HK1237337A1 - Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines - Google Patents

Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines Download PDF

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Publication number
HK1237337A1
HK1237337A1 HK17111163.9A HK17111163A HK1237337A1 HK 1237337 A1 HK1237337 A1 HK 1237337A1 HK 17111163 A HK17111163 A HK 17111163A HK 1237337 A1 HK1237337 A1 HK 1237337A1
Authority
HK
Hong Kong
Prior art keywords
difluoromethyl
aminopyrimidines
aminopyridines
pi3k
kinase
Prior art date
Application number
HK17111163.9A
Other languages
Chinese (zh)
Other versions
HK1237337B (en
Inventor
Vladimir Cmiljanovic
Paul Hebeisen
Florent Beaufils
Thomas Bohnacker
Denise RAGEOT
Alexander SELE
Matthias Wymann
Jean-baptiste LANGLOIS
Original Assignee
Piqur Therapeutics Ag
Universität Basel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Piqur Therapeutics Ag, Universität Basel filed Critical Piqur Therapeutics Ag
Publication of HK1237337A1 publication Critical patent/HK1237337A1/en
Publication of HK1237337B publication Critical patent/HK1237337B/en

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Abstract

The invention relates to novel phosphoinositide 3-kinase (PI3K),mammalian target of rapamycin (mTOR)and PI3K-related kinase(PIKKs)inhibitor compounds of formula (I), wherein X1, X2 and X3 are N or CH, with the proviso that at least two of X1, X2 and X3 are N; Y is N or CH, These compounds are useful, either alone or in combination with further therapeutic agents, for treating disorders mediated by lipid kinases.
HK17111163.9A 2014-11-11 2015-11-10 Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines HK1237337B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP14192617.0 2014-11-11

Publications (2)

Publication Number Publication Date
HK1237337A1 true HK1237337A1 (en) 2018-04-13
HK1237337B HK1237337B (en) 2022-01-14

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