GR3032171T3 - Spiroheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them - Google Patents

Spiroheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them

Info

Publication number: GR3032171T3
Authority: GR; Greece
Prior art keywords: alkyl; substd; opt; alkoxy; halo
Prior art date: 1995-05-17

Application number

GR990403257T

Other languages

English (en)

Inventor

Claude Guillonneau

Yves Charton

Gilbert Regnier

Emmanuel Canet

Michel Lonchampt

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-17

Filing date

1999-12-17

Publication date

2000-04-27

1999-12-17 Application filed by Adir filed Critical Adir

2000-04-27 Publication of GR3032171T3 publication Critical patent/GR3032171T3/el

Links

150000001875 compounds Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 6
125000003545 alkoxy group Chemical group 0.000 abstract 4
125000005843 halogen group Chemical group 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 2
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
125000002950 monocyclic group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
125000000278 alkyl amino alkyl group Chemical group 0.000 abstract 1
125000004103 aminoalkyl group Chemical group 0.000 abstract 1
125000002618 bicyclic heterocycle group Chemical group 0.000 abstract 1
125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

GR990403257T 1995-05-17 1999-12-17 Spiroheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them GR3032171T3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9505833A FR2734265B1 (fr)	1995-05-17	1995-05-17	Nouveaux composes spiro heterocycliques, leur procede de preparation et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number	Publication Date
GR3032171T3 true GR3032171T3 (en)	2000-04-27

Family

ID=9479065

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR990403257T GR3032171T3 (en)	1995-05-17	1999-12-17	Spiroheterocyclic compounds, process for their preparation and pharmaceutical compositions containing them

Country Status (15)

Country	Link
US (1)	US5698567A (el)
EP (1)	EP0743312B1 (el)
JP (1)	JPH08311067A (el)
CN (1)	CN1058014C (el)
AT (1)	ATE186729T1 (el)
AU (1)	AU702587B2 (el)
CA (1)	CA2176668C (el)
DE (1)	DE69605145T2 (el)
DK (1)	DK0743312T3 (el)
ES (1)	ES2142030T3 (el)
FR (1)	FR2734265B1 (el)
GR (1)	GR3032171T3 (el)
NO (1)	NO307756B1 (el)
NZ (1)	NZ286604A (el)
ZA (1)	ZA963950B (el)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6262066B1 (en)	1998-07-27	2001-07-17	Schering Corporation	High affinity ligands for nociceptin receptor ORL-1
ID29137A (id) *	1998-07-27	2001-08-02	Schering Corp	Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
AU2003236366A1 (en) *	2002-04-05	2003-10-20	Sankyo Company, Limited	Oxazolidinone derivatives
US7205006B2 (en) *	2003-09-25	2007-04-17	Prime Pharmaceutical Corporation	Mahonia aquifolium extract, extraction process and pharmaceutical composition containing the same
JPWO2005047286A1 (ja) *	2003-11-13	2007-05-31	小野薬品工業株式会社	スピロ複素環化合物
US8071624B2 (en)	2004-06-24	2011-12-06	Incyte Corporation	N-substituted piperidines and their use as pharmaceuticals
CA2571258A1 (en) *	2004-06-24	2006-01-05	Incyte Corporation	Amido compounds and their use as pharmaceuticals
CA2584502A1 (en)	2004-06-24	2006-01-05	Incyte Corporation	2-methylpropanamides and their use as pharmaceuticals
US8110581B2 (en)	2004-11-10	2012-02-07	Incyte Corporation	Lactam compounds and their use as pharmaceuticals
ES2547724T3 (es) *	2004-11-10	2015-10-08	Incyte Corporation	Compuestos de lactama y su uso como productos farmacéuticos
WO2007028638A1 (en)	2005-09-09	2007-03-15	Euro-Celtique S.A.	Fused and spirocycle compounds and the use thereof
CL2008001839A1 (es)	2007-06-21	2009-01-16	Incyte Holdings Corp	Compuestos derivados de 2,7-diazaespirociclos, inhibidores de 11-beta hidroxil esteroide deshidrogenasa tipo 1; composicion farmaceutica que comprende a dichos compuestos; utiles para tratar la obesidad, diabetes, intolerancia a la glucosa, diabetes tipo ii, entre otras enfermedades.
GB201416351D0 (en)	2014-09-16	2014-10-29	Shire Internat Gmbh	Heterocyclic derivatives
GB201416352D0 (en)	2014-09-16	2014-10-29	Shire Internat Gmbh	Spirocyclic derivatives
GB201416346D0 (en) *	2014-09-16	2014-10-29	Shire Internat Gmbh	Spirocyclic derivatives
SI3402784T1 (sl)	2016-01-13	2020-07-31	Gruenenthal Gmbh	Derivati 3-((hetero)aril)-alkil-8-amino-2-okso-1,3-diaza-spiro-(4.5)-dekana
SI3402782T1 (sl)	2016-01-13	2020-11-30	Grunenthal Gmbh	8-amino-2-okso-1,3-diaza-spiro-(4,5)-dekanski derivati
BR112018014302B1 (pt)	2016-01-13	2023-10-17	Grünenthal GmbH	Derivados de 3-(carboxietil)-8-amino-2-oxo-1,3-diaza-espiro-[4.5]-decano
CA3011176C (en)	2016-01-13	2023-09-19	Grunenthal Gmbh	3-((hetero-)aryl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives
CA3011180A1 (en)	2016-01-13	2017-07-20	Grunenthal Gmbh	3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives
CN113784713A (zh) *	2019-01-11	2021-12-10	纳吉斯制药股份有限公司	白三烯合成抑制剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL127065C (el) *	1964-04-22
FR2666583B1 (fr) *	1990-09-06	1994-09-09	Adir	Nouveaux derives du spiro [4.5] decane, leur procede de preparation et leurs compositions pharmaceutiques les renfermant.
WO1997000872A1 (en) *	1995-06-23	1997-01-09	F.Hoffmann-La Roche Ag	1,3,8-triaza- and 3,8-diaza-1-oxaspiro(4,5)decane derivatives

