GR1001459B - Σύμπλεγμα συζυγών φαρμάκων με αντισώματα. - Google Patents

Σύμπλεγμα συζυγών φαρμάκων με αντισώματα.

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Publication number
GR1001459B
GR1001459B GR920100429A GR920100429A GR1001459B GR 1001459 B GR1001459 B GR 1001459B GR 920100429 A GR920100429 A GR 920100429A GR 920100429 A GR920100429 A GR 920100429A GR 1001459 B GR1001459 B GR 1001459B
Authority
GR
Greece
Prior art keywords
insoindoline
derivatives
production
optically active
conjugates
Prior art date
Application number
GR920100429A
Other languages
English (en)
Inventor
Gary Allen Koppel
E Robin Offord
Keith Rose
William Leonard Scott
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR1001459B publication Critical patent/GR1001459B/el

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Abstract

Δίδονται συζυγιακές ενώσεις φαρμάκων κατευθυνόμενες προς ένα στόχο, οι οποίες καθιστούν δυνατόν να κατευθυνθεί εις ένα κύτταρον ένας μεγάλος αριθμός μορίων φαρμάκου δι' ενός μόνον μορίου αντισώματος. Η εφεύρεσις δίδει επίσης ενδιάμεσες ενώσεις δια την σύνθεσιν τέτοιων συζυγιακών ενώσεων και κυτταροτοξικών φαρμάκων, οι οποίες έχουν τροποποιηθεί συμφώνως προς την αρχήν ομάδος της εφευρέσεως.ω
GR920100429A 1992-10-08 1992-10-08 Σύμπλεγμα συζυγών φαρμάκων με αντισώματα. GR1001459B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR92100429 1992-10-08

Publications (1)

Publication Number Publication Date
GR1001459B true GR1001459B (el) 1993-12-30

Family

ID=10941198

Family Applications (1)

Application Number Title Priority Date Filing Date
GR920100429A GR1001459B (el) 1992-10-08 1992-10-08 Σύμπλεγμα συζυγών φαρμάκων με αντισώματα.

Country Status (1)

Country Link
GR (1) GR1001459B (el)

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088695A2 (en) * 1982-03-09 1983-09-14 Cytogen Corporation Antibody conjugates
EP0328147A2 (en) * 1988-02-11 1989-08-16 Bristol-Myers Squibb Company Anthracycline immunoconjugates having a novel linker and methods for their production
EP0354728A2 (en) * 1988-08-08 1990-02-14 Eli Lilly And Company Cytotoxic drug conjugates
EP0354729A2 (en) * 1988-08-08 1990-02-14 Eli Lilly And Company Cytotoxic drug conjugates
WO1991013097A1 (en) * 1990-02-28 1991-09-05 Robin Ewart Offord Polyaminocarboxylic acid derivatives
EP0175617B1 (en) * 1984-09-13 1991-10-30 Cytogen Corporation Antibody-therapeutic agent conjugates
EP0476408A1 (en) * 1990-09-17 1992-03-25 Research Corporation Technologies, Inc. Chemical conjugation of morpholino anthracyclines to antibodies

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088695A2 (en) * 1982-03-09 1983-09-14 Cytogen Corporation Antibody conjugates
EP0175617B1 (en) * 1984-09-13 1991-10-30 Cytogen Corporation Antibody-therapeutic agent conjugates
EP0328147A2 (en) * 1988-02-11 1989-08-16 Bristol-Myers Squibb Company Anthracycline immunoconjugates having a novel linker and methods for their production
EP0354728A2 (en) * 1988-08-08 1990-02-14 Eli Lilly And Company Cytotoxic drug conjugates
EP0354729A2 (en) * 1988-08-08 1990-02-14 Eli Lilly And Company Cytotoxic drug conjugates
WO1991013097A1 (en) * 1990-02-28 1991-09-05 Robin Ewart Offord Polyaminocarboxylic acid derivatives
EP0476408A1 (en) * 1990-09-17 1992-03-25 Research Corporation Technologies, Inc. Chemical conjugation of morpholino anthracyclines to antibodies

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