GR1006568B - Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου - Google Patents

Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου

Info

Publication number
GR1006568B
GR1006568B GR20080100282A GR20080100282A GR1006568B GR 1006568 B GR1006568 B GR 1006568B GR 20080100282 A GR20080100282 A GR 20080100282A GR 20080100282 A GR20080100282 A GR 20080100282A GR 1006568 B GR1006568 B GR 1006568B
Authority
GR
Greece
Prior art keywords
regeneration
nerve
recording
electronic unit
aiding
Prior art date
Application number
GR20080100282A
Other languages
English (en)
Inventor
Αλεξανδρος Μπερης
Original Assignee
Αλεξανδρος Μπερης
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Αλεξανδρος Μπερης filed Critical Αλεξανδρος Μπερης
Priority to GR20080100282A priority Critical patent/GR1006568B/el
Priority to EP09734126A priority patent/EP2307090A2/en
Priority to PCT/GR2009/000024 priority patent/WO2009130515A2/en
Publication of GR1006568B publication Critical patent/GR1006568B/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A61N1/0556—Cuff electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Electrotherapy Devices (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Prostheses (AREA)

Abstract

Μέθοδος και σύστημα για την καταγραφή και υποβοήθηση της αναγέννησης περιφερικών νεύρων μετά από τραυματισμό που περιλαμβάνουν ένα ηλεκτρόδιο διέγερσης που εμφυτεύεται στο κεντρικό τμήμα του νεύρου, τουλάχιστον ένα ηλεκτρόδιο καταγραφής που εμφυτεύεται στο περιφερικό τμήμα του νεύρου, μία εμφυτεύσιμη ηλεκτρονική μονάδα, μία εμφυτεύσιμη συσκευή απελευθέρωσης παραγόντων διέγερσης της αναγέννησης, όπως είναι μία μίκρο-αντλία, και μία υπολογιστική μονάδα που τοποθετείται κατά προτίμηση εξωσωματικά για την μεταφορά δεδομένων και ενέργειας στην ηλεκτρονική μονάδα. Τα ηλεκτρικά σήματα που παράγονται από το περιφερικό τμήμα του τραυματισμένου νεύρου, μετά από κατάλληλη ηλεκτρική διέγερση του κεντρικού τμήματος του, καταγράφονται σε διάφορες χρονικές στιγμές. Η ανάλυση των καταγεγραμμένων ηλεκτρικών σημάτων χρησιμοποιείται για την εκτίμηση της κατάστασης και προόδου των αναγεννούμενων νευραξόνων από την οποία εκτίμηση προσδιορίζονται διάφορες παράμετροι ελέγχου. Οι αναφερθείσες παράμετροι χρησιμοποιούνται από την ηλεκτρονική μονάδα με σκοπό να ρυθμίσει την απελευθέρωση των παραγόντων διέγερσης κατά τρόπο ώστε η θεραπεία να είναι αποδοτική διατηρώντας παράλληλα τη χορήγηση των παραγόντων σε ασφαλή επίπεδα.
GR20080100282A 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου GR1006568B (el)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (el) 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου
EP09734126A EP2307090A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration
PCT/GR2009/000024 WO2009130515A2 (en) 2008-04-22 2009-04-15 Method and system for recording and promoting peripheral nerve regeneration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20080100282A GR1006568B (el) 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου

Publications (1)

Publication Number Publication Date
GR1006568B true GR1006568B (el) 2009-10-13

Family

ID=40585045

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20080100282A GR1006568B (el) 2008-04-22 2008-04-22 Μεθοδος και συστημα για την καταγραφη και υποβοηθηση της αναγεννησης περιφερικου νευρου

Country Status (3)

Country Link
EP (1) EP2307090A2 (el)
GR (1) GR1006568B (el)
WO (1) WO2009130515A2 (el)

