GR860072B - New process for the preparation of certain steroids especially intermediates for the preparation of proligestone and related compounds and new intermediates formed in this process - Google Patents

New process for the preparation of certain steroids especially intermediates for the preparation of proligestone and related compounds and new intermediates formed in this process

Info

Publication number
GR860072B
GR860072B GR860072A GR860100072A GR860072B GR 860072 B GR860072 B GR 860072B GR 860072 A GR860072 A GR 860072A GR 860100072 A GR860100072 A GR 860100072A GR 860072 B GR860072 B GR 860072B
Authority
GR
Greece
Prior art keywords
preparation
new
intermediates
proligestone
related compounds
Prior art date
Application number
GR860072A
Other languages
Greek (el)
English (en)
Inventor
Smid Peter Max
Zoest Willem Van Johan
Weber Pieter Gijsbert
Marx Arthur Friedrich
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of GR860072B publication Critical patent/GR860072B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
GR860072A 1985-01-14 1986-01-13 New process for the preparation of certain steroids especially intermediates for the preparation of proligestone and related compounds and new intermediates formed in this process GR860072B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP85200022A EP0188010A1 (en) 1985-01-14 1985-01-14 New process for the preparation of certain steroids, especially intermediates for the preparation of proligestone and related compounds, and new intermediates formed in this process

Publications (1)

Publication Number Publication Date
GR860072B true GR860072B (en) 1986-05-14

Family

ID=8193986

Family Applications (1)

Application Number Title Priority Date Filing Date
GR860072A GR860072B (en) 1985-01-14 1986-01-13 New process for the preparation of certain steroids especially intermediates for the preparation of proligestone and related compounds and new intermediates formed in this process

Country Status (12)

Country Link
US (1) US5093502A (da)
EP (2) EP0188010A1 (da)
JP (1) JPS61172896A (da)
AU (1) AU584158B2 (da)
CA (1) CA1321576C (da)
DE (1) DE3665721D1 (da)
DK (1) DK14286A (da)
ES (1) ES8707255A1 (da)
GR (1) GR860072B (da)
IE (1) IE58702B1 (da)
NZ (1) NZ214798A (da)
PT (1) PT81829B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6378196U (da) * 1986-11-10 1988-05-24
US5364847A (en) * 1989-03-10 1994-11-15 Endorecherche Inhibitors of sex steroid biosynthesis and methods for their production and use
US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
ES2189784T3 (es) * 1989-07-07 2003-07-16 Endorech Inc Procedimiento para el tratamiento de enfermedades relacionadas con adrogenos.
AU5856090A (en) * 1989-07-07 1991-02-06 Endorecherche Inc. Androgen derivatives for use in the inhibition of sex steroid activity
JPH07506575A (ja) * 1992-05-21 1995-07-20 アンドルシェルシュ・インコーポレイテッド テストステロン５α−レダクターゼ活性の阻害剤
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
US20030022036A1 (en) * 2001-07-25 2003-01-30 Ballard Power Systems Inc. Fuel cell controller self inspection
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
RU2407800C1 (ru) * 2009-08-07 2010-12-27 Центр "Биоинженерия" РАН, ООО "НПК "СКиФФ" СПОСОБ ПОЛУЧЕНИЯ 14α-ГИДРОКСИПРОИЗВОДНЫХ Δ4-3,17-ДИКЕТО-АНДРОСТЕНОВ
CN102617692A (zh) * 2011-01-31 2012-08-01 北京紫竹药业有限公司 甾体化合物及其制备方法和用途
CN104628806A (zh) * 2012-01-19 2015-05-20 华润紫竹药业有限公司 甾体化合物及其制备方法和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3243355A (en) * 1965-07-30 1966-03-29 American Cyanamid Co Method of hydroxylating 19-nor-androstenedione
NL6703781A (da) * 1967-03-13 1968-09-16
GB1277886A (en) * 1968-09-11 1972-06-14 Koninklijke Gist Spiritus Androstenones
US3812105A (en) * 1968-09-11 1974-05-21 Koninklijke Gist Spiritus 19-nor-progesterone derivatives
US4585591A (en) * 1980-12-10 1986-04-29 Mitsubishi Chemical Industries, Ltd. 17β-ethynylsteroids and process for preparing same
US4557867A (en) * 1984-01-25 1985-12-10 The Upjohn Company 11β-Difluoromethyl and (E)- and (Z)-11-fluoromethylene steriods
US4600538A (en) * 1984-08-02 1986-07-15 The Upjohn Company Corticosteroids from 17-keto steroids via 20-cyano-Δ17 (20)-pregnanes

Also Published As

Publication number Publication date
ES550862A0 (es) 1987-07-16
US5093502A (en) 1992-03-03
ES8707255A1 (es) 1987-07-16
AU584158B2 (en) 1989-05-18
IE860088L (en) 1986-07-14
EP0189951B1 (en) 1989-09-20
DE3665721D1 (en) 1989-10-26
PT81829A (de) 1986-02-01
DK14286D0 (da) 1986-01-13
AU5225586A (en) 1986-07-17
EP0188010A1 (en) 1986-07-23
CA1321576C (en) 1993-08-24
JPS61172896A (ja) 1986-08-04
EP0189951A1 (en) 1986-08-06
DK14286A (da) 1986-07-15
NZ214798A (en) 1988-09-29
IE58702B1 (en) 1993-11-03
PT81829B (pt) 1987-11-30

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