GR3025502T3 - Drugs, their manufacture, and their use as painkillers and/or to treat inflammations in humans and animals. - Google Patents

Drugs, their manufacture, and their use as painkillers and/or to treat inflammations in humans and animals.

Info

Publication number
GR3025502T3
GR3025502T3 GR970403151T GR970403151T GR3025502T3 GR 3025502 T3 GR3025502 T3 GR 3025502T3 GR 970403151 T GR970403151 T GR 970403151T GR 970403151 T GR970403151 T GR 970403151T GR 3025502 T3 GR3025502 T3 GR 3025502T3
Authority
GR
Greece
Prior art keywords
painkillers
humans
drugs
animals
manufacture
Prior art date
Application number
GR970403151T
Other languages
English (en)
Inventor
Gerd Geisslinger
Kay Brune
Original Assignee
Paz Arzneimittelentwicklung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6414093&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3025502(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Paz Arzneimittelentwicklung filed Critical Paz Arzneimittelentwicklung
Publication of GR3025502T3 publication Critical patent/GR3025502T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR970403151T 1990-09-12 1997-11-26 Drugs, their manufacture, and their use as painkillers and/or to treat inflammations in humans and animals. GR3025502T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4028906A DE4028906A1 (de) 1990-09-12 1990-09-12 Arzneimittel sowie deren herstellung und deren verwendung bei der bekaempfung von schmerzen und/oder entzuendungen und/oder fieber an tieren und menschen
PCT/EP1991/001568 WO1992004018A1 (de) 1990-09-12 1991-08-19 Arzneimittel sowie deren herstellung und deren verwendung bei der bekämpfung von schmerzen und/oder entzündungen an tieren und menschen

Publications (1)

Publication Number Publication Date
GR3025502T3 true GR3025502T3 (en) 1998-02-27

Family

ID=6414093

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970403151T GR3025502T3 (en) 1990-09-12 1997-11-26 Drugs, their manufacture, and their use as painkillers and/or to treat inflammations in humans and animals.

Country Status (14)

Country Link
US (2) US5200198A (el)
EP (1) EP0607128B2 (el)
JP (1) JP3305315B2 (el)
AT (1) ATE158182T1 (el)
AU (1) AU654498B2 (el)
CA (1) CA2087723C (el)
DE (2) DE4028906A1 (el)
DK (1) DK0607128T4 (el)
ES (1) ES2106785T5 (el)
FI (1) FI103180B1 (el)
GR (1) GR3025502T3 (el)
HU (1) HU225887B1 (el)
RU (1) RU2080116C1 (el)
WO (1) WO1992004018A1 (el)

Families Citing this family (53)

