GR3029471T3 - 2-substituted quinolines for treating leishmanioses. - Google Patents
2-substituted quinolines for treating leishmanioses.Info
- Publication number
- GR3029471T3 GR3029471T3 GR990400568T GR990400568T GR3029471T3 GR 3029471 T3 GR3029471 T3 GR 3029471T3 GR 990400568 T GR990400568 T GR 990400568T GR 990400568 T GR990400568 T GR 990400568T GR 3029471 T3 GR3029471 T3 GR 3029471T3
- Authority
- GR
- Greece
- Prior art keywords
- group
- alkyl
- alkenyl
- phenyl
- pct
- Prior art date
Links
- -1 2-substituted quinolines Chemical class 0.000 title abstract 4
- 125000003342 alkenyl group Chemical group 0.000 abstract 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000003368 amide group Chemical group 0.000 abstract 2
- 125000005805 dimethoxy phenyl group Chemical group 0.000 abstract 2
- 125000006701 (C1-C7) alkyl group Chemical group 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical group C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
- 125000005741 alkyl alkenyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 229940111121 antirheumatic drug quinolines Drugs 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003248 quinolines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9112174A FR2682107B1 (fr) | 1991-10-03 | 1991-10-03 | Quinoleines 2-substituees pour le traitement des leishmanioses. |
| PCT/FR1992/000903 WO1993007125A1 (fr) | 1991-10-03 | 1992-09-29 | Quinoleines 2-substituees pour le traitement des leishmanioses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3029471T3 true GR3029471T3 (en) | 1999-05-28 |
Family
ID=9417546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR990400568T GR3029471T3 (en) | 1991-10-03 | 1999-02-24 | 2-substituted quinolines for treating leishmanioses. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5541196A (el) |
| EP (1) | EP0606380B1 (el) |
| JP (1) | JP3728627B2 (el) |
| AT (1) | ATE173727T1 (el) |
| DE (1) | DE69227695D1 (el) |
| ES (1) | ES2127762T3 (el) |
| FR (1) | FR2682107B1 (el) |
| GR (1) | GR3029471T3 (el) |
| OA (1) | OA09930A (el) |
| WO (1) | WO1993007125A1 (el) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2819507B1 (fr) * | 2001-01-17 | 2007-09-28 | Inst Rech Developpement Ird | Quinoleines substituees pour le traitement de co-infections a protozoaires et a retrovirus |
| US20040241168A1 (en) * | 2001-03-16 | 2004-12-02 | O'daly Jose A. | Compositions and methods for the treatment and clinical remission of psoriasis |
| US6673351B1 (en) | 2001-03-16 | 2004-01-06 | Astralis, Llc | Compositions and methods for the treatment and clinical remission of psoriasis |
| US9321730B2 (en) * | 2007-08-21 | 2016-04-26 | The Hong Kong Polytechnic University | Method of making and administering quinoline derivatives as anti-cancer agents |
| FR2929943B1 (fr) | 2008-04-15 | 2010-09-24 | Inst Rech Developpement Ird | Sels de quinoleines 2-substituees |
| FR2931479B1 (fr) * | 2008-05-20 | 2012-12-07 | I R D | Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation |
| WO2012083866A1 (en) | 2010-12-22 | 2012-06-28 | The Hong Kong Polytechnic University | Quinoline derivatives as anti-cancer agents |
| MX2016004464A (es) * | 2013-10-10 | 2017-01-12 | Univ Leuven Kath | Derivados novedosos de pradimicina para el tratamiento de enfermedades provocadas por kinetoplastidos. |
| ES2818531T3 (es) | 2015-12-17 | 2021-04-13 | Biokine Therapeutics Ltd | Moléculas pequeñas para inhibir la actividad de las quimiocinas y/o el crecimiento de células cancerosas |
| WO2020206252A1 (en) * | 2019-04-03 | 2020-10-08 | University Of Central Florida Research Foundation, Inc. | Antimalarial compounds |
| CN114096524B (zh) | 2019-05-15 | 2025-03-04 | 阿龙拜欧有限公司 | 用于治疗癌症、抑制趋化因子活性和/或诱导细胞死亡的小分子 |
| CN110229101B (zh) * | 2019-05-31 | 2020-11-03 | 浙江工业大学 | 用于检测黏度的aie荧光化合物及其制备与应用 |
| WO2021150645A1 (en) * | 2020-01-20 | 2021-07-29 | Crescenta Biosciences | Novel cell metabolism modulating compounds and uses thereof |
| EP4171736A4 (en) | 2020-06-27 | 2024-07-03 | Crescenta Biosciences | NEW CELL METABOLISM MODULATING COMPOUNDS AND THEIR USES |
| US12138243B2 (en) | 2021-12-31 | 2024-11-12 | Crescenta Biosciences | Antiviral use of FABP4 modulating compounds |
| WO2025091990A1 (zh) * | 2023-10-30 | 2025-05-08 | 湖北工程学院 | 一种壳聚糖铜MOF材料及其应用、β-硼亚胺化合物和羟基化合物的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3636216A (en) * | 1968-09-26 | 1972-01-18 | Salsbury Lab | Coccidiosis control with quinalinol derivatives |
| US4209519A (en) * | 1978-03-13 | 1980-06-24 | The United States Of America As Represented By The Secretary Of The Army | Anti-leishmanial lepidine derivatives |
| IL89026A (en) * | 1988-01-29 | 1993-02-21 | Lilly Co Eli | Substituted quinolines and cinnolines, process for their preparation and fungicidal, insecticidal and miticidal compositions containing them |
-
1991
- 1991-10-03 FR FR9112174A patent/FR2682107B1/fr not_active Expired - Lifetime
-
1992
- 1992-09-29 WO PCT/FR1992/000903 patent/WO1993007125A1/fr not_active Ceased
- 1992-09-29 JP JP50665193A patent/JP3728627B2/ja not_active Expired - Lifetime
- 1992-09-29 EP EP92921565A patent/EP0606380B1/fr not_active Expired - Lifetime
- 1992-09-29 US US08/211,239 patent/US5541196A/en not_active Expired - Lifetime
- 1992-09-29 AT AT92921565T patent/ATE173727T1/de not_active IP Right Cessation
- 1992-09-29 ES ES92921565T patent/ES2127762T3/es not_active Expired - Lifetime
- 1992-09-29 DE DE69227695T patent/DE69227695D1/de not_active Expired - Lifetime
-
1994
- 1994-03-30 OA OA60489A patent/OA09930A/fr unknown
-
1999
- 1999-02-24 GR GR990400568T patent/GR3029471T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2127762T3 (es) | 1999-05-01 |
| FR2682107A1 (fr) | 1993-04-09 |
| OA09930A (fr) | 1994-11-15 |
| FR2682107B1 (fr) | 1995-04-21 |
| JPH07501048A (ja) | 1995-02-02 |
| DE69227695D1 (de) | 1999-01-07 |
| EP0606380B1 (fr) | 1998-11-25 |
| US5541196A (en) | 1996-07-30 |
| JP3728627B2 (ja) | 2005-12-21 |
| ATE173727T1 (de) | 1998-12-15 |
| WO1993007125A1 (fr) | 1993-04-15 |
| EP0606380A1 (fr) | 1994-07-20 |
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