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EP3434324B1 (en) 2011-05-13 2022-11-02 Saluda Medical Pty Ltd Device for application of a neural stimulus
WO2012155185A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for measurement of neural response
EP3357533B1 (en) 2011-05-13 2021-08-11 Saluda Medical Pty Ltd Apparatus for controlling a neural stimulus
US10588524B2 (en) * 2011-05-13 2020-03-17 Saluda Medical Pty Ltd Method and apparatus for measurement of neural response
JP6096759B2 (ja) 2011-05-13 2017-03-15 サルーダ・メディカル・ピーティーワイ・リミテッド 神経応答の測定のための方法および装置
WO2012155189A1 (en) 2011-05-13 2012-11-22 National Ict Australia Ltd Method and apparatus for estimating neural recruitment - f
US9872990B2 (en) 2011-05-13 2018-01-23 Saluda Medical Pty Limited Method and apparatus for application of a neural stimulus
AU2013344311B2 (en) 2012-11-06 2017-11-30 Saluda Medical Pty Ltd Method and system for controlling electrical conditions of tissue
ES2836792T3 (es) 2012-11-06 2021-06-28 Saluda Medical Pty Ltd Sistema para controlar las condiciones eléctricas de un tejido
AU2014351064B2 (en) 2013-11-15 2019-07-04 Closed Loop Medical Pty Ltd Monitoring brain neural potentials
CA2929874C (en) 2013-11-22 2023-06-13 Saluda Medical Pty Ltd Method and device for detecting a neural response in a neural measurement
WO2015143509A1 (en) 2014-03-28 2015-10-01 Saluda Medical Pty Ltd Assessing neural state from action potentials
WO2015168735A1 (en) 2014-05-05 2015-11-12 Saluda Medical Pty Ltd Improved neural measurement
DK3171929T3 (da) 2014-07-25 2021-05-25 Saluda Medical Pty Ltd Dosering til nervestimulation
US10597636B2 (en) 2014-09-19 2020-03-24 University Of Florida Research Foundation, Inc. Electroactive polymeric scaffolds and method for delivering nerve growth factor to nerve tissue
AU2015349614B2 (en) 2014-11-17 2020-10-22 Saluda Medical Pty Ltd Method and device for detecting a neural response in neural measurements
EP3218046B1 (en) 2014-12-11 2024-04-17 Saluda Medical Pty Ltd Device and computer program for feedback control of neural stimulation
US10588698B2 (en) 2014-12-11 2020-03-17 Saluda Medical Pty Ltd Implantable electrode positioning
AU2016208972B2 (en) 2015-01-19 2021-06-24 Saluda Medical Pty Ltd Method and device for neural implant communication
WO2016161484A2 (en) 2015-04-09 2016-10-13 Saluda Medical Pty Ltd Electrode to nerve distance estimation
WO2016191807A1 (en) 2015-05-31 2016-12-08 Saluda Medical Pty Ltd Brain neurostimulator electrode fitting
CA2983336C (en) 2015-05-31 2024-05-28 Saluda Medical Pty Ltd Monitoring brain neural activity
JP7204325B2 (ja) 2015-06-01 2023-01-16 クローズド・ループ・メディカル・ピーティーワイ・リミテッド 運動線維ニューロモジュレーション
US11191966B2 (en) 2016-04-05 2021-12-07 Saluda Medical Pty Ltd Feedback control of neuromodulation
EP3474747B1 (en) 2016-06-24 2026-04-22 Saluda Medical Pty Ltd Neural stimulation for reduced artefact
ES3009730T3 (en) 2017-02-01 2025-03-31 Avent Inc Emg guidance for probe placement, nearby tissue preservation, and lesion confirmation
WO2018232145A1 (en) * 2017-06-14 2018-12-20 Wichita State University Apparatus and method for neural regeneration
WO2019084182A1 (en) 2017-10-25 2019-05-02 Epineuron Technologies Inc. SYSTEMS AND METHODS FOR ADMINISTERING NEURODEGENERATIVE THERAPY
US10589089B2 (en) 2017-10-25 2020-03-17 Epineuron Technologies Inc. Systems and methods for delivering neuroregenerative therapy
EP4434461A3 (en) 2018-04-27 2025-03-05 Saluda Medical Pty Ltd Neurostimulation of mixed nerves
US11247043B2 (en) 2019-10-01 2022-02-15 Epineuron Technologies Inc. Electrode interface devices for delivery of neuroregenerative therapy

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Patent Citations (4)

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Also Published As

Publication number Publication date
WO2009130515A3 (en) 2010-04-01
EP2307090A2 (en) 2011-04-13
WO2009130515A2 (en) 2009-10-29

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Effective date: 20131104