GR20090100230A - Απο του στοματος εναιωρημα οξικης δεξαμεθανοζης-συνθεση καλυψης γευσης της δεξαμεθανοζης - Google Patents
Απο του στοματος εναιωρημα οξικης δεξαμεθανοζης-συνθεση καλυψης γευσης της δεξαμεθανοζηςInfo
- Publication number
- GR20090100230A GR20090100230A GR20090100230A GR20090100230A GR20090100230A GR 20090100230 A GR20090100230 A GR 20090100230A GR 20090100230 A GR20090100230 A GR 20090100230A GR 20090100230 A GR20090100230 A GR 20090100230A GR 20090100230 A GR20090100230 A GR 20090100230A
- Authority
- GR
- Greece
- Prior art keywords
- dexamethasone
- dexamethasone acetate
- bad taste
- pharmaceutically acceptable
- drastic
- Prior art date
Links
- FPVRUILUEYSIMD-RPRRAYFGSA-N [(8s,9r,10s,11s,13s,14s,16r,17r)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] acetate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(OC(C)=O)[C@@]1(C)C[C@@H]2O FPVRUILUEYSIMD-RPRRAYFGSA-N 0.000 title abstract 4
- 229960003657 dexamethasone acetate Drugs 0.000 title abstract 4
- 206010013911 Dysgeusia Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000873 masking effect Effects 0.000 title 1
- 229940100692 oral suspension Drugs 0.000 title 1
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 2
- 239000008135 aqueous vehicle Substances 0.000 abstract 2
- 229960003957 dexamethasone Drugs 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
- -1 dexamethasone ester Chemical class 0.000 abstract 1
- 239000010419 fine particle Substances 0.000 abstract 1
- 235000011187 glycerol Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 229940124531 pharmaceutical excipient Drugs 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20090100230A GR20090100230A (el) | 2009-04-14 | 2009-04-14 | Απο του στοματος εναιωρημα οξικης δεξαμεθανοζης-συνθεση καλυψης γευσης της δεξαμεθανοζης |
| EP10719774A EP2477604A2 (fr) | 2009-04-14 | 2010-04-14 | Suspension d'acétate de dexaméthasone à usage oral composition masquant le goût de la dexaméthasone |
| PCT/GR2010/000018 WO2010119300A2 (fr) | 2009-04-14 | 2010-04-14 | Suspension d'acétate de dexaméthasone à usage oral – composition masquant le goût de la dexaméthasone |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR20090100230A GR20090100230A (el) | 2009-04-14 | 2009-04-14 | Απο του στοματος εναιωρημα οξικης δεξαμεθανοζης-συνθεση καλυψης γευσης της δεξαμεθανοζης |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR20090100230A true GR20090100230A (el) | 2010-11-18 |
Family
ID=42269791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20090100230A GR20090100230A (el) | 2009-04-14 | 2009-04-14 | Απο του στοματος εναιωρημα οξικης δεξαμεθανοζης-συνθεση καλυψης γευσης της δεξαμεθανοζης |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2477604A2 (fr) |
| GR (1) | GR20090100230A (fr) |
| WO (1) | WO2010119300A2 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101368587B1 (ko) * | 2010-12-27 | 2014-03-05 | 주식회사 삼양바이오팜 | 오심 또는 구토 방지용 조성물 |
| WO2013149258A2 (fr) | 2012-03-30 | 2013-10-03 | Charles Drew University of Medicine and Science | Compositions et procédés de traitement ou de prévention de troubles du syndrome métabolique |
| US20140271923A1 (en) | 2013-03-14 | 2014-09-18 | Christopher Brian Reid | Compositions & formulations for preventing and treating chronic diseases that cluster in patients such as cardiovascular disease, diabetes, obesity, polycystic ovary syndrome, hyperlipidemia and hypertension, as well as for preventing and treating other diseases and conditions |
| US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2159195A1 (en) | 1971-11-10 | 1973-06-22 | Fabre Sa Pierre | Compsns contg sorbitol and a corticoid or pyrazolone - - suppression of ulcerogenic effects |
| US3962430A (en) | 1974-08-07 | 1976-06-08 | Merck & Co., Inc. | Sterilization of solid non-electrolyte medicinal agents employing sodium chloride |
| US6066292A (en) * | 1997-12-19 | 2000-05-23 | Bayer Corporation | Sterilization process for pharmaceutical suspensions |
| JP2007533697A (ja) | 2004-04-22 | 2007-11-22 | デュオコート エービー | グルココルチコイド救急治療用の医薬組成物 |
| JP5607291B2 (ja) | 2004-11-24 | 2014-10-15 | メダ ファーマシューティカルズ インコーポレイテッド | アゼラスチンを含む組成物およびその使用方法 |
| JP5002462B2 (ja) | 2004-12-09 | 2012-08-15 | バイエル・アニマル・ヘルス・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 酸によるグルココルチコイドエステルの安定化 |
| DE102005055385A1 (de) | 2004-12-09 | 2006-06-14 | Bayer Healthcare Ag | Arzneimittel zur hygienischen Applikation im Ohr |
| US8468589B2 (en) | 2006-01-13 | 2013-06-18 | Fortinet, Inc. | Computerized system and method for advanced network content processing |
| CA2630304C (fr) | 2005-12-09 | 2012-04-10 | Teva Pharmaceutical Industries Ltd. | Solutions et dispersions aqueuses de composes difficiles a dissoudre et leurs procedes de preparation |
| CN101190177B (zh) * | 2006-11-24 | 2010-09-01 | 上海医药工业研究院 | 醋酸地塞米松局部成膜凝胶组合物及其应用 |
-
2009
- 2009-04-14 GR GR20090100230A patent/GR20090100230A/el active IP Right Revival
-
2010
- 2010-04-14 EP EP10719774A patent/EP2477604A2/fr not_active Withdrawn
- 2010-04-14 WO PCT/GR2010/000018 patent/WO2010119300A2/fr not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010119300A3 (fr) | 2011-03-24 |
| WO2010119300A2 (fr) | 2010-10-21 |
| EP2477604A2 (fr) | 2012-07-25 |
| WO2010119300A9 (fr) | 2011-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MF | Right revoked (revocation) |
Effective date: 20111107 |
|
| ML | Lapse due to non-payment of fees |
Effective date: 20111102 |
|
| ML | Lapse due to non-payment of fees |
Effective date: 20121102 |
|
| NF | Restoration of lapsed right |
Effective date: 20120117 |