GR3035287T3 - Insulin and amylin containing composition for the treatment of insulin deficient mammals. - Google Patents

Insulin and amylin containing composition for the treatment of insulin deficient mammals.

Info

Publication number: GR3035287T3
Authority: GR; Greece
Prior art keywords: insulin; amylin; treatment; containing composition; deficient mammals
Prior art date: 1991-05-24

Application number

GR20010400101T

Other languages

English (en)

Inventor

Timothy J Rink

Andrew A Young

Original Assignee

Amylin Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-05-24

Filing date

2001-01-24

Publication date

2001-04-30

2001-01-24 Application filed by Amylin Pharmaceuticals Inc filed Critical Amylin Pharmaceuticals Inc

2001-04-30 Publication of GR3035287T3 publication Critical patent/GR3035287T3/el

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title abstract 6
102000004877 Insulin Human genes 0.000 title abstract 3
108090001061 Insulin Proteins 0.000 title abstract 3
241000124008 Mammalia Species 0.000 title abstract 3
229940125396 insulin Drugs 0.000 title abstract 3
102000036770 Islet Amyloid Polypeptide Human genes 0.000 title abstract 2
108010041872 Islet Amyloid Polypeptide Proteins 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
230000002950 deficient Effects 0.000 title 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
229920002527 Glycogen Polymers 0.000 abstract 2
230000000694 effects Effects 0.000 abstract 2
239000008103 glucose Substances 0.000 abstract 2
229940096919 glycogen Drugs 0.000 abstract 2
238000000338 in vitro Methods 0.000 abstract 2
238000010348 incorporation Methods 0.000 abstract 2
210000002027 skeletal muscle Anatomy 0.000 abstract 2
238000000034 method Methods 0.000 abstract 1
230000004936 stimulating effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

GR20010400101T 1991-05-24 2001-01-24 Insulin and amylin containing composition for the treatment of insulin deficient mammals. GR3035287T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US70499591A	1991-05-24	1991-05-24
PCT/US1992/004351 WO1992020366A1 (en)	1991-05-24	1992-05-23	Insulin and amylin containing composition for the treatment of insulin deficient mammals

Publications (1)

Publication Number	Publication Date
GR3035287T3 true GR3035287T3 (en)	2001-04-30

Family

ID=24831674

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR20010400101T GR3035287T3 (en)	1991-05-24	2001-01-24	Insulin and amylin containing composition for the treatment of insulin deficient mammals.

Country Status (11)

Country	Link
EP (1)	EP0586592B1 (el)
JP (1)	JPH06510753A (el)
AT (1)	ATE197764T1 (el)
AU (2)	AU2169392A (el)
CA (1)	CA2109604A1 (el)
DE (1)	DE69231583T2 (el)
DK (1)	DK0586592T3 (el)
ES (1)	ES2153828T3 (el)
GR (1)	GR3035287T3 (el)
SG (1)	SG44838A1 (el)
WO (1)	WO1992020366A1 (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5656590A (en) *	1991-05-24	1997-08-12	Amylin Pharmaceuticals, Inc.	Treatment of anorexia and related states
WO2001000223A2 (en) *	1999-06-25	2001-01-04	Minimed Inc.	Multiple agent diabetes therapy
AU2002248464A1 (en)	2001-02-21	2002-09-12	Medtronic Minimed, Inc.	Stabilized insulin formulations
US6737401B2 (en)	2001-06-28	2004-05-18	Metronic Minimed, Inc.	Methods of evaluating protein formulation stability and surfactant-stabilized insulin formulations derived therefrom

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8720115D0 (en) *	1987-08-26	1987-09-30	Cooper G J S	Treatment of diabetes mellitus
GB8915712D0 (en) *	1989-07-08	1989-08-31	Macintyre Iain	Medical treatment

1992
- 1992-05-23 AU AU21693/92A patent/AU2169392A/en not_active Abandoned
- 1992-05-23 WO PCT/US1992/004351 patent/WO1992020366A1/en not_active Ceased
- 1992-05-23 DK DK92913644T patent/DK0586592T3/da active
- 1992-05-23 DE DE69231583T patent/DE69231583T2/de not_active Expired - Lifetime
- 1992-05-23 AT AT92913644T patent/ATE197764T1/de active
- 1992-05-23 SG SG1996008450A patent/SG44838A1/en unknown
- 1992-05-23 ES ES92913644T patent/ES2153828T3/es not_active Expired - Lifetime
- 1992-05-23 CA CA002109604A patent/CA2109604A1/en not_active Abandoned
- 1992-05-23 EP EP92913644A patent/EP0586592B1/en not_active Expired - Lifetime
- 1992-05-23 JP JP5500328A patent/JPH06510753A/ja active Pending
1996
- 1996-08-07 AU AU61964/96A patent/AU6196496A/en not_active Abandoned
2001
- 2001-01-24 GR GR20010400101T patent/GR3035287T3/el unknown

Also Published As

Publication number	Publication date
DK0586592T3 (da)	2000-12-27
JPH06510753A (ja)	1994-12-01
AU6196496A (en)	1996-10-10
DE69231583T2 (de)	2001-03-29
ES2153828T3 (es)	2001-03-16
CA2109604A1 (en)	1992-11-26
DE69231583D1 (de)	2001-01-04
WO1992020366A1 (en)	1992-11-26
EP0586592A1 (en)	1994-03-16
AU2169392A (en)	1992-12-30
SG44838A1 (en)	1997-12-19
EP0586592B1 (en)	2000-11-29
ATE197764T1 (de)	2000-12-15

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