GR1000430B - Αντισωματα δι' αγγειογενινην και μεθοδος παρασκευης ανοσοθεραπευτικων παραγοντων. - Google Patents

Αντισωματα δι' αγγειογενινην και μεθοδος παρασκευης ανοσοθεραπευτικων παραγοντων.

Info

Publication number
GR1000430B
GR1000430B GR890100489A GR890100489A GR1000430B GR 1000430 B GR1000430 B GR 1000430B GR 890100489 A GR890100489 A GR 890100489A GR 890100489 A GR890100489 A GR 890100489A GR 1000430 B GR1000430 B GR 1000430B
Authority
GR
Greece
Prior art keywords
angiogenin
asntibodies
preparating
immunotherapeutic agents
angiogenesis
Prior art date
Application number
GR890100489A
Other languages
English (en)
Inventor
Edward M Alderman
James W Fett
Bert L Vallee
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of GR1000430B publication Critical patent/GR1000430B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/828—Cancer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Η εφεύρεσις αυτή αφορά την παρασκευήν αντισωμάτων δι'αγγειογενίνην ή κλάσματα αυτής και μεθόδους προς παρεμπόδισιν της αγγειογενέσεως εις θηλαστικά δια χορηγήσεως εις θηλαστικά τοιούτων αντισωμάτων ή κλασμάτων Fab ή F(ab')2 αυτών ούτως ώστε να παρεμποδισθή η αγγειογενετική δραστικότης. Επί πλέον η εφεύρεσις αυτή αφορά φαρμακευτικάς συνθέσεις αι οποίαι περιέχουν θεραπευτικώς αποτελεσματικάς ποσότητας αντισωμάτων, τα οποία είναι ανοσοποιητικώς ικανά προς αντίδρασιν με αγγειογενίνην και τα οποία είναι δυνατόν να χορηγηθούν δια να παρεμποδίσουν την αγγειογένεσιν. ω
GR890100489A 1987-08-06 1989-08-03 Αντισωματα δι' αγγειογενινην και μεθοδος παρασκευης ανοσοθεραπευτικων παραγοντων. GR1000430B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/083,231 US4853219A (en) 1987-08-06 1987-08-06 Antibodies to angiogenin: immunotherapeutic agents
PCT/US1988/002590 WO1989000862A1 (en) 1987-08-06 1988-08-05 Antibodies to angiogenin: immunotherapeutic agents

Publications (1)

Publication Number Publication Date
GR1000430B true GR1000430B (el) 1992-07-30

Family

ID=22177021

Family Applications (1)

Application Number Title Priority Date Filing Date
GR890100489A GR1000430B (el) 1987-08-06 1989-08-03 Αντισωματα δι' αγγειογενινην και μεθοδος παρασκευης ανοσοθεραπευτικων παραγοντων.

Country Status (13)

Country Link
US (1) US4853219A (el)
EP (1) EP0436526B1 (el)
JP (1) JPH02504512A (el)
KR (1) KR920005691B1 (el)
AT (1) ATE133075T1 (el)
AU (1) AU618024B2 (el)
CA (1) CA1341425C (el)
DE (1) DE3854926T2 (el)
DK (1) DK29490A (el)
ES (1) ES2015349A6 (el)
GR (1) GR1000430B (el)
PT (1) PT88314A (el)
WO (1) WO1989000862A1 (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5520914A (en) * 1987-08-06 1996-05-28 President And Fellows Of Harvard College Antibodies to angiogenin: immunotherapeutic agents
FR2623509B1 (fr) * 1987-11-19 1990-04-20 Centre Nat Rech Scient Proteine de 17 kd a action angiogenique, son procede d'isolement a partir de lait de mammiferes, compositions therapeutiques la contenant, procede de detection et/ou de dosage et reactifs immunologiques de detection et de dosage des angiogenines de mammiferes, de leurs homologues et de leurs fragments
US6929907B2 (en) * 1999-12-31 2005-08-16 North Carolina State University Methods and compositions for determining the purity of chemically synthesized nucleic acids
RU2197263C1 (ru) * 2001-05-16 2003-01-27 Московский областной научно-исследовательский клинический институт Способ лечения ран и язвенных дефектов
WO2002100899A2 (de) 2001-06-13 2002-12-19 Osteopep-Pharma Gmbh Arzneimittel zur behandlung von tumoren und deren metastasen unter verwendung eines bindemoleküls gegen das bone-sialoprotein
CA2814598A1 (en) * 2005-09-12 2007-03-22 The Regents Of The University Of Michigan Recurrent gene fusions in prostate cancer
AU2007246921A1 (en) * 2006-04-10 2007-11-15 Fusion Antibodies Limited Therapy targeting Cathepsin S

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0234545A2 (en) * 1986-02-24 1987-09-02 Clemens Prof. Dr. Sorg Purified human angiogenic factor, method for its preparation and pharmaceutical preparations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229532A (en) * 1978-12-29 1980-10-21 Monsanto Company Production of tumor angiogenesis factor by cell culture
US4229531A (en) * 1978-12-29 1980-10-21 Monsanto Company Production of tumor angiogenesis factor by cell culture
US4273871A (en) * 1980-03-03 1981-06-16 Monsanto Company Production of angiogenic factor by cell culture
DE3110560A1 (de) * 1981-03-18 1982-10-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen "angiotropine der leukozyten und des entzuendungsgewebes: eine neue klasse natuerlicher chemotropischer mitogene fuer das richtungswachstum von blutgefaessen und zur neovaskularisierung von geweben"
GB2131294B (en) * 1982-11-30 1987-06-10 Univ Manchester Low molecular weight angiogenic factor
US4529590A (en) * 1982-12-27 1985-07-16 Leveen Robert F Production of angiogenetic factor
US4503038A (en) * 1983-02-25 1985-03-05 The Regents Of The University Of California Extracellular nonmitogenic angiogenesis factor and method of isolation thereof from wound fluid
US4699788A (en) * 1984-08-20 1987-10-13 Trustees Of Boston University Angiogenic factor methods of extraction and method for producing angiogenesis
US4727137A (en) * 1985-04-17 1988-02-23 President And Fellows Of Harvard College Purified protein having angiogenic activity and methods of preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0234545A2 (en) * 1986-02-24 1987-09-02 Clemens Prof. Dr. Sorg Purified human angiogenic factor, method for its preparation and pharmaceutical preparations

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CLAIMS SEARCHED: 1-9; CLAIMS NOT SEARCHED: 10-15 *

Also Published As

Publication number Publication date
EP0436526A1 (en) 1991-07-17
US4853219A (en) 1989-08-01
AU2316688A (en) 1989-03-01
KR920005691B1 (ko) 1992-07-13
CA1341425C (en) 2003-03-18
WO1989000862A1 (en) 1989-02-09
DK29490A (da) 1990-03-30
AU618024B2 (en) 1991-12-12
PT88314A (pt) 1989-06-30
EP0436526A4 (en) 1990-08-20
ATE133075T1 (de) 1996-02-15
JPH02504512A (ja) 1990-12-20
DE3854926D1 (de) 1996-02-29
ES2015349A6 (es) 1990-08-16
KR890701130A (ko) 1989-12-19
EP0436526B1 (en) 1996-01-17
DE3854926T2 (de) 1996-05-30
DK29490D0 (da) 1990-02-05

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