GR1006568B - Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου - Google Patents

Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου

Info

Publication number
GR1006568B
GR1006568B GR20080100282A GR20080100282A GR1006568B GR 1006568 B GR1006568 B GR 1006568B GR 20080100282 A GR20080100282 A GR 20080100282A GR 20080100282 A GR20080100282 A GR 20080100282A GR 1006568 B GR1006568 B GR 1006568B
Authority
GR
Greece
Prior art keywords
regeneration
nerve
recording
electronic unit
aiding
Prior art date
Application number
GR20080100282A
Other languages
English (en)
Inventor
Αλεξανδρος Μπερης
Original Assignee
Αλεξανδρος Μπερης
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Αλεξανδρος Μπερης filed Critical Αλεξανδρος Μπερης
Priority to GR20080100282A priority Critical patent/GR1006568B/el
Priority to EP09734126A priority patent/EP2307090A2/en
Priority to PCT/GR2009/000024 priority patent/WO2009130515A2/en
Publication of GR1006568B publication Critical patent/GR1006568B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cell Biology (AREA)
  • Electrotherapy Devices (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Prostheses (AREA)

Abstract

Μέθοδος και σύστημα για την καταγραφή και υποβοήθηση της αναγέννησης περιφερικών νεύρων μετά από τραυματισμό που περιλαμβάνουν ένα ηλεκτρόδιο διέγερσης που εμφυτεύεται στο κεντρικό τμήμα του νεύρου, τουλάχιστον ένα ηλεκτρόδιο καταγραφής που εμφυτεύεται στο περιφερικό τμήμα του νεύρου, μία εμφυτεύσιμη ηλεκτρονική μονάδα, μία εμφυτεύσιμη συσκευή απελευθέρωσης παραγόντων διέγερσης της αναγέννησης, όπως είναι μία μίκρο-αντλία, και μία υπολογιστική μονάδα που τοποθετείται κατά προτίμηση εξωσωματικά για την μεταφορά δεδομένων και ενέργειας στην ηλεκτρονική μονάδα. Τα ηλεκτρικά σήματα που παράγονται από το περιφερικό τμήμα του τραυματισμένου νεύρου, μετά από κατάλληλη ηλεκτρική διέγερση του κεντρικού τμήματος του, καταγράφονται σε διάφορες χρονικές στιγμές. Η ανάλυση των καταγεγραμμένων ηλεκτρικών σημάτων χρησιμοποιείται για την εκτίμηση της κατάστασης και προόδου των αναγεννούμενων νευραξόνων από την οποία εκτίμηση προσδιορίζονται διάφορες παράμετροι ελέγχου. Οι αναφερθείσες παράμετροι χρησιμοποιούνται από την ηλεκτρονική μονάδα με σκοπό να ρυθμίσει την απελευθέρωση των παραγόντων διέγερσης κατά τρόπο ώστε η θεραπεία να είναι αποδοτική διατηρώντας παράλληλα τη χορήγηση των παραγόντων σε ασφαλή επίπεδα.
GR20080100282A 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου GR1006568B (el)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (el) 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου
EP09734126A EP2307090A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration
PCT/GR2009/000024 WO2009130515A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (el) 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου

Publications (1)

Publication Number Publication Date
GR1006568B true GR1006568B (el) 2009-10-13

Family

ID=40585045

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20080100282A GR1006568B (el) 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου

Country Status (3)

Country Link
EP (1) EP2307090A2 (el)
GR (1) GR1006568B (el)
WO (1) WO2009130515A2 (el)

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US9872990B2 (en) 2011-05-13 2018-01-23 Saluda Medical Pty Limited Method and apparatus for application of a neural stimulus
WO2012155188A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for controlling a neural stimulus - e
EP2707096B1 (en) 2011-05-13 2018-08-22 Saluda Medical Pty Limited Apparatus for measurement of neural response
WO2012155189A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for estimating neural recruitment - f
DK2707095T3 (en) 2011-05-13 2018-12-17 Saluda Medical Pty Ltd DEVICE FOR APPLYING A NEURAL STIMULUS
WO2012155190A1 (en) * 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for measurement of neural response
DK2908904T3 (da) 2012-11-06 2020-12-14 Saluda Medical Pty Ltd System til styring af vævs elektriske tilstand
DK2908905T3 (da) 2012-11-06 2020-12-14 Saluda Medical Pty Ltd System til at kontrollere elektriske forhold i væv
CN105848575B (zh) 2013-11-15 2019-11-19 萨鲁达医疗有限公司 监控大脑神经电位
WO2015074121A1 (en) 2013-11-22 2015-05-28 Saluda Medical Pty Ltd Method and device for detecting a neural response in a neural measurement
US20170135624A1 (en) 2014-03-28 2017-05-18 Saluda Medical Pty Ltd Assessing Neural State from Action Potentials
CA2944042C (en) 2014-05-05 2023-08-29 Saluda Medical Pty Ltd Improved neural measurement
JP2017524468A (ja) 2014-07-25 2017-08-31 サルーダ・メディカル・ピーティーワイ・リミテッド 神経刺激投与
US10597636B2 (en) 2014-09-19 2020-03-24 University Of Florida Research Foundation, Inc. Electroactive polymeric scaffolds and method for delivering nerve growth factor to nerve tissue
EP3215216B1 (en) 2014-11-17 2025-07-23 Saluda Medical Pty Ltd Method and device for detecting a neural response in neural measurements
AU2015362091B2 (en) 2014-12-11 2020-11-26 Saluda Medical Pty Ltd Method and device for feedback control of neural stimulation
US10588698B2 (en) 2014-12-11 2020-03-17 Saluda Medical Pty Ltd Implantable electrode positioning
US10918872B2 (en) 2015-01-19 2021-02-16 Saluda Medical Pty Ltd Method and device for neural implant communication
CN107530543B (zh) 2015-04-09 2021-03-02 萨鲁达医疗有限公司 电极到神经距离估计
EP3302258A4 (en) 2015-05-31 2018-11-21 Saluda Medical Pty Limited Monitoring brain neural activity
ES2989752T3 (es) 2015-05-31 2024-11-27 Closed Loop Medical Pty Ltd Ajuste de electrodos neuroestimuladores cerebrales
CA2980482C (en) 2015-06-01 2023-09-26 Saluda Medical Pty Ltd Motor fibre neuromodulation
CN109219467B (zh) 2016-04-05 2022-08-16 萨鲁达医疗有限公司 神经调节的经改进反馈控制
EP3474747B1 (en) 2016-06-24 2026-04-22 Saluda Medical Pty Ltd Neural stimulation for reduced artefact
WO2018144297A1 (en) 2017-02-01 2018-08-09 Avent, Inc. Emg guidance for probe placement, nearby tissue preservation, and lesion confirmation
WO2018232145A1 (en) * 2017-06-14 2018-12-20 Wichita State University Apparatus and method for neural regeneration
US10589089B2 (en) 2017-10-25 2020-03-17 Epineuron Technologies Inc. Systems and methods for delivering neuroregenerative therapy
CA3079849A1 (en) 2017-10-25 2019-05-02 Epineuron Technologies Inc. Systems and methods for delivering neuroregenerative therapy
JP2021521985A (ja) 2018-04-27 2021-08-30 サルーダ・メディカル・ピーティーワイ・リミテッド 混合神経の神経刺激
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Patent Citations (4)

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Also Published As

Publication number Publication date
WO2009130515A2 (en) 2009-10-29
WO2009130515A3 (en) 2010-04-01
EP2307090A2 (en) 2011-04-13

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Effective date: 20131104