HRP20030652A2 - Method of treating of demyelinating diseases or conditions - Google Patents

Method of treating of demyelinating diseases or conditions Download PDF

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Publication number
HRP20030652A2
HRP20030652A2 HR20030652A HRP20030652A HRP20030652A2 HR P20030652 A2 HRP20030652 A2 HR P20030652A2 HR 20030652 A HR20030652 A HR 20030652A HR P20030652 A HRP20030652 A HR P20030652A HR P20030652 A2 HRP20030652 A2 HR P20030652A2
Authority
HR
Croatia
Prior art keywords
hydrogen
compound
c6alkyl
alkyl
treatment
Prior art date
Application number
HR20030652A
Other languages
English (en)
Croatian (hr)
Inventor
P. Smith Craig
P. Rathbone Michel
Petty Margaret
Rampe David
Original Assignee
Aventis Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc. filed Critical Aventis Pharmaceuticals Inc.
Publication of HRP20030652A2 publication Critical patent/HRP20030652A2/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HR20030652A 2001-02-15 2002-02-14 Method of treating of demyelinating diseases or conditions HRP20030652A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26884601P 2001-02-15 2001-02-15
GBGB0119435.6A GB0119435D0 (en) 2001-02-15 2001-08-09 Method of treating of demyelinating diseases or conditions
PCT/US2002/005501 WO2002064126A2 (fr) 2001-02-15 2002-02-14 Methode destinee au traitement de pathologies ou de troubles lies a la demyelinisation

Publications (1)

Publication Number Publication Date
HRP20030652A2 true HRP20030652A2 (en) 2005-06-30

Family

ID=23024747

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030652A HRP20030652A2 (en) 2001-02-15 2002-02-14 Method of treating of demyelinating diseases or conditions

Country Status (39)

