GR1000457B - Novel compounds - Google Patents

Novel compounds

Info

Publication number
GR1000457B
GR1000457B GR890100115A GR890100115A GR1000457B GR 1000457 B GR1000457 B GR 1000457B GR 890100115 A GR890100115 A GR 890100115A GR 890100115 A GR890100115 A GR 890100115A GR 1000457 B GR1000457 B GR 1000457B
Authority
GR
Greece
Prior art keywords
endotoxins
active
mutant
endotoxin
novel compounds
Prior art date
Application number
GR890100115A
Other languages
Greek (el)
Inventor
Lou Cindy Jellis
Robert James Rusche
Parker Daniel Witt
Original Assignee
Sandoz Ag
Sandoz Sa
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag, Sandoz Sa, Sandoz Ltd filed Critical Sandoz Ag
Publication of GR1000457B publication Critical patent/GR1000457B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Μεταλλακτικές ενδοτοξίνες πρωτεϊνες BACILLUS THURINGIENSIS, που εμφανίζουν την χαρακτηριστική εντομοκτόνο ενεργότητα που εμφανίζεται από τις άγριου τύπου δ-ενδοτοξίνες. Σε κάθε ατομικό σημείο μετάλλαξης υποδείχνεται ότι τα κωδικόνια που κωδικοποιούν για οποιοδήποτε άλλο φυσικό αμινοξύ μπορούν να χρησιμοποιήθουν για αντικατάσταση προς παραγωγή ενεργού ενδοτοξίνης πρωτεϊνης. Επίσης περιγράφονται αλληλουχίες DNA που κωδικοποιούν παρόμοιες ενδοτοξίνες και ανασυνδιαστικές τεχνικές για την παραγωγή της εντομοκτόνα ενεργού μεταλλακτικής ενδοτοξίνης. ωMutant endotoxins BACILLUS THURINGIENSIS proteins, which exhibit the characteristic insecticidal activity exhibited by wild-type δ-endotoxins. It is indicated at each individual mutation site that the codons encoding any other natural amino acid can be used as a substitute to produce an active endotoxin protein. Also described are DNA sequences encoding similar endotoxins and recombinant techniques for producing the active mutant endotoxin insecticide. ω

GR890100115A 1988-02-25 1989-02-23 Novel compounds GR1000457B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16023388A 1988-02-25 1988-02-25

Publications (1)

Publication Number Publication Date
GR1000457B true GR1000457B (en) 1992-07-30

Family

ID=22576065

Family Applications (1)

Application Number Title Priority Date Filing Date
GR890100115A GR1000457B (en) 1988-02-25 1989-02-23 Novel compounds

Country Status (23)

Country Link
JP (1) JPH025872A (en)
CN (1) CN1037538A (en)
AT (1) AT396940B (en)
AU (1) AU616945B2 (en)
BE (1) BE1001877A4 (en)
BR (1) BR8900881A (en)
DE (1) DE3905865A1 (en)
DK (1) DK84589A (en)
ES (1) ES2012283A6 (en)
FR (1) FR2627778B1 (en)
GB (1) GB2216127B (en)
GR (1) GR1000457B (en)
HU (1) HU209148B (en)
IE (1) IE62118B1 (en)
IL (1) IL89391A (en)
IT (1) IT1230483B (en)
MY (1) MY104405A (en)
NL (1) NL8900481A (en)
NZ (1) NZ228108A (en)
PL (1) PL161726B1 (en)
PT (1) PT89812B (en)
TR (1) TR26073A (en)
ZA (1) ZA891463B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8910624D0 (en) * 1989-05-09 1989-06-21 Ici Plc Bacterial strains
CA2032405A1 (en) * 1989-12-18 1991-06-19 Cindy L. Jellis Organic compounds
GB9408466D0 (en) * 1994-04-27 1994-06-22 Univ Nottingham Cloning and functional expression of neurotoxins
EP0861021B1 (en) * 1995-10-13 2009-09-23 Dow Agrosciences LLC Modified bacillus thuringiensis gene for lepidopteran control in plants
US6474576B1 (en) 1999-03-10 2002-11-05 Sumitomo Special Metals Co., Ltd. Milling apparatus and milling method
JP4855772B2 (en) * 2005-12-21 2012-01-18 ノリタケ伊勢電子株式会社 Fluorescent display device
JP4753987B2 (en) 2008-11-10 2011-08-24 双葉電子工業株式会社 Fluorescent display tube and driving method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2540484B2 (en) * 1984-12-12 1996-10-02 サントリー株式会社 Gene coding for insecticidal protein
EP0206613B1 (en) * 1985-06-14 1992-08-19 Repligen Corporation Activated bacillus thuringienses delta-endotoxin produced by an engineered hybrid gene
CA1341092C (en) * 1985-12-12 2000-09-05 David L. Edwards Process for altering the host range of bacillus thuringiensis toxins, and novel toxins produced thereby
DE3855827T2 (en) * 1987-04-16 1997-11-27 Ecogen Inc BACILLUS THURINGIENSIS P-2 TOXING, PROTEIN AND RELATED INSECTICIDE COMPOSITIONS

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CLAIMS SEARCHED: ALL *
EUR. J. BIOCHEM., vol. 161, December 1986, pages 273-280, FEBS; H. H\FTE et al.: "Structural and functional analysis of a cloned delta endotoxin of Bacillus thuringiensis berliner 1715" *
GENE, vol. 48, 1986, pages 109-118, Elsevier Science Publishers B.V. (Biomedical Division); M. GEISER et al.: "The hypervariable region in the genes coding for entomopathogenic crystal proteins of Bacillus thuringiensis: nucleotide sequence of the Kurhdl gene of subsp. Kurstaki HD1" *
NATURE, vol. 328, no. 6125, 2nd - 8th July 1987, pages 33-37, London, GB; M. VAECK et al.: "Transgenic plants protected from insect attack" *

Also Published As

Publication number Publication date
IE62118B1 (en) 1994-12-14
NZ228108A (en) 1992-04-28
JPH025872A (en) 1990-01-10
ZA891463B (en) 1990-10-31
IT1230483B (en) 1991-10-24
GB8904016D0 (en) 1989-04-05
GB2216127A (en) 1989-10-04
IE890589L (en) 1989-08-25
TR26073A (en) 1993-12-16
IL89391A (en) 1995-01-24
HU209148B (en) 1994-03-28
BE1001877A4 (en) 1990-04-03
FR2627778B1 (en) 1990-09-21
GB2216127B (en) 1991-11-06
NL8900481A (en) 1989-09-18
PT89812B (en) 1994-04-29
PL277925A1 (en) 1990-02-05
ATA41389A (en) 1993-05-15
PL161726B1 (en) 1993-07-30
IL89391A0 (en) 1989-09-10
DK84589A (en) 1989-08-26
IT8947678A0 (en) 1989-02-22
MY104405A (en) 1994-03-31
AU616945B2 (en) 1991-11-14
AT396940B (en) 1993-12-27
PT89812A (en) 1989-10-04
CN1037538A (en) 1989-11-29
BR8900881A (en) 1989-10-17
HUT50507A (en) 1990-02-28
DE3905865A1 (en) 1989-09-07
DK84589D0 (en) 1989-02-23
AU3029789A (en) 1989-10-12
ES2012283A6 (en) 1990-03-01
FR2627778A1 (en) 1989-09-01

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