1995
- 1995-05-17 FR FR9505833A patent/FR2734265B1/fr not_active Expired - Lifetime
1996
- 1996-05-13 EP EP96401029A patent/EP0743312B1/fr not_active Expired - Lifetime
- 1996-05-13 ES ES96401029T patent/ES2142030T3/es not_active Expired - Lifetime
- 1996-05-13 AT AT96401029T patent/ATE186729T1/de not_active IP Right Cessation
- 1996-05-13 DK DK96401029T patent/DK0743312T3/da active
- 1996-05-13 DE DE69605145T patent/DE69605145T2/de not_active Expired - Fee Related
- 1996-05-15 JP JP8120277A patent/JPH08311067A/ja active Pending
- 1996-05-15 AU AU52293/96A patent/AU702587B2/en not_active Ceased
- 1996-05-15 CA CA002176668A patent/CA2176668C/fr not_active Expired - Fee Related
- 1996-05-16 US US08/649,020 patent/US5698567A/en not_active Expired - Fee Related
- 1996-05-16 NZ NZ286604A patent/NZ286604A/en unknown
- 1996-05-17 CN CN96100292A patent/CN1058014C/zh not_active Expired - Fee Related
- 1996-05-17 ZA ZA963950A patent/ZA963950B/xx unknown
- 1996-05-20 NO NO962043A patent/NO307756B1/no not_active IP Right Cessation
1999
- 1999-12-17 GR GR990403257T patent/GR3032171T3/el unknown

Also Published As

Publication number	Publication date
FR2734265A1 (fr)	1996-11-22
EP0743312A1 (fr)	1996-11-20
DE69605145D1 (de)	1999-12-23
CA2176668C (fr)	2001-11-20
EP0743312B1 (fr)	1999-11-17
NO962043D0 (no)	1996-05-20
NO962043L (no)	1996-11-18
AU5229396A (en)	1996-11-28
DE69605145T2 (de)	2000-08-17
ZA963950B (en)	1996-11-25
FR2734265B1 (fr)	1997-06-13
ATE186729T1 (de)	1999-12-15
CN1136568A (zh)	1996-11-27
NO307756B1 (no)	2000-05-22
JPH08311067A (ja)	1996-11-26
ES2142030T3 (es)	2000-04-01
CA2176668A1 (fr)	1996-11-18
AU702587B2 (en)	1999-02-25
DK0743312T3 (da)	2000-05-22
US5698567A (en)	1997-12-16
NZ286604A (en)	1998-01-26
CN1058014C (zh)	2000-11-01

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