GR1007628B - Φαρμακευτικο σκευασμα περιεχον εναν αντιμουσκαρινικο παραγοντα και μεθοδος για την παρασκευη αυτου - Google Patents
Φαρμακευτικο σκευασμα περιεχον εναν αντιμουσκαρινικο παραγοντα και μεθοδος για την παρασκευη αυτουInfo
- Publication number
- GR1007628B GR1007628B GR20110100444A GR20110100444A GR1007628B GR 1007628 B GR1007628 B GR 1007628B GR 20110100444 A GR20110100444 A GR 20110100444A GR 20110100444 A GR20110100444 A GR 20110100444A GR 1007628 B GR1007628 B GR 1007628B
- Authority
- GR
- Greece
- Prior art keywords
- preparation
- pharmaceutical composition
- antimuscarinic agent
- composition containing
- coating layer
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000003149 muscarinic antagonist Substances 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000011247 coating layer Substances 0.000 abstract 2
- 230000002496 gastric effect Effects 0.000 abstract 1
- 229920001600 hydrophobic polymer Polymers 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- OOGJQPCLVADCPB-HXUWFJFHSA-N tolterodine Chemical compound C1([C@@H](CCN(C(C)C)C(C)C)C=2C(=CC=C(C)C=2)O)=CC=CC=C1 OOGJQPCLVADCPB-HXUWFJFHSA-N 0.000 abstract 1
- 229960004045 tolterodine Drugs 0.000 abstract 1
- BDIAUFOIMFAIPU-UHFFFAOYSA-N valepotriate Natural products CC(C)CC(=O)OC1C=C(C(=COC2OC(=O)CC(C)C)COC(C)=O)C2C11CO1 BDIAUFOIMFAIPU-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Η παρούσα εφεύρεση αφορά αφενός φαρμακοτεχνική σύνθεση τροποποιημένης αποδέσμευσης για χορήγηση διά στόματος, η οποία περιέχει ως δραστική ουσία ποσότητα ενός αντιμουσκαρινικού παράγοντα όπως η Τολτεροδίνη ή κάποιο φαρμακευτικά αποδεκτό άλας, παράγωγο, προφάρμακο ή μεταβολίτη αυτής, που εσωκλείεται στον πυρήνα μιας μήτρας, ο οποίος πυρήνας επικαλύπτεται με μια πρώτη στρώση ενός υδρόφοβου πολυμερούς και μια δεύτερη στρώση ενός πολυμερούς ανθεκτικού στο γαστρικό ρΗ και αφετέρου τη μέθοδο παρασκευής αυτής της σύνθεσης.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20110100444A GR1007628B (el) | 2011-07-27 | 2011-07-27 | Φαρμακευτικο σκευασμα περιεχον εναν αντιμουσκαρινικο παραγοντα και μεθοδος για την παρασκευη αυτου |
| EP12751445.3A EP2736496B1 (en) | 2011-07-27 | 2012-07-20 | Pharmaceutical composition containing an antimuscarinic agent and method for the preparation thereof |
| DK12751445.3T DK2736496T3 (en) | 2011-07-27 | 2012-07-20 | PHARMACEUTICAL COMPOSITION CONTAINING AN ANTI-MUSCARINE AND PROCEDURE FOR PREPARING THEREOF |
| PCT/EP2012/003076 WO2013013798A1 (en) | 2011-07-27 | 2012-07-20 | Pharmaceutical composition containing an antimuscarinic agent and method for the preparation thereof |
| ES12751445T ES2697609T3 (es) | 2011-07-27 | 2012-07-20 | Composición farmacéutica que contiene un agente antimuscarínico y método para la preparación del mismo |
| PL12751445T PL2736496T3 (pl) | 2011-07-27 | 2012-07-20 | Kompozycja farmaceutyczna zawierająca środek przeciwmuskarynowy i sposób jej wytwarzania |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20110100444A GR1007628B (el) | 2011-07-27 | 2011-07-27 | Φαρμακευτικο σκευασμα περιεχον εναν αντιμουσκαρινικο παραγοντα και μεθοδος για την παρασκευη αυτου |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR1007628B true GR1007628B (el) | 2012-06-29 |
