｒ）−ベンゾオキサジン誘導体のラセミ化方法
WO2000040581A1 (en) * 1999-01-07 2000-07-13 American Home Products Corporation 3,4-dihydro-2h-benzo[1,4]oxazine derivatives
TW546299B (en) * 1999-01-07 2003-08-11 Wyeth Corp 3,4-dihydro-2H-benzo[1,4]oxazinyl-methyl-[3-(1H-indol-3-yl)-alkyl]-amines
US6313114B1 (en) 1999-01-07 2001-11-06 American Home Products Corp 3,4-Dihydro-2H-benzo[1,4]oxazinyl-methyl)-[3-(1H-indol-3yl)-alkyl]- amines
US6221863B1 (en) 1999-01-07 2001-04-24 American Home Products Corp. 3,4-dihydro-2H-benzo[1,4]oxazine derivatives
US6451830B1 (en) 1999-09-23 2002-09-17 G.D. Searle & Co. Use of substituted N,N-disubstituted non-fused heterocyclo amino compounds for inhibiting cholesteryl ester transfer protein activity
US6544974B2 (en) 1999-09-23 2003-04-08 G.D. Searle & Co. (R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesteryl ester transfer protein activity
AU2004299201B2 (en) * 2003-12-09 2009-12-03 F. Hoffmann-La Roche Ag Benzoxazine derivatives and uses thereof
CN101836993B (zh) 2010-05-20 2011-06-22 山东大学 2，3-二氢-3-羟甲基-6-氨基-[1，4]-苯并噁嗪在制备诱导胚胎干细胞向血管内皮细胞分化药物中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2080791A (en) * 1980-06-19 1982-02-10 Erba Farmitalia 1,4-Benzoxazines
EP0204148A2 (en) * 1985-05-07 1986-12-10 Hoechst Uk Limited [1,4]Benzodioxin and [1,4]benzoxazine derivatives
EP0233728A1 (en) * 1986-02-11 1987-08-26 Takeda Chemical Industries, Ltd. 1,4-Benzoxazine derivatives their production and use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3058980A (en) * 1962-10-16 Substitution products of benzo-

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2080791A (en) * 1980-06-19 1982-02-10 Erba Farmitalia 1,4-Benzoxazines
EP0204148A2 (en) * 1985-05-07 1986-12-10 Hoechst Uk Limited [1,4]Benzodioxin and [1,4]benzoxazine derivatives
EP0233728A1 (en) * 1986-02-11 1987-08-26 Takeda Chemical Industries, Ltd. 1,4-Benzoxazine derivatives their production and use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CLAIMS SEARCHED: ALL *

Also Published As

Publication number Publication date
EP0359790B1 (en) 1993-11-03
PT89715A (pt) 1989-10-04
NZ227739A (en) 1990-08-28
HUT56354A (en) 1991-08-28
HU204517B (en) 1992-01-28
DK506289D0 (da) 1989-10-12
WO1989007596A1 (en) 1989-08-24
FI894798A0 (fi) 1989-10-10
EP0359790A1 (en) 1990-03-28
ZA891107B (en) 1989-10-25
DE68910451D1 (de) 1993-12-09
JPH02503200A (ja) 1990-10-04
DE68910451T2 (de) 1994-03-03
IE890464L (en) 1989-08-15
KR900700468A (ko) 1990-08-13
RU1826968C (ru) 1993-07-07
GB8803419D0 (en) 1988-03-16
ES2012648A6 (es) 1990-04-01
HU891441D0 (en) 1990-01-28
IL89035A (en) 1994-05-30
US5084454A (en) 1992-01-28
CA1327575C (en) 1994-03-08
IL89035A0 (en) 1989-08-15
FI894798A7 (fi) 1989-10-10
PT89715B (pt) 1994-03-31
DK506289A (da) 1989-10-12

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