HRP20040090A2 - Arylsulfonyl derivatives with 5-ht6 receptor affinity - Google Patents

Arylsulfonyl derivatives with 5-ht6 receptor affinity

Info

Publication number: HRP20040090A2
Authority: HR; Croatia
Prior art keywords: sub; receptor affinity; arylsulfonyl derivatives; compounds; methods
Prior art date: 2001-08-10

Application number

Other languages

English (en)

Inventor

Jacob Berger

Robin Douglas Clark

Shu-Hai Zhao

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-10

Filing date

2002-08-05

Publication date

2004-12-31

2002-08-05 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2004-12-31 Publication of HRP20040090A2 publication Critical patent/HRP20040090A2/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Physical Education & Sports Medicine (AREA)
Anesthesiology (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Compositions Of Macromolecular Compounds (AREA)
Photoreceptors In Electrophotography (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

HRP20040090 2001-08-10 2002-08-05 Arylsulfonyl derivatives with 5-ht6 receptor affinity HRP20040090A2 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US31150401P	2001-08-10	2001-08-10
US38471102P	2002-05-31	2002-05-31
PCT/EP2002/008696 WO2003014097A1 (en)	2001-08-10	2002-08-05	Arylsulfonyl derivatives with 5-ht6 receptor affinity

Publications (1)

Publication Number	Publication Date
HRP20040090A2 true HRP20040090A2 (en)	2004-12-31

Family

ID=26977917

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HRP20040090 HRP20040090A2 (en)	2001-08-10	2002-08-05	Arylsulfonyl derivatives with 5-ht<sub>6</sub> receptor affinity

Country Status (20)

Country	Link
US (1)	US6825202B2 (de)
EP (1)	EP1423106B1 (de)
JP (1)	JP4187650B2 (de)
KR (1)	KR100608417B1 (de)
CN (1)	CN1254469C (de)
AT (1)	ATE417838T1 (de)
AU (1)	AU2002340804B2 (de)
CA (1)	CA2456250A1 (de)
CO (1)	CO5550439A2 (de)
DE (1)	DE60230424D1 (de)
ES (1)	ES2316619T3 (de)
HR (1)	HRP20040090A2 (de)
HU (1)	HUP0401235A2 (de)
IL (1)	IL159880A0 (de)
MX (1)	MXPA04001250A (de)
NO (1)	NO326497B1 (de)
NZ (1)	NZ530742A (de)
PL (1)	PL373397A1 (de)
RU (1)	RU2268884C2 (de)
WO (1)	WO2003014097A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
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SI1497266T1 (sl)	2002-03-27	2008-10-31	Glaxo Group Ltd	Derivati kinolina in njihova uporaba kot ligandi 5-ht6
EP1562918B1 (de) *	2002-11-08	2008-01-16	F. Hoffmann-La Roche Ag	Substituierte benzoxazinones und ihre verwendung
TWI289141B (en)	2003-03-11	2007-11-01	Hoffmann La Roche F. Ag.	Quinolinone derivatives and uses thereof
GB0305575D0 (en) *	2003-03-11	2003-04-16	Glaxo Group Ltd	Novel compounds
EP1558582B1 (de)	2003-07-22	2005-12-21	Arena Pharmaceuticals, Inc.	Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen
WO2006062481A1 (en) *	2004-12-09	2006-06-15	Biovitrum Ab	New benzofuran derivatives and their use in the treatment of obesity, type ii diabetes and cns disorders .
PT1831159E (pt) *	2004-12-21	2010-03-03	Hoffmann La Roche	Derivados de tetralina e de indano e as suas utilizações
EP1695971A1 (de) *	2004-12-30	2006-08-30	Laboratorios Del Dr. Esteve, S.A.	Substituierte Phenylpiparazinverbindungen, deren Herstellung und Verwendung in Medikamenten
EP2254564A1 (de)	2007-12-12	2010-12-01	Glaxo Group Limited	Kombinationen mit 3-phenylsulfonyl-8-piperazinyl-1yl-chinolin
US20110021538A1 (en)	2008-04-02	2011-01-27	Arena Pharmaceuticals, Inc.	Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
WO2010062321A1 (en)	2008-10-28	2010-06-03	Arena Pharmaceuticals, Inc.	Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
UA107080C2 (uk) *	2009-04-30	2014-11-25		Сполуки n-феніл(піперазиніл або гомопіперазиніл)бензолсульфонаміду або бензолсульфонілфеніл(піперазину або гомопіперазину), придатні для лікування захворювань, які реагують на модулювання рецептора 5-ht6 серотоніну
US8343959B2 (en)	2009-04-30	2013-01-01	Abbott Gmbh & Co. Kg	N-phenyl-(piperazinyl or homopiperazinyl)-benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor
US8183237B2 (en)	2009-04-30	2012-05-22	Abbott Laboratories	Benzenesulfonanilide compounds suitable for treating disorders that respond to modulation of the serotonin 5-HT6 receptor
WO2012059431A1 (en)	2010-11-01	2012-05-10	Abbott Gmbh & Co. Kg	Benzenesulfonyl or sulfonamide compounds suitable for treating disorders that respond to the modulation of the serotonin 5-ht6 receptor
WO2012059432A1 (en)	2010-11-01	2012-05-10	Abbott Gmbh & Co. Kg	N-phenyl-(homo)piperazinyl-benzenesulfonyl or benzenesulfonamide compounds suitable for treating disorders that respond to the modulation of the 5-ht6 receptor
WO2015090233A1 (en)	2013-12-20	2015-06-25	Sunshine Lake Pharma Co., Ltd.	Aromatic heterocyclic compounds and their application in pharmaceuticals
CN105085436B (zh)	2014-04-19	2019-08-16	广东东阳光药业有限公司	磺酰胺类衍生物及其在药物上的应用
HK1245660A1 (zh)	2015-06-12	2018-08-31	Axovant Sciences Gmbh	有用於预防和治疗rem睡眠行为障碍的二芳基脲和芳基脲衍生物
WO2017011767A2 (en)	2015-07-15	2017-01-19	Axovant Sciences Ltd.	Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SU551871A1 (ru) *	1974-03-26	1981-09-07	Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латсср	2-Арилпиперазино-2-фенилинданоны,обладающие психотропными свойствами
DZ2376A1 (fr) *	1996-12-19	2002-12-28	Smithkline Beecham Plc	Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
HUP0003073A3 (en) *	1997-07-11	2002-10-28	Smithkline Beecham Plc	Benzenesulfonamide derivatives, process for producing them and their use as medicines
ATE236136T1 (de)	1998-01-16	2003-04-15	Hoffmann La Roche	Benzosulfonderivate
GB9801392D0 (en) *	1998-01-22	1998-03-18	Smithkline Beecham Plc	Novel compounds
GB9803411D0 (en)	1998-02-18	1998-04-15	Smithkline Beecham Plc	Novel compounds
GB9818914D0 (en)	1998-08-28	1998-10-21	Smithkline Beecham Plc	Use
GB9818916D0 (en)	1998-08-28	1998-10-21	Smithkline Beecham Plc	Use
GB9926302D0 (en)	1999-11-05	2000-01-12	Smithkline Beecham Plc	Novel compounds
PE20020063A1 (es) *	2000-06-20	2002-01-30	Upjohn Co	Bis-arilsulfonas como ligandos del receptor de 5-ht

