GR1011042B - Αντιικος παραγοντας με φυσικα συστατικα σε μορφη σπρεϊ για ρινικη εφαρμογη - Google Patents

Αντιικος παραγοντας με φυσικα συστατικα σε μορφη σπρεϊ για ρινικη εφαρμογη

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Publication number
GR1011042B
GR1011042B GR20240100470A GR20240100470A GR1011042B GR 1011042 B GR1011042 B GR 1011042B GR 20240100470 A GR20240100470 A GR 20240100470A GR 20240100470 A GR20240100470 A GR 20240100470A GR 1011042 B GR1011042 B GR 1011042B
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GR
Greece
Prior art keywords
virus particles
cov
entry
protective film
preventing
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Application number
GR20240100470A
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English (en)
Inventor
Δημητρης Γεωργιου Λαδικος
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Δημητρης Γεωργιου Λαδικος
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Application filed by Δημητρης Γεωργιου Λαδικος filed Critical Δημητρης Γεωργιου Λαδικος
Priority to GR20240100470A priority Critical patent/GR1011042B/el
Publication of GR1011042B publication Critical patent/GR1011042B/el

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/731Carrageenans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Η εφεύρεση αφορά τη σύνθεση και παρασκευή ενός προϊόντος σπρέι, το οποίο χαρακτηρίζεται από αντιικές ιδιότητες και εφαρμόζεται στη ρινική κοιλότητα. Το σπρέι λειτουργεί απωθώντας τα σωματίδια του ιού και παρεμποδίζοντας την αλληλεπίδραση των υποδοχέων του ξενιστή με τις ιικές πρωτεΐνες που είναι υπεύθυνες για την είσοδο των ιικών σωματιδίων στα ανθρώπινα κύτταρα. Τα αιθέρια έλαια ευκαλύπτου, κανέλας και λεβάντας είναι γνωστά για την αντιική τους δράση σε κατάσταση ατμού, επομένως έχουν επιλεγεί για να «παγιδεύουν» και να απωθούν τα ιικά σωματίδια πριν εισέλθουν στον ανθρώπινο οργανισμό. Επιπλέον, περιέχει ένα φυτικό συστατικό, το οποίο δημιουργεί ένα προστατευτικό φιλμ στο βλενογόννο της μύτης παρεμποδίζοντας την είσοδο των σωματιδίων του ιού στον ανθρώπινο οργανισμό. Συγκεκριμένα, περιέχει τα έλαια περγαμόντου και τεϊόδεντρου, τα οποία είναι γνωστά για την ανασταλτική του δράση κατά του SARS-CoV-2 και του Η1Ν1, επηρεάζοντας τις οδούς του μηχανισμού μόλυνσης. Επίσης, περιέχει αιθέριο έλαιο θυμαριού, που έχει ιοκτόνο δράση έναντι του SARS-CoV-2 και του ιού της γρίπης. Τέλος, για την δημιουργία του προστατευτικού φιλμ, που αναφέρθηκε παραπάνω, χρησιμοποιήθηκε η yota-carrageenan ένας θειικός πολυσακχαρίτης υψηλού μοριακού βάρους, που προέρχεται από κόκκινα φύκια (Rhodophyceae) και chitosan και ουλβάνες. Η σύνθεσή του στοχεύει κυρίως στον ιό της γρίπης τύπου Α και Β, σε ρινοϊούς και κορονοϊούς.
GR20240100470A 2024-06-30 2024-06-30 Αντιικος παραγοντας με φυσικα συστατικα σε μορφη σπρεϊ για ρινικη εφαρμογη GR1011042B (el)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GR20240100470A GR1011042B (el) 2024-06-30 2024-06-30 Αντιικος παραγοντας με φυσικα συστατικα σε μορφη σπρεϊ για ρινικη εφαρμογη

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20240100470A GR1011042B (el) 2024-06-30 2024-06-30 Αντιικος παραγοντας με φυσικα συστατικα σε μορφη σπρεϊ για ρινικη εφαρμογη

Publications (1)

Publication Number Publication Date
GR1011042B true GR1011042B (el) 2025-09-23

Family

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Family Applications (1)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040071757A1 (en) * 2001-11-20 2004-04-15 David Rolf Inhalation antiviral patch
US20060120967A1 (en) * 2004-12-07 2006-06-08 Qpharma, Llc Solution forms of cyclodextrins for nasal or throat delivery of essential oils
US20130156868A1 (en) * 2010-09-07 2013-06-20 Krewel Mueselbach GmbH Nasal spray
US20210315955A1 (en) * 2020-04-10 2021-10-14 Bert Forman Compositions and methods for treatment of respiratory ailments
WO2022099182A1 (en) * 2020-11-09 2022-05-12 Rucker Capital Advisors Oral rinse, nasal spray and methods for prevention of covid-19 by lowering viral load of covid-19
WO2023031929A1 (en) * 2021-08-31 2023-03-09 Polyrizon Ltd. Mucoadhesive polymers for nasal drug delivery
US20240058385A1 (en) * 2022-08-09 2024-02-22 Core Consumer Healthcare LLC Anti-viral compositions and methods

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040071757A1 (en) * 2001-11-20 2004-04-15 David Rolf Inhalation antiviral patch
US20060120967A1 (en) * 2004-12-07 2006-06-08 Qpharma, Llc Solution forms of cyclodextrins for nasal or throat delivery of essential oils
US20130156868A1 (en) * 2010-09-07 2013-06-20 Krewel Mueselbach GmbH Nasal spray
US20210315955A1 (en) * 2020-04-10 2021-10-14 Bert Forman Compositions and methods for treatment of respiratory ailments
WO2022099182A1 (en) * 2020-11-09 2022-05-12 Rucker Capital Advisors Oral rinse, nasal spray and methods for prevention of covid-19 by lowering viral load of covid-19
WO2023031929A1 (en) * 2021-08-31 2023-03-09 Polyrizon Ltd. Mucoadhesive polymers for nasal drug delivery
US20240058385A1 (en) * 2022-08-09 2024-02-22 Core Consumer Healthcare LLC Anti-viral compositions and methods

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Effective date: 20251009