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DE4140172C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Ibuprofen enthaltendes Arzneimittel
DE4140184C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Akutform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140183C2 (de) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retardform für ein Flurbiprofen enthaltendes Arzneimittel
DE4140185C2 (de) * 1991-12-05 1996-02-01 Alfatec Pharma Gmbh Ein 2-Arylpropionsäurederivat in Nanosolform enthaltendes Arzneimittel und seine Herstellung
DE4216756C2 (de) * 1992-05-21 1994-08-25 Pharmatrans Sanaq Ag 2-Arylpropionsäure-Zubereitungen und Verfahren zu ihrer Herstellung
AU672269B2 (en) * 1992-12-02 1996-09-26 Aesica Pharmaceuticals Ltd Process for preparing substantially pure enantiomers of phenylpropionic acids
DE4319438C1 (de) * 1993-06-11 1994-06-01 Gerd Dr Dr Geislinger Arzneimittel auf der Grundlage von Ketoprofen zur Bekämpfung von Schmerzen und/oder Entzündungen und/oder Fieber an Menschen und Tieren
JP3782834B2 (ja) * 1994-10-26 2006-06-07 株式会社トクホン 鎮痛抗炎症貼付剤
IT1271800B (it) * 1994-12-27 1997-06-09 Zambon Spa Processo di preparazione degli enantiomeri dell'acido 2- (2-fluoro- 4-bifenil) propionico
US6160018A (en) * 1995-03-13 2000-12-12 Loma Linda University Medical Center Prophylactic composition and method for alzheimer's Disease
US5955504A (en) * 1995-03-13 1999-09-21 Loma Linda University Medical Center Colorectal chemoprotective composition and method of preventing colorectal cancer
US5981592A (en) * 1995-03-13 1999-11-09 Loma Linda University Medical Center Method and composition for treating cystic fibrosis
AT408067B (de) * 1995-03-17 2001-08-27 Gebro Pharma Gmbh Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung
GB9523833D0 (en) * 1995-11-22 1996-01-24 Boots Co Plc Medical treatment
US5702720A (en) * 1995-12-22 1997-12-30 Minnesota Mining And Manufacturing Company Transdermal device for the delivery of flurbiprofen
EP1642575B1 (en) * 1997-03-10 2009-10-28 Loma Linda University Medical Center Use of r-carprofen for the prevention of alzheimer's disease
GB9705989D0 (en) * 1997-03-22 1997-05-07 Boots Co Plc Therapeutic composition
SE9704400D0 (sv) * 1997-11-28 1997-11-28 Astra Ab Porous inorganic particles as carriers for drug substances
ATE353010T1 (de) 1998-09-03 2007-02-15 Univ Loma Linda Med Pharmazeutische zusammensetzung und verwendung von rnsaid zur behandlung der entzündung
AU2004222809B2 (en) * 1998-09-03 2007-06-28 Loma Linda University Medical Center Pharmaceutical Composition and Method for Treatment of Inflammation
DE19907895A1 (de) * 1999-02-24 2000-11-16 Paz Arzneimittelentwicklung Verwendung von R-Arylpropionsäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen bei Mensch und Tier, welche durch die Hemmung der Aktivierung von NF-kB therapeutisch beeinflußt werden können
AU5702201A (en) * 2000-04-13 2001-10-30 Mayo Foundation Abeta<sub>42</sub> lowering agents
US20060004086A1 (en) * 2000-04-13 2006-01-05 Mayo Foundation For Medical Education And Research Method of reducing Abeta42 and treating diseases
US20080021085A1 (en) * 2000-04-13 2008-01-24 Mayo Foundation For Medical Education And Research Method of reducing abeta42 and treating diseases
DE10047319A1 (de) * 2000-09-25 2002-04-18 Paz Arzneimittelentwicklung Verwendung von R-Arylpropionsäuren zur Herstellung von Arzneimitteln zur Behandlung von Erkrankungen, welche durch die Hemmung der Aktivierung des nukleären Transkriptionsfaktors AP-1 therapeutisch beeinflußt werden können
US6497901B1 (en) * 2000-11-02 2002-12-24 Royer Biomedical, Inc. Resorbable matrices for delivery of bioactive compounds
DE60213230T2 (de) 2001-05-21 2006-11-23 Alcon Inc. Verwendung von NF-Kappa.B Inhibitoren zur Behandlung von Augentrockenheit
US20030027867A1 (en) * 2001-06-29 2003-02-06 Myriad Genetics, Incorporated Use of R-NSAID compounds for anti-HIV treatment
US20030143165A1 (en) * 2002-01-25 2003-07-31 Allan Evans NSAID-containing topical formulations that demonstrate chemopreventive activity
US7247328B2 (en) * 2002-05-31 2007-07-24 Zinpro Corporation Chromium (III) alpha amino acid complexes
US7129375B2 (en) 2002-10-16 2006-10-31 Zinpro Corporation Metal complexes of α amino dicarboxylic acids
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
US6953507B2 (en) * 2003-03-21 2005-10-11 Ecolab Inc. Low temperature cleaning
KR20060040676A (ko) * 2003-07-11 2006-05-10 미리어드 제네틱스, 인크. 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형
US20050171207A1 (en) * 2003-09-26 2005-08-04 Myriad Genetics, Incorporated Method and composition for combination treatment of neurodegenerative disorders
FR2865648B1 (fr) * 2004-02-03 2006-06-30 Philippe Perovitch Procede de diffusion de molecules insolubles en milieu aqueux et composition mettant en oeuvre ce procede
WO2006001877A2 (en) * 2004-04-13 2006-01-05 Myriad Genetics, Inc. Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
AU2005241023A1 (en) * 2004-04-29 2005-11-17 Keystone Retaining Wall Systems, Inc. Veneers for walls, retaining walls and the like
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
KR20080039876A (ko) * 2005-07-22 2008-05-07 미리어드 제네틱스, 인크. 높은 약물 충진 제형 및 투여형
US20070042094A1 (en) 2005-08-22 2007-02-22 Alcide Corporation Oxidation method and compositions therefor
EP2046119A2 (en) * 2006-07-07 2009-04-15 Myriad Genetics, Inc. Treatment of psychiatric disorders
MX2010006608A (es) * 2007-12-21 2010-10-05 Paz Arzneimittelentwicklung Composiciones farmaceuticas y produccion y uso de las mismas en el tratamiento de neuropatias asociadas con el dolor.
US20090162421A1 (en) * 2007-12-21 2009-06-25 Paz Arzneimittel-Entwicklungsgesellschaft Mbh Drugs as well as their production and use in the treatment of pain-associated neuropathies
SI2387391T1 (sl) * 2009-07-24 2017-04-26 Mika Pharma Gesellschaft Fuer Die Entwicklung Und Vermarktung Pharmazeutischer Produkte Mbh Postopek za pripravo tekočega sestavka, ki se nanaša na kožo v obliki pene, in sestavka, ki se lahko nanaša topično
EP2468270A1 (en) 2010-12-21 2012-06-27 GALENpharma GmbH (R)-2-(3-fluoro-4-phenylphenyl)propionic acid for use in the treatment of skin diseases
US20150183737A1 (en) * 2012-07-20 2015-07-02 Vanderbilt University Compositions and methods for substrate-selective inhibition of endocannabinoid oxygenation
US9578879B1 (en) 2014-02-07 2017-02-28 Gojo Industries, Inc. Compositions and methods having improved efficacy against spores and other organisms
CN113262216A (zh) * 2020-02-14 2021-08-17 北京泰德制药股份有限公司 一种用于消除皮表红肿镇痛的外用制剂
CN118125916A (zh) * 2022-09-23 2024-06-04 南京知和医药科技有限公司 一种s-（+）-氟比洛芬盐及其制备方法、药物组合物和用途
CN119837880B (zh) * 2024-12-18 2025-08-29 中南大学 一种含氟比洛芬的药物组合物及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3784705A (en) * 1964-01-24 1974-01-08 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
US4209638A (en) * 1977-03-08 1980-06-24 The Boots Company Limited Preparation of therapeutic agents
GR64816B (en) * 1977-03-08 1980-06-03 Boots Co Ltd Resolution of flurbiprofen ii/iii
ZA828453B (en) † 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
JPS6283885A (ja) † 1985-10-08 1987-04-17 Nitto Electric Ind Co Ltd 酵素固定膜及びその製造方法
US4927854A (en) * 1987-12-24 1990-05-22 Analgesic Associates Sustained/enhanced analgesia
WO1991006295A1 (en) † 1989-11-06 1991-05-16 Sepracor, Inc. Analgesic composition containing optically pure s(+) flurbiprofen

