HK58497A - Methylprednisolone/sodium carboxymethyl starch tablet composition - Google Patents

Methylprednisolone/sodium carboxymethyl starch tablet composition Download PDF

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Publication number
HK58497A
HK58497A HK58497A HK58497A HK58497A HK 58497 A HK58497 A HK 58497A HK 58497 A HK58497 A HK 58497A HK 58497 A HK58497 A HK 58497A HK 58497 A HK58497 A HK 58497A
Authority
HK
Hong Kong
Prior art keywords
methylprednisolone
tablet
super
disintegrant
tablets
Prior art date
Application number
HK58497A
Other languages
English (en)
French (fr)
Inventor
Coenraad F. Lerk
Klaas Bolhuis Gerad
Original Assignee
Pharmacia & Upjohn Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Company filed Critical Pharmacia & Upjohn Company
Publication of HK58497A publication Critical patent/HK58497A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (10)

  1. Verfahren zur Herstellung einer komprimierten Tablette oder einer Kapsel, welche eine Zusammensetzung von Methylprednisolon und mehr als 10 Gew.-% eines Superdisintegrationsmittels enthält, welches Verfahren das Naß-verarbeiten von Methylprednisolon und dem Superdisintegrationsmittel umfaßt.
  2. Verfahren nach Anspruch 1, zur Herstellung einer Tablette, welche 50 bis 700 mg Methylprednisolon enthält.
  3. Verfahren nach Anspruch 1, zur Herstellung einer Tablette, welche 100 bis 500 mg Methylprednisolon enthält.
  4. Verfahren nach Anspruch 1, zur Herstellung einer Kapsel, welche 50 bis 1000 mg Methylprednisolon enthält.
  5. Verfahren nach einem der vorhergehenden Ansprüche, worin das Superdisintegrationsmittel aus modifizierten Stärken, Natriumcroscarmallose, Calziumcarboxymethylzellulose und Crospovidon gewählt ist.
  6. Verfahren nach Anspruch 5, worin das Superdisintregrationsmittel eine modifizierte Stärke ist.
  7. Verfahren nach Anspruch 6, worin die modifizierte Stärke Natriumcarboxymethylstärke ist.
  8. Verfahren nach Anspruch 6 oder 7, worin die modifizierte Stärke in einer Menge von 10 bis 60 Gew.-% vorliegt.
  9. Verfahren nach Anspruch 8, worin die modifizierte Stärke in einer Menge von 20 bis 35 Gew.-% vorliegt.
  10. Verfahren nach einem der vorhergehenden Ansprüche, worin das Methylprednisolon mikronisiert ist.
HK58497A 1986-04-01 1997-05-01 Methylprednisolone/sodium carboxymethyl starch tablet composition HK58497A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US84662086A 1986-04-01 1986-04-01
PCT/US1987/000302 WO1987005804A1 (en) 1986-04-01 1987-02-17 Methylprednisolone/sodium carboxymethyl starch tablet composition

Publications (1)

Publication Number Publication Date
HK58497A true HK58497A (en) 1997-05-09

Family

ID=25298443

Family Applications (1)

Application Number Title Priority Date Filing Date
HK58497A HK58497A (en) 1986-04-01 1997-05-01 Methylprednisolone/sodium carboxymethyl starch tablet composition

Country Status (8)

Country Link
EP (1) EP0301006B1 (de)
JP (1) JPH01501934A (de)
KR (1) KR880701098A (de)
AU (1) AU7084587A (de)
DK (1) DK167341B1 (de)
HK (1) HK58497A (de)
NO (1) NO175884C (de)
WO (1) WO1987005804A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
SK282072B6 (sk) * 1991-01-30 2001-10-08 The Wellcome Foundation Limited Tableta s obsahom lamotrigínu dispergovateľná vo vode a spôsob jej prípravy
ES2160582T3 (es) * 1992-04-03 2001-11-16 Nippon Kayaku Kk Capsula dura de ocfosfato de citarabina.
GB9215908D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Water dispersible tablets
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
GB2292079B (en) * 1994-08-12 1998-07-15 Flexpharm Ltd Coated prednisolone preparation for the treatment of inflamatory bowel disease
SE504902C2 (sv) * 1994-11-02 1997-05-26 Diabact Ab Beredning för påvisande av Helicobacter pylori i magsäcken
US5955107A (en) * 1997-12-12 1999-09-21 Fmc Corporation Pharmaceutical suspension tablet compositions
UA72207C2 (uk) 1998-04-07 2005-02-15 Брістол- Майєрс Сквібб Фарма Компані Фармацевтична композиція ефавіренцу з добавкою дезінтегруючих агентів у вигляді швидкорозчинних капсул або таблеток та спосіб її виготовлення
US6599530B2 (en) * 1998-09-14 2003-07-29 Orion Corporation Oral compacted composition comprising catechol derivatives
DE19855203A1 (de) * 1998-11-30 2000-05-31 Kurt Heinz Bauer Coprozessiertes Polysaccharidprodukt
DE19922537A1 (de) * 1999-05-10 2000-11-16 Roland Bodmeier Darreichungsform zur Applikation in Körperöffnungen
CA2311734C (en) * 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
IL156445A0 (en) 2001-01-26 2004-01-04 Schering Corp Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
US7838029B1 (en) * 2003-07-31 2010-11-23 Watson Laboratories, Inc. Mirtazapine solid dosage forms
KR100882156B1 (ko) * 2003-08-08 2009-02-06 아지노모토 가부시키가이샤 나테글리니드 함유 제제
EP1744760B1 (de) 2004-04-22 2015-01-07 AcuCort AB Pharmazeutische zusammensetzungen für die akute glucocorticoid-therapie
PL1916995T5 (pl) 2005-07-29 2022-10-31 Stichting Groningen Centre For Drug Research Kontrolowany wartością ph impulsowy układ podawczy, sposoby przygotowania i zastosowanie
US7811604B1 (en) 2005-11-14 2010-10-12 Barr Laboratories, Inc. Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same
JP6037687B2 (ja) * 2011-07-08 2016-12-07 サノフィ株式会社 グリメピリドを含有する口腔内崩壊錠
BE1021446B1 (nl) * 2015-01-06 2015-11-24 Stasisport Pharma Nv Methylprednisolon tablet en werkwijze
CN106265568B (zh) * 2016-08-30 2018-08-10 林州中农颖泰生物肽有限公司 一种水溶性醋酸地塞米松片及其制备方法
CN109925288A (zh) * 2017-12-18 2019-06-25 江苏开元药业有限公司 一种糖皮质激素药物片剂及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2200778B2 (de) * 1971-01-13 1974-04-18 Sandoz Ag, Basel (Schweiz) Verwendung von hochmolekularem, unlöslichem, quervernetztem Polyvinylpyrrolidon als Sprengmittel in festen Arzneiformen
ATE13486T1 (de) * 1980-11-12 1985-06-15 Ciba Geigy Ag Schnellzerfallende arzneimittel-presslinge.
GB8403360D0 (en) * 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical compositions

Also Published As

Publication number Publication date
EP0301006A1 (de) 1989-02-01
NO175884B (no) 1994-09-19
DK167341B1 (da) 1993-10-18
DK624287A (da) 1987-11-27
JPH01501934A (ja) 1989-07-06
AU7084587A (en) 1987-10-20
KR880701098A (ko) 1988-07-25
NO175884C (no) 1994-12-28
WO1987005804A1 (en) 1987-10-08
DK624287D0 (da) 1987-11-27
NO874989L (no) 1987-11-30
EP0301006B1 (de) 1992-05-06
NO874989D0 (no) 1987-11-30

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Effective date: 20070216