Family
ID=45814524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20110100444A GR1007628B (el) | 2011-07-27 | 2011-07-27 | Φαρμακευτικο σκευασμα περιεχον εναν αντιμουσκαρινικο παραγοντα και μεθοδος για την παρασκευη αυτου |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2736496B1 (el) |
| DK (1) | DK2736496T3 (el) |
| ES (1) | ES2697609T3 (el) |
| GR (1) | GR1007628B (el) |
| PL (1) | PL2736496T3 (el) |
| WO (1) | WO2013013798A1 (el) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015022703A1 (en) * | 2013-08-12 | 2015-02-19 | Genepharm India Private Limited | A stable pharmaceutical composition of fesoterodine hydrochloride |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1731142A1 (en) * | 2005-06-08 | 2006-12-13 | Dexcel Pharma Technologies Ltd. | Specific time-delayed burst profile delivery system |
| EP1810668A1 (en) * | 2006-01-23 | 2007-07-25 | LEK Pharmaceuticals D.D. | Coated formulations containing tolterodine tartrate |
| US20090214665A1 (en) * | 2008-02-26 | 2009-08-27 | Lai Felix S | Controlled Release Muscarinic Receptor Antagonist Formulation |
| WO2010096820A1 (en) * | 2009-02-23 | 2010-08-26 | Eurand, Inc. | Controlled release compositions comprising anti-cholinergic drugs |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9803871D0 (sv) | 1998-11-11 | 1998-11-11 | Pharmacia & Upjohn Ab | Therapeutic method and formulation |
| WO2005105036A1 (en) * | 2004-04-28 | 2005-11-10 | Natco Pharma Limited | Controlled release mucoadhesive matrix formulation containing tolterodine and a process for its preparation |
| WO2007029087A2 (en) | 2005-09-05 | 2007-03-15 | Ranbaxy Laboratories Limited | Controlled release multiple unit formulations |
| WO2007122015A1 (en) | 2006-04-21 | 2007-11-01 | Synthon B.V. | Tolterodine beads |
-
2011
- 2011-07-27 GR GR20110100444A patent/GR1007628B/el not_active IP Right Cessation
-
2012
- 2012-07-20 DK DK12751445.3T patent/DK2736496T3/en active
- 2012-07-20 EP EP12751445.3A patent/EP2736496B1/en not_active Not-in-force
- 2012-07-20 WO PCT/EP2012/003076 patent/WO2013013798A1/en not_active Ceased
- 2012-07-20 PL PL12751445T patent/PL2736496T3/pl unknown
- 2012-07-20 ES ES12751445T patent/ES2697609T3/es active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1731142A1 (en) * | 2005-06-08 | 2006-12-13 | Dexcel Pharma Technologies Ltd. | Specific time-delayed burst profile delivery system |
| EP1810668A1 (en) * | 2006-01-23 | 2007-07-25 | LEK Pharmaceuticals D.D. | Coated formulations containing tolterodine tartrate |
| US20090214665A1 (en) * | 2008-02-26 | 2009-08-27 | Lai Felix S | Controlled Release Muscarinic Receptor Antagonist Formulation |
| WO2010096820A1 (en) * | 2009-02-23 | 2010-08-26 | Eurand, Inc. | Controlled release compositions comprising anti-cholinergic drugs |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2736496B1 (en) | 2018-09-05 |
| ES2697609T3 (es) | 2019-01-25 |
| PL2736496T3 (pl) | 2019-02-28 |
| EP2736496A1 (en) | 2014-06-04 |
| WO2013013798A1 (en) | 2013-01-31 |
| DK2736496T3 (en) | 2019-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PG | Patent granted |
Effective date: 20120713 |
|
| ML | Lapse due to non-payment of fees |
Effective date: 20170207 |