Also Published As

Publication number Publication date
FI931097A0 (fi) 1993-03-11
DE4028906C2 (el) 1992-10-29
DE59108854D1 (de) 1997-10-23
FI103180B (fi) 1999-05-14
EP0607128B1 (de) 1997-09-17
AU8335291A (en) 1992-03-30
DK0607128T4 (da) 2007-05-07
EP0607128A1 (de) 1994-07-27
ATE158182T1 (de) 1997-10-15
HUT63564A (en) 1993-09-28
HU9300636D0 (en) 1993-05-28
CA2087723C (en) 2002-07-23
DE4028906A1 (de) 1992-03-19
EP0607128B2 (de) 2007-02-21
HU225887B1 (en) 2007-11-28
WO1992004018A1 (de) 1992-03-19
ES2106785T3 (es) 1997-11-16
DK0607128T3 (da) 1998-04-14
AU654498B2 (en) 1994-11-10
ES2106785T5 (es) 2007-10-16
US5206029A (en) 1993-04-27
CA2087723A1 (en) 1992-03-13
US5200198A (en) 1993-04-06
FI103180B1 (fi) 1999-05-14
JPH06500313A (ja) 1994-01-13
RU2080116C1 (ru) 1997-05-27
FI931097L (fi) 1993-03-11
JP3305315B2 (ja) 2002-07-22

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