GR1006568B - Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου - Google Patents

Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου

Info

Publication number
GR1006568B
GR1006568B GR20080100282A GR20080100282A GR1006568B GR 1006568 B GR1006568 B GR 1006568B GR 20080100282 A GR20080100282 A GR 20080100282A GR 20080100282 A GR20080100282 A GR 20080100282A GR 1006568 B GR1006568 B GR 1006568B
Authority
GR
Greece
Prior art keywords
regeneration
nerve
recording
electronic unit
aiding
Prior art date
Application number
GR20080100282A
Other languages
English (en)
Inventor
Αλεξανδρος Μπερης
Original Assignee
Αλεξανδρος Μπερης
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Αλεξανδρος Μπερης filed Critical Αλεξανδρος Μπερης
Priority to GR20080100282A priority Critical patent/GR1006568B/el
Priority to EP09734126A priority patent/EP2307090A2/en
Priority to PCT/GR2009/000024 priority patent/WO2009130515A2/en
Publication of GR1006568B publication Critical patent/GR1006568B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Prostheses (AREA)

Abstract

Μέθοδος και σύστημα για την καταγραφή και υποβοήθηση της αναγέννησης περιφερικών νεύρων μετά από τραυματισμό που περιλαμβάνουν ένα ηλεκτρόδιο διέγερσης που εμφυτεύεται στο κεντρικό τμήμα του νεύρου, τουλάχιστον ένα ηλεκτρόδιο καταγραφής που εμφυτεύεται στο περιφερικό τμήμα του νεύρου, μία εμφυτεύσιμη ηλεκτρονική μονάδα, μία εμφυτεύσιμη συσκευή απελευθέρωσης παραγόντων διέγερσης της αναγέννησης, όπως είναι μία μίκρο-αντλία, και μία υπολογιστική μονάδα που τοποθετείται κατά προτίμηση εξωσωματικά για την μεταφορά δεδομένων και ενέργειας στην ηλεκτρονική μονάδα. Τα ηλεκτρικά σήματα που παράγονται από το περιφερικό τμήμα του τραυματισμένου νεύρου, μετά από κατάλληλη ηλεκτρική διέγερση του κεντρικού τμήματος του, καταγράφονται σε διάφορες χρονικές στιγμές. Η ανάλυση των καταγεγραμμένων ηλεκτρικών σημάτων χρησιμοποιείται για την εκτίμηση της κατάστασης και προόδου των αναγεννούμενων νευραξόνων από την οποία εκτίμηση προσδιορίζονται διάφορες παράμετροι ελέγχου. Οι αναφερθείσες παράμετροι χρησιμοποιούνται από την ηλεκτρονική μονάδα με σκοπό να ρυθμίσει την απελευθέρωση των παραγόντων διέγερσης κατά τρόπο ώστε η θεραπεία να είναι αποδοτική διατηρώντας παράλληλα τη χορήγηση των παραγόντων σε ασφαλή επίπεδα.
GR20080100282A 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου GR1006568B (el)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (el) 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου
EP09734126A EP2307090A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration
PCT/GR2009/000024 WO2009130515A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (el) 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου

Publications (1)

Publication Number Publication Date
GR1006568B true GR1006568B (el) 2009-10-13

Family

ID=40585045

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20080100282A GR1006568B (el) 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου

Country Status (3)

Country Link
EP (1) EP2307090A2 (el)
GR (1) GR1006568B (el)
WO (1) WO2009130515A2 (el)

