GR862436B - Method for preparing conjugate compounds of vinblastine and its derivatives and pharmaceutical compositions containing the conjucate compounds - Google Patents

Method for preparing conjugate compounds of vinblastine and its derivatives and pharmaceutical compositions containing the conjucate compounds

Info

Publication number
GR862436B
GR862436B GR862436A GR860102436A GR862436B GR 862436 B GR862436 B GR 862436B GR 862436 A GR862436 A GR 862436A GR 860102436 A GR860102436 A GR 860102436A GR 862436 B GR862436 B GR 862436B
Authority
GR
Greece
Prior art keywords
compounds
vinblastine
derivatives
image
group
Prior art date
Application number
GR862436A
Other languages
Greek (el)
English (en)
Inventor
Trouet Andre Benoit Lenon
Rao Kandukuri Sivapras Bushana
Hannart Jean-Alfred Alphonse
Dejonghe Jean-Paul
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU86157A external-priority patent/LU86157A1/fr
Application filed by Omnichem Sa filed Critical Omnichem Sa
Publication of GR862436B publication Critical patent/GR862436B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6805Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
GR862436A 1985-11-12 1986-09-24 Method for preparing conjugate compounds of vinblastine and its derivatives and pharmaceutical compositions containing the conjucate compounds GR862436B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU86157A LU86157A1 (fr) 1985-11-12 1985-11-12 Nouveau procede de fabrication de conjugues de la vinblastine et de ses derives
EP86870042A EP0222722B1 (de) 1985-11-12 1986-04-08 Konjugate von Vinblastin und seine Derivate, Verfahren zur Herstellung derselben und diese Konjugate enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
GR862436B true GR862436B (en) 1986-12-23

Family

ID=26106792

Family Applications (1)

Application Number Title Priority Date Filing Date
GR862436A GR862436B (en) 1985-11-12 1986-09-24 Method for preparing conjugate compounds of vinblastine and its derivatives and pharmaceutical compositions containing the conjucate compounds

Country Status (6)

Country Link
AT (1) ATE89567T1 (de)
AU (1) AU577206B2 (de)
DK (1) DK164107C (de)
GR (1) GR862436B (de)
HU (1) HU196217B (de)
OA (1) OA08424A (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2508905B1 (de) * 1981-07-01 1984-01-27 Roussel Uclaf
EP0178683B1 (de) * 1984-10-19 1989-08-09 Nihon Medi-Physics Co., Ltd. Immunoassay für Estriol-3-sulfat
ZA873600B (en) * 1986-05-27 1988-12-28 Lilly Co Eli Immunoglobulin conjugates
US5094849A (en) * 1988-08-08 1992-03-10 Eli Lilly And Company Cytotoxic antibody conjugates of hydrazide derivatized vinca analogs via simple organic linkers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484691D1 (de) * 1983-04-29 1991-07-18 Omnichem Sa Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Also Published As

Publication number Publication date
DK473286A (da) 1987-05-13
AU577206B2 (en) 1988-09-15
DK164107C (da) 1992-10-05
DK164107B (da) 1992-05-11
AU6340186A (en) 1988-04-14
DK473286D0 (da) 1986-10-03
HU196217B (en) 1988-10-28
OA08424A (fr) 1988-06-30
HUT42493A (en) 1987-07-28
ATE89567T1 (de) 1993-06-15

Similar Documents

Publication Publication Date Title
EP0124502A3 (en) Conjugates of vinblastine and its derivatives, process for their preparation and pharmaceutical compositions containing these conjugates
AU579387B2 (en) New tetrapyrrole therapeutic agents
AU578781B2 (en) Novel peptide derivatives having a nitrogenous polycyclic structure, process for the preparation thereof and pharmaceutical compositions containing them
NO861722L (no) Fremgangsmaate for fremstilling av tetrapyrrol-polyaminomonocarboxylsyrederivater.
OA06421A (fr) Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
GR3001889T3 (en) Prodrug compounds, process for the preparation thereof and sustained release preparation comprising the same
SE8004792L (sv) Nya tetra- eller pentapeptider, forfaranden for framstellning av desamma och farmaceutiska kompositioner innehallande desamma
GR862436B (en) Method for preparing conjugate compounds of vinblastine and its derivatives and pharmaceutical compositions containing the conjucate compounds
DE3362009D1 (en) L-alanyl-d-isoglutaminyl-adamantyl amide, process for its preparation and pharmaceutical compositions containing this compound
SE8603589D0 (sv) Metylendioxifenantren- och stilbenderivat
GR3005533T3 (de)
NZ223333A (en) 3-phenyl-7h-thiazole (3,2-b (1,2, triazin-7-one derivatives and pharmaceutical compositions
EP0418990A3 (en) 13-bromo and 13,14-dibromo ergoline, their preparation and their use
GR3015706T3 (en) Benzylselenobenzamides of aminopyridines and picolylamines.
CA2022538A1 (fr) Derives n-(vincristinoyl-23) et n-(noranhydro-5' vinblastinoyl-23) d'acide amino-1 methylphosphonique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
NZ223664A (en) 2,3-dihydro-3-phenyl-2-oxo-benzofuranylacetic acid amide derivatives and pharmaceutical compositions
MX4658E (es) Procedimiento para preparar compuestos de acidos 3-cefem-4-carboxilicos 3,7 disubstituidos
IT1251979B (it) Derivati diazaciclici
GR3005041T3 (de)