2002
- 2002-08-05 CA CA002456250A patent/CA2456250A1/en not_active Abandoned
- 2002-08-05 KR KR1020047001985A patent/KR100608417B1/ko not_active Expired - Fee Related
- 2002-08-05 CN CNB02815679XA patent/CN1254469C/zh not_active Expired - Fee Related
- 2002-08-05 HU HU0401235A patent/HUP0401235A2/hu unknown
- 2002-08-05 WO PCT/EP2002/008696 patent/WO2003014097A1/en not_active Ceased
- 2002-08-05 RU RU2004107261/04A patent/RU2268884C2/ru not_active IP Right Cessation
- 2002-08-05 AU AU2002340804A patent/AU2002340804B2/en not_active Ceased
- 2002-08-05 ES ES02774499T patent/ES2316619T3/es not_active Expired - Lifetime
- 2002-08-05 AT AT02774499T patent/ATE417838T1/de not_active IP Right Cessation
- 2002-08-05 NZ NZ530742A patent/NZ530742A/en unknown
- 2002-08-05 HR HRP20040090 patent/HRP20040090A2/xx not_active Application Discontinuation
- 2002-08-05 DE DE60230424T patent/DE60230424D1/de not_active Expired - Lifetime
- 2002-08-05 MX MXPA04001250A patent/MXPA04001250A/es active IP Right Grant
- 2002-08-05 PL PL02373397A patent/PL373397A1/xx unknown
- 2002-08-05 IL IL15988002A patent/IL159880A0/xx unknown
- 2002-08-05 JP JP2003519047A patent/JP4187650B2/ja not_active Expired - Fee Related
- 2002-08-05 EP EP02774499A patent/EP1423106B1/de not_active Expired - Lifetime
- 2002-08-09 US US10/215,769 patent/US6825202B2/en not_active Expired - Fee Related
2004
- 2004-02-05 CO CO04009120A patent/CO5550439A2/es not_active Application Discontinuation
- 2004-02-09 NO NO20040589A patent/NO326497B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO20040589L (no)	2004-03-19
ES2316619T3 (es)	2009-04-16
DE60230424D1 (en)	2009-01-29
RU2004107261A (ru)	2005-09-10
NO326497B1 (no)	2008-12-15
HUP0401235A2 (hu)	2004-10-28
EP1423106A1 (de)	2004-06-02
HK1070054A1 (en)	2005-06-10
RU2268884C2 (ru)	2006-01-27
CN1254469C (zh)	2006-05-03
PL373397A1 (en)	2005-08-22
KR100608417B1 (ko)	2006-08-02
US20030069254A1 (en)	2003-04-10
JP4187650B2 (ja)	2008-11-26
JP2005502649A (ja)	2005-01-27
MXPA04001250A (es)	2004-05-27
CO5550439A2 (es)	2005-08-31
NZ530742A (en)	2007-07-27
WO2003014097A1 (en)	2003-02-20
CA2456250A1 (en)	2003-02-20
EP1423106B1 (de)	2008-12-17
CN1541210A (zh)	2004-10-27
KR20040023738A (ko)	2004-03-18
AU2002340804B2 (en)	2008-04-03
US6825202B2 (en)	2004-11-30
ATE417838T1 (de)	2009-01-15
IL159880A0 (en)	2004-06-20

