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Application filed by Domantis LimitedfiledCriticalDomantis Limited
Publication of HK1138024ApublicationCriticalpatent/HK1138024A/en
The invention relates to anti-VEGF polypeptides and antibody single variable domains (dAbs) that are resistant to degradation by a protease, as well as antagonists comprising these. The polypeptides, dAbs and antagonists are useful for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient, as well as for treating cancer and inflammatory disease, such as arthritis.