GR3003305T3 - Inhibition of post-surgical adhesion formation by the topical administration of tissue plasminogen activator - Google Patents

Inhibition of post-surgical adhesion formation by the topical administration of tissue plasminogen activator

Info

Publication number
GR3003305T3
GR3003305T3 GR91401929T GR910401929T GR3003305T3 GR 3003305 T3 GR3003305 T3 GR 3003305T3 GR 91401929 T GR91401929 T GR 91401929T GR 910401929 T GR910401929 T GR 910401929T GR 3003305 T3 GR3003305 T3 GR 3003305T3
Authority
GR
Greece
Prior art keywords
inhibition
post
topical administration
plasminogen activator
tissue plasminogen
Prior art date
Application number
GR91401929T
Other languages
English (en)
Inventor
Warren D Sheffield
Gere D Dizerega
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Inc filed Critical Ethicon Inc
Publication of GR3003305T3 publication Critical patent/GR3003305T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR91401929T 1985-12-16 1991-12-11 Inhibition of post-surgical adhesion formation by the topical administration of tissue plasminogen activator GR3003305T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80953685A 1985-12-16 1985-12-16

Publications (1)

Publication Number Publication Date
GR3003305T3 true GR3003305T3 (en) 1993-02-17

Family

ID=25201563

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91401929T GR3003305T3 (en) 1985-12-16 1991-12-11 Inhibition of post-surgical adhesion formation by the topical administration of tissue plasminogen activator

Country Status (8)

Country Link
EP (1) EP0227400B1 (el)
JP (1) JPH0764749B2 (el)
KR (1) KR870005646A (el)
AU (1) AU586306B2 (el)
CA (1) CA1297791C (el)
DE (1) DE3682754D1 (el)
GR (1) GR3003305T3 (el)
ZA (1) ZA869434B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0131330B1 (ko) * 1987-07-01 1998-04-17 맥스 디. 헨슬레이 피브린 침착 또는 유착을 방지하기 위한 방법 및 치료 조성물
JPH021988A (ja) * 1987-12-03 1990-01-08 Texas Instr Inc <Ti> 電気的にプログラム可能なメモリ・セル
US5364622A (en) * 1987-12-04 1994-11-15 Dr. Karl Thomae Gmbh Methods for preventing adhesions to organs and parts of organs by application of tissue plasminogen activator and hydroxyethylcellulose hydrogel
DE3741149A1 (de) * 1987-12-04 1989-06-15 Thomae Gmbh Dr K Zubereitungsformen zur verhinderung von adhaesionen von organen und organteilen
ATE135200T1 (de) * 1989-05-17 1996-03-15 Res Corp Technologies Inc Verfahren und zusammensetzung zur thrombosebehandlung beim säugetier
NL9201722A (nl) * 1992-10-05 1994-05-02 Stichting Tech Wetenschapp Farmaceutische samenstelling voor de plaatsgebonden afgifte van een stolsel oplossend eiwit en werkwijze voor de bereiding daarvan.
DE69528573T2 (de) * 1995-01-27 2003-06-18 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno, Den Haag/S'gravenhage Verwendung einer Zubereitung enthaltend einen Plasminogen-Aktivator für die Verbesserung der Wundheilung
DE19529223A1 (de) * 1995-08-09 1997-02-13 Boehringer Mannheim Gmbh Verwendung von Plasminogenaktivatoren zum lokalen Knochenaufbau
EP0943332A1 (en) * 1998-03-19 1999-09-22 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Prevention and treatment of adhesions
CA2989941A1 (en) * 2004-09-23 2006-03-30 Arc Pharmaceuticals, Inc. Pharmaceutical compostions and methods relating to inhibiting fibrous adhesions or inflammatory disease using low sulphate fucans
DE102014112212A1 (de) 2014-08-26 2016-03-03 Akesion Gmbh Rekombinante Fusionsproteine zur Vorbeugung oder Behandlung von Adhäsionen bei Geweben oder Organen

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3755558A (en) * 1971-02-23 1973-08-28 Du Pont Polylactide drug mixtures for topical application atelet aggregation
AT359653B (de) * 1979-02-15 1980-11-25 Immuno Ag Verfahren zur herstellung eines gewebekleb- stoffes
FR2483234A2 (fr) * 1980-05-29 1981-12-04 Fabre Sa Pierre Composition ophtalmique contenant un activateur du plasminogene
GR79202B (el) * 1982-05-05 1984-10-22 Genentech Inc
JPS59160465A (ja) * 1983-03-04 1984-09-11 株式会社　バイオ・エンジニアリング・ラボラトリ−ズ 癒着阻止性医用材料およびその製造法
DE3474511D1 (en) * 1983-11-01 1988-11-17 Terumo Corp Pharmaceutical composition containing urokinase
EP0174835A1 (en) * 1984-09-11 1986-03-19 The Upjohn Company Human tissue plasminogen activator and recombinant DNA compounds
NZ217844A (en) * 1985-10-11 1989-10-27 Sumitomo Pharma A sustained release pharmaceutical composition containing silicone elastomer and an albumin

Also Published As

Publication number Publication date
DE3682754D1 (de) 1992-01-16
AU586306B2 (en) 1989-07-06
AU6656686A (en) 1987-06-18
ZA869434B (en) 1988-07-27
EP0227400B1 (en) 1991-12-04
CA1297791C (en) 1992-03-24
KR870005646A (ko) 1987-07-06
JPH0764749B2 (ja) 1995-07-12
JPS62187414A (ja) 1987-08-15
EP0227400A2 (en) 1987-07-01
EP0227400A3 (en) 1988-09-14

Similar Documents

Publication Publication Date Title
ZA868964B (en) Method for inhibiting post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug
AU590308B2 (en) Rate controlled dispenser for administering beneficial agent
GB8514445D0 (en) Transdermal administration of fentanyl
AU566460B2 (en) Intermediates in the synthesis of acyltripeptide immunostimulants
AU564989B2 (en) Location of starting site of ventricular arrhythmias
EP0364561A4 (en) Factor vii/viia active site inhibitors
GB8418424D0 (en) Inhibition of platelets aggregation
AU6110286A (en) Poly-kringle plasminogen activator
AU5730286A (en) Treatment of factor viii inhibitors
EP0225162A3 (en) Inhibition of post-surgical adhesion formation by the topical administration of non-steroidal anti-inflammatory drug
GR3003305T3 (en) Inhibition of post-surgical adhesion formation by the topical administration of tissue plasminogen activator
AU568920B2 (en) Pharmaceutical compositions of 3,4-dihydroisoquinolinium salts
GB8626119D0 (en) Construction of structures
AU4387885A (en) Self-adhesive plaster for transdermal administration
AU6180486A (en) Novel tissue plasminogen activator derivatives
AU589852B2 (en) Nitrate-containing plaster
CA1271748C (en) BENZAZEPINE DERIVATIVES
ZA854947B (en) Beta-lactam derivatives as anti-inflammatory and anti-degenerative agents
AU576160B2 (en) Incorporation of mercaptobenzothiazoles
GB8620649D0 (en) Discharge of defrost water
AU562238B2 (en) Telescopically extended masonry tie
AU578719B2 (en) Patch dressing for the administration of controlled amounts of ointment
ZA865362B (en) The use of tnf for the preparation of medicaments
AU590003B2 (en) Masonry anchor
AU3992685A (en) Preperation of amidinoureas