GR20125B - METHOD FOR THE PRODUCTION OF 4 - HYDROXY - 17 - A - METHYLOTESTERONE AND OF THERE ESTERS. - Google Patents

METHOD FOR THE PRODUCTION OF 4 - HYDROXY - 17 - A - METHYLOTESTERONE AND OF THERE ESTERS.

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Publication number
GR20125B
GR20125B GR590120125A GR590120125A GR20125B GR 20125 B GR20125 B GR 20125B GR 590120125 A GR590120125 A GR 590120125A GR 590120125 A GR590120125 A GR 590120125A GR 20125 B GR20125 B GR 20125B
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GR
Greece
Prior art keywords
methylotesterone
hydroxy
esters
production
methyltestosterone
Prior art date
Application number
GR590120125A
Other languages
Greek (el)
Inventor
Bruno Camerino
Biancce Patelli
Giovanni Sala
Original Assignee
Societa Farmaceutici Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societa Farmaceutici Italia filed Critical Societa Farmaceutici Italia
Priority to GR590120125A priority Critical patent/GR20125B/en
Publication of GR20125B publication Critical patent/GR20125B/en

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Abstract

έθοδος δια την σύνθεσιν ενώσεων εχουσών μεγάλην αναβολικήν δραστηκότητα κατά την δια στόματος χορήγησιν, του γενικού τύπου: [*] εν τω οποίω το R είναι υδρογόνον ή COR' και το R' είναι αλκύλιον με ουχί περισσότερα των 9 ατόμων άνθρακος, περιλαμβάνουσα κατεργασίαν μιας 4,5-διϋδροξει-17α-μεθυλοτεστοστερόνης δια διαλύματος υδατικού/αλκοολικού ΚΟΗ και κατεργασίαν της λαμβανομένης 4-υδροξει-17α-μεθυλοτεστοστερόνης δια του χλωρούχου άλατος ή του ανυδρίτου ενός καρβοξυλικού οξέος με όχι περισσότερα των9 ατόμων άνθρακος, παρουσία ή απουσία μιας τριτογενούς βάσεως. (Προτεραιότης της 6.5.59). Method for the synthesis of compounds having high anabolic activity during oral administration, of the general formula: [*] wherein R is hydrogen or COR 'and R' is alkyl of not more than 9 carbon atoms, comprising treating a 4,5-dihydroxy-17α-methyltestosterone with an aqueous / alcoholic KOH solution and treating the obtained 4-hydro 17α-methyltestosterone by the chloride or anhydride of a carboxylic acid having not more than 9 carbon atoms, in the presence or absence of a tertiary base. (Priority of 6.5.59).

GR590120125A 1959-06-01 1959-06-01 METHOD FOR THE PRODUCTION OF 4 - HYDROXY - 17 - A - METHYLOTESTERONE AND OF THERE ESTERS. GR20125B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GR590120125A GR20125B (en) 1959-06-01 1959-06-01 METHOD FOR THE PRODUCTION OF 4 - HYDROXY - 17 - A - METHYLOTESTERONE AND OF THERE ESTERS.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR590120125A GR20125B (en) 1959-06-01 1959-06-01 METHOD FOR THE PRODUCTION OF 4 - HYDROXY - 17 - A - METHYLOTESTERONE AND OF THERE ESTERS.

Publications (1)

Publication Number Publication Date
GR20125B true GR20125B (en) 1959-09-28

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ID=36861221

Family Applications (1)

Application Number Title Priority Date Filing Date
GR590120125A GR20125B (en) 1959-06-01 1959-06-01 METHOD FOR THE PRODUCTION OF 4 - HYDROXY - 17 - A - METHYLOTESTERONE AND OF THERE ESTERS.

Country Status (1)

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GR (1) GR20125B (en)

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