GR18376B - METHOD OF PREPARATION OF MONOESTERS AND DIESTERS OF PENICILLIN. - Google Patents
METHOD OF PREPARATION OF MONOESTERS AND DIESTERS OF PENICILLIN.Info
- Publication number
- GR18376B GR18376B GR540118376A GR540118376A GR18376B GR 18376 B GR18376 B GR 18376B GR 540118376 A GR540118376 A GR 540118376A GR 540118376 A GR540118376 A GR 540118376A GR 18376 B GR18376 B GR 18376B
- Authority
- GR
- Greece
- Prior art keywords
- derived
- group
- groups
- penicillin
- conh
- Prior art date
Links
- 229930182555 Penicillin Natural products 0.000 title 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 title 1
- 150000005690 diesters Chemical class 0.000 title 1
- 229940049954 penicillin Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000006367 bivalent amino carbonyl group Chemical group [H]N([*:1])C([*:2])=O 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 150000007942 carboxylates Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- 150000002989 phenols Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
στέρες της πενικιλλίνης μετά φαινολών και θειουαινολών αχουσών ένα βασικόν υποκαταστάτην, και τα διά προσθήκης οξέων άλατα τούτων, ένθα οι ρηθέντες εστέρες παριστώνταια υπό του τύπου (Ι) ένθα το Z1 προέρχεται εκ της κατηγορίας ήτις αποτελείται από PenCOO και PenCOS, ένθα το PenCO παριστά πενικιλλίνην μεθ υδροξυλίου αφαιρεθέντος εκ της καρβοξυλικής ομάδος ένθα το Z2 προέρχεται εκ της κατηγορίας ήτις αποτελίται εξ υδρογόνου και των ομάδων αίτινεςπαριστώνται διά του Z1 ένθα το Υ προέρσεται έκ της κατηγορίας ήτις αποτελειται εξ αλκυλενικών ομάδων και αλυλενικών ομάδων συνδεδεμένων μεθ ενός ατόμου ανθρακος του φαινυλικού δακτυλίου διά μιάς εκ των ακολούθων ομάδων: -C-, -S-, -NH-, -NR-, -RC-, -RS-, -CE-, COO-, CONH-, -CONH-, -COS-, CSO-, NHCO-, NRXO-, NHCS-, NRCS-, CSNH-, CSNR-, ένθα το R είναι μία αλκυλική ομάς εξ 1 ή 2 ατόμων άνθρακος, καιένθα το R1 και R2 , προέρχονται εκ της κατηγορίας ήτις αποτελείται εξ αλκυλικών ομάδων μετά ουχί περισσοτέρων των 4 ατόμων άνθρακος, και αλυλενικώνομάδων σχηματιζουσών ένα ετεροκυκλικόν δακτύλιον μετο άτομον του αζωτου. penicillin esters after phenols and thioenols are a basic substituent, and the acid addition salts thereof, wherein said esters are represented by formula (I) wherein Z1 is derived from the class consisting of PenCOO and PenCOS, of hydroxyl removed from the carboxylate group wherein Z2 is derived from the group as it consists of hydrogen and the groups are represented by Z1 whereas Y is derived from the category as it consists of an alkylene group and an alkyl group attached to a of the following groups: -C-, -S-, -NH-, -NR-, -RC-, -RS-, -CE-, COO-, CONH-, -CONH-, -COS-, CSO-, NHCO-, NRXO-, NHCS-, NRCS-, CSNH-, CSNR-, wherein R is an alkyl group of 1 or 2 carbon atoms, whereas R1 and R2 are of the category as it consists of alkyl groups of no more than of 4 carbon atoms, and alylene atom forming a heterocyclic ring with a nitrogen atom.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR540118376A GR18376B (en) | 1954-08-10 | 1954-08-10 | METHOD OF PREPARATION OF MONOESTERS AND DIESTERS OF PENICILLIN. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR540118376A GR18376B (en) | 1954-08-10 | 1954-08-10 | METHOD OF PREPARATION OF MONOESTERS AND DIESTERS OF PENICILLIN. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR18376B true GR18376B (en) | 1957-12-19 |
Family
ID=36838485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR540118376A GR18376B (en) | 1954-08-10 | 1954-08-10 | METHOD OF PREPARATION OF MONOESTERS AND DIESTERS OF PENICILLIN. |
Country Status (1)
| Country | Link |
|---|---|
| GR (1) | GR18376B (en) |
-
1954
- 1954-08-10 GR GR540118376A patent/GR18376B/en unknown
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