Country Link
US (10) US6967210B2 (fr)
EP (1) EP1368031A2 (fr)
JP (3) JP2004518711A (fr)
KR (3) KR20090005254A (fr)
CN (2) CN100522164C (fr)
AP (1) AP1749A (fr)
AR (1) AR035750A1 (fr)
AU (3) AU2002247200B9 (fr)
BR (1) BR0207272A (fr)
CA (1) CA2438712A1 (fr)
CO (1) CO5390085A1 (fr)
CR (1) CR7023A (fr)
CZ (1) CZ20032172A3 (fr)
EA (2) EA011319B1 (fr)
EC (1) ECSP024218A (fr)
EE (1) EE200300363A (fr)
GB (1) GB0119435D0 (fr)
HK (1) HK1080361B (fr)
HR (1) HRP20030652A2 (fr)
HU (1) HUP0303203A3 (fr)
IL (2) IL157341A0 (fr)
MA (1) MA26152A1 (fr)
ME (1) MEP21208A (fr)
MX (1) MXPA03006110A (fr)
MY (1) MY157745A (fr)
NO (1) NO20033622L (fr)
NZ (4) NZ527011A (fr)
OA (1) OA12549A (fr)
PA (1) PA8540101A1 (fr)
PE (1) PE20040175A1 (fr)
PL (1) PL363638A1 (fr)
SG (1) SG134170A1 (fr)
SK (1) SK10392003A3 (fr)
TR (4) TR200301330T2 (fr)
TW (1) TWI325319B (fr)
UA (2) UA80394C2 (fr)
WO (1) WO2002064126A2 (fr)
YU (1) YU62903A (fr)
ZA (1) ZA200306124B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0119435D0 (en) * 2001-02-15 2001-10-03 Aventis Pharm Prod Inc Method of treating of demyelinating diseases or conditions
ES2288641T3 (es) * 2002-12-20 2008-01-16 Dynogen Pharmaceuticals Inc. Metodo para tratar trastornos indoloros de la vejiga usando moduladores de canales del calcio de la subunidad alfa2-delta.
EP1589959A2 (fr) * 2003-01-30 2005-11-02 Dynogen Pharmaceuticals Inc. Methodes destinees a traiter les troubles du tractus urinaire inferieur au moyen de modulateurs du canal sodique
DE602004003172T2 (de) * 2003-03-21 2007-09-27 Dynogen Pharmaceuticals Inc., Waltham Verfahren zur behandlung von erkrankungen der unteren harnwege mit antimuskarinika und mit modulatoren der alpha-2-delta untereinheit des kalziumkanals
GT200500063A (es) * 2004-04-01 2005-10-14 Metodo para tratar la esquizofrenia y/o anormalidades glucoregulatorias
GB0510164D0 (en) * 2005-04-28 2005-06-22 Paradigm Therapeutics Ltd Ion channel
FR2892021B1 (fr) * 2005-10-19 2008-01-04 Urogene Traitement de l'incontinence urinaire d'effort et mixte
FR2892022B1 (fr) * 2005-10-19 2008-01-04 Urogene Sa Traitement des symptomes de l'irritation de la vessie
US8420593B1 (en) * 2006-06-16 2013-04-16 Landon C. G. Miller Compositions and methods for regulating membrane potential
DE102008044844B4 (de) * 2008-08-28 2018-08-30 Siemens Healthcare Gmbh Verfahren zur Ermittlung einer Schwächungskarte zur Verwendung in der Positronenemissionstomographie und von Homogenitätsinformationen des Magnetresonanzmagnetfeldes
WO2011118364A1 (fr) * 2010-03-26 2011-09-29 Semiconductor Energy Laboratory Co., Ltd. Dispositif semi-conducteur
WO2012009204A1 (fr) * 2010-07-15 2012-01-19 The Trustees Of Columbia University In The City Of New York Procédés pour le diagnostic et le traitement de troubles commotionnels
JP2014503596A (ja) * 2011-01-28 2014-02-13 アコーダ セラピューティクス,インコーポレーテッド 脳性麻痺を治療するためのカリウムチャネル遮断薬の使用
TWI592156B (zh) * 2011-10-04 2017-07-21 艾可達醫療公司 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法
WO2017151409A1 (fr) 2016-02-29 2017-09-08 University Of Florida Research Foundation, Incorporated Méthodes de chimiothérapie
US11730769B2 (en) 2017-12-22 2023-08-22 Children's Medical Center Corporation Compositions and methods for Williams Syndrome (WS) therapy
CN116723870A (zh) * 2021-01-20 2023-09-08 拉什大学医学中心 球形细胞脑白质营养不良症或克拉伯病的改良治疗

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970218A (en) * 1987-04-24 1990-11-13 Hoechst-Roussel Pharmaceuticals Inc. N-(pyridinyl)-1H-indol-1-amines
ATE115143T1 (de) * 1987-04-24 1994-12-15 Hoechst Roussel Pharma N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel.
US4880822A (en) * 1987-04-24 1989-11-14 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyridinyl)-1H-indol-1-amines
DK0415103T3 (da) 1989-08-02 1995-06-19 Hoechst Roussel Pharma 2,3-Dihydro-1-(pyridinylamino)-indoler, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
US5214038A (en) * 1991-04-15 1993-05-25 Hoechst-Roussel Pharmaceuticals Inc. 1-(pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles and intermediates for the preparation thereof
DE4325491A1 (de) * 1993-07-29 1995-02-02 Boehringer Ingelheim Kg Verwendung von zentral wirksamen alpha-2-Agonisten zur Hemmung des Postaggressionsstoffwechsels
US5459274A (en) 1994-05-13 1995-10-17 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines
US5565475A (en) 1994-11-08 1996-10-15 Muhlhauser; Mark A. Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives
EP0731108A1 (fr) 1995-03-10 1996-09-11 Boehringer Mannheim Gmbh Procédé de fabrication d'un agent thérapeutique pour la régénération d'oligodendrocytes
FR2754147B1 (fr) 1996-10-03 2000-02-04 Mbh Technologies Sa Installation et procede pour le traitement de carcasses
PT1056754E (pt) * 1998-01-29 2004-03-31 Bristol Myers Squibb Co Derivados fosfatados de 1,3,4-oxadiazolona de diarilo
AU5483500A (en) 1999-07-09 2001-01-30 Ortho-Mcneil Pharmaceutical, Inc. Neurotrophic 2-azetidinecarboxylic acid derivatives, and related compositions and methods
GB0119435D0 (en) * 2001-02-15 2001-10-03 Aventis Pharm Prod Inc Method of treating of demyelinating diseases or conditions

