GR3026094T3 - Orally administerable esters of 14 alpha,15 alpha-methylene-oestradiol with an oestrogenic action - Google Patents
Orally administerable esters of 14 alpha,15 alpha-methylene-oestradiol with an oestrogenic actionInfo
- Publication number
- GR3026094T3 GR3026094T3 GR980400262T GR980400262T GR3026094T3 GR 3026094 T3 GR3026094 T3 GR 3026094T3 GR 980400262 T GR980400262 T GR 980400262T GR 980400262 T GR980400262 T GR 980400262T GR 3026094 T3 GR3026094 T3 GR 3026094T3
- Authority
- GR
- Greece
- Prior art keywords
- alpha
- esters
- oestradiol
- methylene
- orally administerable
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 230000001076 estrogenic effect Effects 0.000 title abstract 2
- 239000003433 contraceptive agent Substances 0.000 abstract 2
- 229940124558 contraceptive agent Drugs 0.000 abstract 2
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000262 estrogen Substances 0.000 abstract 1
- 229960002568 ethinylestradiol Drugs 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4322186A DE4322186A1 (de) | 1993-07-03 | 1993-07-03 | Oral estrogen wirksame Ester des 14alpha, 15alpha-Methylen-estradiols |
| PCT/DE1994/000662 WO1995001988A1 (de) | 1993-07-03 | 1994-06-15 | ORAL ESTROGEN WIRKSAME ESTER DES 14α,15α-METHYLEN-ESTRADIOLS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3026094T3 true GR3026094T3 (en) | 1998-05-29 |
Family
ID=6491888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR980400262T GR3026094T3 (en) | 1993-07-03 | 1998-02-11 | Orally administerable esters of 14 alpha,15 alpha-methylene-oestradiol with an oestrogenic action |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0707593B1 (el) |
| CN (1) | CN1102830A (el) |
| AT (1) | ATE161542T1 (el) |
| AU (1) | AU6923494A (el) |
| DE (3) | DE4322186A1 (el) |
| ES (1) | ES2113106T3 (el) |
| GR (1) | GR3026094T3 (el) |
| WO (1) | WO1995001988A1 (el) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19906159A1 (de) * | 1999-02-09 | 2000-08-10 | Schering Ag | 16-Hydroxyestratriene als selektiv wirksame Estrogene |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA745995A (en) * | 1962-08-17 | 1966-11-08 | Paturet Michel | 3 ou 17-hexahydrobenzyloxycarbonates de composes steroides et procede |
| DD145919B1 (de) * | 1978-06-28 | 1982-06-30 | Kurt Ponsold | Verfahren zur herstellung von 14,1 -methylenderivaten der oestranreihe |
| FR2531089B1 (fr) * | 1982-07-27 | 1986-03-21 | Pharmascience Lab | Nouveaux derives oestraniques destines a des applications pharmacologiques par voie topique, et leur procede de preparation |
| DE4239946C2 (de) * | 1992-11-27 | 2001-09-13 | Jenapharm Gmbh | Estranderivate mit einer 14alpha,15alpha-Methylengruppe und Verfahren zu ihrer Herstellung |
-
1993
- 1993-07-03 DE DE4322186A patent/DE4322186A1/de not_active Withdrawn
-
1994
- 1994-06-15 AU AU69234/94A patent/AU6923494A/en not_active Abandoned
- 1994-06-15 EP EP94917548A patent/EP0707593B1/de not_active Expired - Lifetime
- 1994-06-15 WO PCT/DE1994/000662 patent/WO1995001988A1/de not_active Ceased
- 1994-06-15 DE DE59404903T patent/DE59404903D1/de not_active Expired - Lifetime
- 1994-06-15 ES ES94917548T patent/ES2113106T3/es not_active Expired - Lifetime
- 1994-06-15 DE DE4494826T patent/DE4494826D2/de not_active Expired - Lifetime
- 1994-06-15 AT AT94917548T patent/ATE161542T1/de not_active IP Right Cessation
- 1994-07-02 CN CN94108120A patent/CN1102830A/zh active Pending
-
1998
- 1998-02-11 GR GR980400262T patent/GR3026094T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6923494A (en) | 1995-02-06 |
| DE4494826D2 (de) | 1997-07-24 |
| DE59404903D1 (de) | 1998-02-05 |
| WO1995001988A1 (de) | 1995-01-19 |
| CN1102830A (zh) | 1995-05-24 |
| EP0707593A1 (de) | 1996-04-24 |
| EP0707593B1 (de) | 1997-12-29 |
| ATE161542T1 (de) | 1998-01-15 |
| ES2113106T3 (es) | 1998-04-16 |
| DE4322186A1 (de) | 1995-01-12 |
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