Publication	Publication Date	Title
IL159880A0 (en)	2004-06-20	Arylsulfonyl derivatives with 5-ht6 receptor affinity
MXPA03011638A (es)	2004-04-02	Nuevos derivados de 4-piperazinil indol con afinidad por el receptor 5-ht6.
BG108420A (en)	2005-02-28	New indole derivatives with 5-ht6 receptor affinity
PL367618A1 (en)	2005-03-07	5-halo-tryptamine derivatives used as ligands of the 5-ht6 and/or 5-ht 7 serotonin receptors
AP1739A (en)	2007-05-09	Azaindoles
MXPA02012033A (es)	2003-04-25	Derivados de 2-aminocarbonil-9h-purina.
PL361361A1 (en)	2004-10-04	Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists
MXPA04007414A (es)	2004-10-11	Indoles sustituidos como agonistas alfa-1.
BG107171A (bg)	2003-07-31	Производни на пурин
DE60208568D1 (de)	2006-03-30	Prostaglandinanaloga als ep4-rezeptoragonisten
SE9904508D0 (sv)	1999-12-09	New compounds
SE0302760D0 (sv)	2003-10-20	New compounds
PL361282A1 (en)	2004-10-04	Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists
WO2005060959A8 (en)	2006-01-12	Pyrazole derivatives and use thereof as orexin receptor antagonists
PL374019A1 (en)	2005-09-19	Benzoxazine derivatives as 5-ht6 modulators and uses thereof
SE0102055D0 (sv)	2001-06-08	New Compounds
MXPA04005426A (es)	2004-10-11	Derivados de pirazol de anillos fuisionados.
ATE202342T1 (de)	2001-07-15	5-(4-subst.-piperidinyl-1)-3-aryl-pentansäure derivate als tachykinin rezeptor antagonisten
MXPA04005076A (es)	2004-08-19	Derivados de 4-piperidinil alquilamina como antagonistas del receptor muscarinico.
CA2490115A1 (en)	2003-12-31	Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
PL1660484T3 (pl)	2009-02-27	Metyloindole i metylopirolopirydyny jako agoniści receptora adrenergicznego α-1
CA2490002A1 (en)	2003-12-31	Novel tetracyclic arylcarbonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
SE0301371D0 (sv)	2003-05-09	New Compounds
EE05300B1 (et)	2010-06-15	Akrloldistamtsiini derivaati sisaldav farmatseutiline kompositsioon, derivaadi kasutamine tuumorivastase ravimi valmistamiseks ning kombineeritud ravimpreparaat
AU2001295837A1 (en)	2002-05-15	Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis

Legal Events

Date	Code	Title	Description
2004-12-31	A1OB	Publication of a patent application
2005-06-16	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2008-07-31	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20080731 Year of fee payment: 7
2009-05-29	OBST	Application withdrawn

HRP20040090A2 - Arylsulfonyl derivatives with 5-ht<sub>6</sub> receptor affinity - Google Patents