Also Published As

Publication number Publication date
KR20040014459A (ko) 2004-02-14
CZ20032172A3 (cs) 2004-01-14
MEP21208A (en) 2010-06-10
EA200300882A1 (ru) 2003-12-25
US20050234105A1 (en) 2005-10-20
IL157341A (en) 2010-11-30
MXPA03006110A (es) 2005-07-01
KR20090005254A (ko) 2009-01-12
EE200300363A (et) 2003-10-15
US20060025452A1 (en) 2006-02-02
CR7023A (es) 2003-11-17
AU2008201179B2 (en) 2009-08-20
AP1749A (en) 2007-06-13
MY157745A (en) 2016-07-15
TR200800692T2 (tr) 2008-03-21
US20040157888A1 (en) 2004-08-12
HK1080361B (zh) 2009-10-30
NO20033622L (no) 2003-10-06
US7179821B2 (en) 2007-02-20
MA26152A1 (fr) 2004-07-01
JP2009185045A (ja) 2009-08-20
PE20040175A1 (es) 2004-03-29
US20050159456A1 (en) 2005-07-21
IL157341A0 (en) 2004-02-19
US20090270458A1 (en) 2009-10-29
US20090209595A1 (en) 2009-08-20
KR100951540B1 (ko) 2010-04-09
NZ539159A (en) 2006-11-30
HK1080361A1 (zh) 2006-04-28
CO5390085A1 (es) 2004-04-30
EA011319B1 (ru) 2009-02-27
US20040157889A1 (en) 2004-08-12
WO2002064126A2 (fr) 2002-08-22
YU62903A (sh) 2006-05-25
EA012409B1 (ru) 2009-10-30
UA80394C2 (en) 2007-09-25
CA2438712A1 (fr) 2002-08-22
AU2002247200B9 (en) 2008-07-10
JP2010120958A (ja) 2010-06-03
AU2008201179A1 (en) 2008-04-03
US20090209594A1 (en) 2009-08-20
NO20033622D0 (no) 2003-08-14
AU2009238332A1 (en) 2009-12-10
WO2002064126A3 (fr) 2003-02-20
EP1368031A2 (fr) 2003-12-10
AP2003002834A0 (en) 2003-09-30
SK10392003A3 (sk) 2004-01-08
TWI325319B (en) 2010-06-01
EA200600896A1 (ru) 2006-08-25
US7534803B2 (en) 2009-05-19
CN1679564A (zh) 2005-10-12
CN1529598A (zh) 2004-09-15
TR200800691T2 (tr) 2008-03-21
PA8540101A1 (es) 2003-09-05
GB0119435D0 (en) 2001-10-03
JP2004518711A (ja) 2004-06-24
US7230015B2 (en) 2007-06-12
HUP0303203A2 (hu) 2003-12-29
ZA200306124B (en) 2004-11-08
HUP0303203A3 (en) 2007-11-28
US20090281147A1 (en) 2009-11-12
OA12549A (en) 2006-06-05
ECSP024218A (es) 2003-09-24
UA88773C2 (ru) 2009-11-25
KR100951542B1 (ko) 2010-04-09
NZ544720A (en) 2007-08-31
SG134170A1 (en) 2007-08-29
PL363638A1 (en) 2004-11-29
KR20090005255A (ko) 2009-01-12
AR035750A1 (es) 2004-07-07
NZ527011A (en) 2005-07-29
US20030105150A1 (en) 2003-06-05
CN100522164C (zh) 2009-08-05
US6967210B2 (en) 2005-11-22
BR0207272A (pt) 2004-02-10
AU2002247200B2 (en) 2007-12-13
TR200301330T2 (tr) 2004-12-21
NZ556697A (en) 2009-01-31
TR200800693T2 (tr) 2008-07-21

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