GR3021313T3 - N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders. - Google Patents

N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders.

Info

Publication number: GR3021313T3
Authority: GR; Greece
Prior art keywords: gastrin; cholecystokinin; drugs; prevention; treatment
Prior art date: 1993-01-07

Application number

GR960401619T

Other languages

English (en)

Inventor

Marc Capet

Marie-Christine Dubroeucq

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-01-07

Filing date

1996-10-10

Publication date

1997-01-31

1996-10-10 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1997-01-31 Publication of GR3021313T3 publication Critical patent/GR3021313T3/el

Links

102100021022 Gastrin Human genes 0.000 title abstract 2
108010052343 Gastrins Proteins 0.000 title abstract 2
AOXOCDRNSPFDPE-UKEONUMOSA-N chembl413654 Chemical compound C([C@H](C(=O)NCC(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C1=CC=C(O)C=C1 AOXOCDRNSPFDPE-UKEONUMOSA-N 0.000 title abstract 2
238000011282 treatment Methods 0.000 title abstract 2
102100025841 Cholecystokinin Human genes 0.000 title 1
101800001982 Cholecystokinin Proteins 0.000 title 1
229940107137 cholecystokinin Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
230000002265 prevention Effects 0.000 title 1
IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Ophthalmology & Optometry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Peptides Or Proteins (AREA)

GR960401619T 1993-01-07 1996-10-10 N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders. GR3021313T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9300077A FR2700165B1 (fr)	1993-01-07	1993-01-07	Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.
PCT/FR1994/000008 WO1994015914A1 (fr)	1993-01-07	1994-01-03	N-acyl pyrrolidines et des medicaments pour le traitement ou la prevention des desordres lies a la ckk et la gastrine

Publications (1)

Publication Number	Publication Date
GR3021313T3 true GR3021313T3 (en)	1997-01-31

Family

ID=9442866

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR960401619T GR3021313T3 (en)	1993-01-07	1996-10-10	N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders.

Country Status (19)

Country	Link
US (1)	US5624939A (el)
EP (1)	EP0678088B1 (el)
JP (1)	JPH08505614A (el)
KR (1)	KR960700228A (el)
AT (1)	ATE143946T1 (el)
AU (1)	AU5819294A (el)
CA (1)	CA2152281A1 (el)
DE (1)	DE69400702T2 (el)
DK (1)	DK0678088T3 (el)
ES (1)	ES2094048T3 (el)
FR (1)	FR2700165B1 (el)
GR (1)	GR3021313T3 (el)
HU (1)	HUT74095A (el)
IL (1)	IL108290A0 (el)
NO (1)	NO952559L (el)
NZ (1)	NZ259398A (el)
RU (1)	RU95116448A (el)
WO (1)	WO1994015914A1 (el)
ZA (1)	ZA9480B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2721608B1 (fr) *	1994-06-22	1996-07-19	Rhone Poulenc Rorer Sa	Dérivés de thiazolidine, leur préparation et les médicaments les contenant.
FR2744361B1 (fr) *	1996-02-07	1998-02-27	Rhone Poulenc Rorer Sa	Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
FR2744362B1 (fr) *	1996-02-07	1998-02-27	Rhone Poulenc Rorer Sa	Application de derives de pyrrolidine a la preparation de medicaments destines au traitement de l'abus de drogues ou de substances donnant lieu a des pharmacomanies ou a un usage excessif
TW442449B (en)	1996-07-04	2001-06-23	Hoechst Ag	Process for preparing 1,2-dichloroethane by direct chlorination
US6737409B2 (en) *	2001-07-19	2004-05-18	Hoffmann-La Roche Inc.	Dolastatin 10 derivatives
DE10218377B4 (de) *	2002-04-25	2004-03-11	Rea Gesellschaft Für Recycling Von Energie Und Abfall Mbh	Verfahren und Vorrichtung zur Schwerstoffabtrennung aus Aufschlämmungen
US8247438B2 (en)	2008-02-27	2012-08-21	Neuropill, Inc.	Methods for treating schizophrenia

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0124317B1 (en) *	1983-04-27	1990-04-11	Ici Americas Inc.	Proline derivatives
FR2667864B2 (fr) *	1990-03-07	1994-08-05	Rhone Poulenc Sante	Derives de n-phenyl glycinamides, leur preparation et les medicaments les contenant.
FR2678938B1 (fr) *	1991-07-10	1993-10-08	Rhone Poulenc Rorer Sa	Derives de pyrrolidine, leur preparation et les medicaments les contenant.