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US9974455B2 (en) 2011-05-13 2018-05-22 Saluda Medical Pty Ltd. Method and apparatus for estimating neural recruitment
WO2012155190A1 (en) * 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for measurement of neural response
US9872990B2 (en) 2011-05-13 2018-01-23 Saluda Medical Pty Limited Method and apparatus for application of a neural stimulus
WO2012155185A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for measurement of neural response
EP3434324B1 (en) 2011-05-13 2022-11-02 Saluda Medical Pty Ltd Device for application of a neural stimulus
DK3357533T3 (da) 2011-05-13 2021-11-15 Saluda Medical Pty Ltd Apparat til kontrol af en neural stimulus
US9386934B2 (en) 2011-05-13 2016-07-12 Saluda Medical Pty Ltd. Method and apparatus for measurement of neural response
DK2908904T3 (da) 2012-11-06 2020-12-14 Saluda Medical Pty Ltd System til styring af vævs elektriske tilstand
WO2014071446A1 (en) 2012-11-06 2014-05-15 Saluda Medical Pty Ltd Method and system for controlling electrical conditions of tissue ii
ES3033225T3 (en) 2013-11-15 2025-07-31 Closed Loop Medical Pty Ltd Monitoring brain neural potentials
CA2929874C (en) 2013-11-22 2023-06-13 Saluda Medical Pty Ltd Method and device for detecting a neural response in a neural measurement
EP3122247B1 (en) 2014-03-28 2025-05-07 Saluda Medical Pty Ltd Assessing neural state from action potentials
WO2015168735A1 (en) 2014-05-05 2015-11-12 Saluda Medical Pty Ltd Improved neural measurement
EP3838331B1 (en) 2014-07-25 2024-05-22 Saluda Medical Pty Limited Neural stimulation dosing
US10597636B2 (en) 2014-09-19 2020-03-24 University Of Florida Research Foundation, Inc. Electroactive polymeric scaffolds and method for delivering nerve growth factor to nerve tissue
US11006846B2 (en) 2014-11-17 2021-05-18 Saluda Medical Pty Ltd Method and device for detecting a neural response in neural measurements
AU2015362091B2 (en) 2014-12-11 2020-11-26 Saluda Medical Pty Ltd Method and device for feedback control of neural stimulation
WO2016090420A1 (en) 2014-12-11 2016-06-16 Saluda Medical Pty Ltd Implantable electrode positioning
WO2016115596A1 (en) 2015-01-19 2016-07-28 Saluda Medical Pty Ltd Method and device for neural implant communication
EP3280487B1 (en) 2015-04-09 2021-09-15 Saluda Medical Pty Limited Electrode to nerve distance estimation
JP7071257B2 (ja) 2015-05-31 2022-05-18 クローズド・ループ・メディカル・ピーティーワイ・リミテッド 脳神経刺激装置電極の取付け
CN107613860B (zh) 2015-05-31 2022-01-11 闭环医疗私人有限公司 脑神经活动监测
AU2016269843B2 (en) 2015-06-01 2021-03-04 Closed Loop Medical Pty Ltd Motor fibre neuromodulation
AU2017246242B2 (en) 2016-04-05 2022-06-23 Saluda Medical Pty Ltd Improved feedback control of neuromodulation
WO2017219096A1 (en) 2016-06-24 2017-12-28 Saluda Medical Pty Ltd Neural stimulation for reduced artefact
WO2018144297A1 (en) 2017-02-01 2018-08-09 Avent, Inc. Emg guidance for probe placement, nearby tissue preservation, and lesion confirmation
WO2018232145A1 (en) * 2017-06-14 2018-12-20 Wichita State University Apparatus and method for neural regeneration
US10589089B2 (en) 2017-10-25 2020-03-17 Epineuron Technologies Inc. Systems and methods for delivering neuroregenerative therapy
EP3700617A4 (en) 2017-10-25 2021-08-04 Epineuron Technologies Inc. SYSTEMS AND METHODS FOR ADMINISTERING NEUROR-REGENERATIVE THERAPY
ES2993811T3 (en) 2018-04-27 2025-01-09 Saluda Medical Pty Ltd Neurostimulation of mixed nerves
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Patent Citations (4)

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Also Published As

Publication number Publication date
WO2009130515A3 (en) 2010-04-01
EP2307090A2 (en) 2011-04-13
WO2009130515A2 (en) 2009-10-29

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Effective date: 20131104