1993
- 1993-01-07 FR FR9300077A patent/FR2700165B1/fr not_active Expired - Fee Related
1994
- 1994-01-03 KR KR1019950702823A patent/KR960700228A/ko not_active Withdrawn
- 1994-01-03 DE DE69400702T patent/DE69400702T2/de not_active Expired - Fee Related
- 1994-01-03 CA CA002152281A patent/CA2152281A1/fr not_active Abandoned
- 1994-01-03 NZ NZ259398A patent/NZ259398A/en unknown
- 1994-01-03 ES ES94903939T patent/ES2094048T3/es not_active Expired - Lifetime
- 1994-01-03 HU HU9502067A patent/HUT74095A/hu unknown
- 1994-01-03 JP JP6515747A patent/JPH08505614A/ja active Pending
- 1994-01-03 AT AT94903939T patent/ATE143946T1/de not_active IP Right Cessation
- 1994-01-03 US US08/448,406 patent/US5624939A/en not_active Expired - Fee Related
- 1994-01-03 RU RU95116448/04A patent/RU95116448A/ru unknown
- 1994-01-03 WO PCT/FR1994/000008 patent/WO1994015914A1/fr not_active Ceased
- 1994-01-03 AU AU58192/94A patent/AU5819294A/en not_active Abandoned
- 1994-01-03 EP EP94903939A patent/EP0678088B1/fr not_active Expired - Lifetime
- 1994-01-03 DK DK94903939.0T patent/DK0678088T3/da active
- 1994-01-06 ZA ZA9480A patent/ZA9480B/xx unknown
- 1994-01-06 IL IL10829094A patent/IL108290A0/xx unknown
1995
- 1995-06-26 NO NO952559A patent/NO952559L/no unknown
1996
- 1996-10-10 GR GR960401619T patent/GR3021313T3/el unknown

Also Published As

Publication number	Publication date
NO952559D0 (no)	1995-06-26
CA2152281A1 (fr)	1994-07-21
EP0678088A1 (fr)	1995-10-25
ES2094048T3 (es)	1997-01-01
JPH08505614A (ja)	1996-06-18
AU5819294A (en)	1994-08-15
NZ259398A (en)	1996-02-27
ZA9480B (en)	1994-08-11
FR2700165A1 (fr)	1994-07-08
DE69400702D1 (de)	1996-11-14
WO1994015914A1 (fr)	1994-07-21
HUT74095A (en)	1996-11-28
RU95116448A (ru)	1997-06-10
US5624939A (en)	1997-04-29
ATE143946T1 (de)	1996-10-15
DE69400702T2 (de)	1997-03-06
EP0678088B1 (fr)	1996-10-09
KR960700228A (ko)	1996-01-19
NO952559L (no)	1995-06-26
DK0678088T3 (da)	1996-11-18
FR2700165B1 (fr)	1995-02-17
IL108290A0 (en)	1994-04-12
HU9502067D0 (en)	1995-09-28

Publication	Publication Date	Title
HU9503986D0 (en)	1996-03-28	Perhydroisoindole derivatives as p substance antagonists
DE59409312D1 (de)	2000-05-31	Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten
AU2672995A (en)	1995-12-21	{a}-annelated pyrrole derivatives and pharmaceutical uses thereof
AU685176B2 (en)	1998-01-15	Alkoxy alkyl carbamates from imidazo (1,2-a)pyridines
IL110349A0 (en)	1994-10-21	Tetrahydro-1h- benzazepinones containing acid surrogates
DE69511544D1 (de)	1999-09-23	Amidderivate und ihre therapeutische verwendung
GR3021313T3 (en)	1997-01-31	N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders.
NO172640C (no)	1993-08-18	Analogifremgangsmaate ved fremstilling av terapeutisk aktive piperazinderivater
HU9502068D0 (en)	1995-09-28	N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders
TW259787B (el)	1995-10-11
NZ320522A (en)	1999-03-29	Piperazinylalkylthiopyrimidine derivatives, pharmaceutical compositions containing the same and a process for the preparation of the compounds
GR3025050T3 (en)	1998-01-30	Etoposide derivatives, process for their preparation, their use as a drug and in the preparation of a drug for treating cancer.
AU2796695A (en)	1996-01-15	Pyrrolidine derivatives for the treatment of cholecystokinine and gastrine-related disorders