HRP20041042A2 - Novi supstituirani derivati sulfamata kao antikonvulzivi - Google Patents

Novi supstituirani derivati sulfamata kao antikonvulzivi

Info

Publication number
HRP20041042A2
HRP20041042A2 HR20041042A HRP20041042A HRP20041042A2 HR P20041042 A2 HRP20041042 A2 HR P20041042A2 HR 20041042 A HR20041042 A HR 20041042A HR P20041042 A HRP20041042 A HR P20041042A HR P20041042 A2 HRP20041042 A2 HR P20041042A2
Authority
HR
Croatia
Prior art keywords
convulsives
new substituted
sulfamate derivatives
derivatives
substituted sulfamate
Prior art date
Application number
HR20041042A
Other languages
English (en)
Croatian (hr)
Inventor
Abdel-Magid Ahmed
Maryanoff Cynthia
Mehrman Steven
Sorgi Kirk
Villani Frank
P. Kordik Cheryl
B. Reitz Allen
Eliot Maryanoff Bruce
Original Assignee
Ortho-Mcneil-Janssen Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho-Mcneil-Janssen Pharmaceuticals filed Critical Ortho-Mcneil-Janssen Pharmaceuticals
Publication of HRP20041042A2 publication Critical patent/HRP20041042A2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Saccharide Compounds (AREA)
HR20041042A 2002-05-13 2003-05-09 Novi supstituirani derivati sulfamata kao antikonvulzivi HRP20041042A2 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37801702P 2002-05-13 2002-05-13
PCT/US2003/014796 WO2003097656A2 (fr) 2002-05-13 2003-05-09 Nouveaux derivés anticonvulsifs à substitution sulfamate

Publications (1)

Publication Number Publication Date
HRP20041042A2 true HRP20041042A2 (hr) 2009-04-30

Family

ID=29549890

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20041042A HRP20041042A2 (hr) 2002-05-13 2003-05-09 Novi supstituirani derivati sulfamata kao antikonvulzivi

Country Status (19)

Country Link
US (2) US7060725B2 (fr)
EP (1) EP1506212A2 (fr)
JP (1) JP2005526852A (fr)
CN (1) CN1665828B (fr)
AR (1) AR040412A1 (fr)
AU (1) AU2003232112B2 (fr)
BR (1) BR0309964A (fr)
CA (1) CA2485966A1 (fr)
HR (1) HRP20041042A2 (fr)
IL (1) IL165108A0 (fr)
MX (1) MXPA04011232A (fr)
NO (1) NO20045369L (fr)
NZ (1) NZ537139A (fr)
PL (1) PL373910A1 (fr)
RU (1) RU2328502C2 (fr)
TW (1) TWI281472B (fr)
UA (1) UA78566C2 (fr)
WO (1) WO2003097656A2 (fr)
ZA (1) ZA200409989B (fr)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060088886A1 (en) * 2004-10-25 2006-04-27 Anlong Ouyang Topiramate analogs
US7638291B2 (en) * 2004-10-25 2009-12-29 Seradyn, Inc. Immunoassays for topiramate
WO2007099388A1 (fr) * 2006-03-01 2007-09-07 Glade Organics Private Limited Procédé amélioré de fabrication du topiramate
US9303038B2 (en) 2011-09-06 2016-04-05 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological diseases
US9738631B2 (en) 2012-05-07 2017-08-22 Cellix Bio Private Limited Compositions and methods for the treatment of neurological disorders
WO2013167990A1 (fr) 2012-05-07 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de la dépression
JP2015522531A (ja) 2012-05-07 2015-08-06 セリックスビオ プライヴェート リミテッド 神経筋疾患及び神経変性疾患の治療のための組成物及び方法
US9309233B2 (en) 2012-05-08 2016-04-12 Cellix Bio Private Limited Compositions and methods for the treatment of blood clotting disorders
US9266823B2 (en) 2012-05-08 2016-02-23 Cellix Bio Private Limited Compositions and methods for the treatment of parkinson's disease
US9403826B2 (en) 2012-05-08 2016-08-02 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory disorders
US9522884B2 (en) 2012-05-08 2016-12-20 Cellix Bio Private Limited Compositions and methods for the treatment of metabolic disorders
US9434704B2 (en) 2012-05-08 2016-09-06 Cellix Bio Private Limited Compositions and methods for the treatment of neurological degenerative disorders
WO2013168002A1 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement d'affections neurologiques
WO2013168015A1 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes pour le traitement de l'asthme et de l'allergie
US9242939B2 (en) 2012-05-10 2016-01-26 Cellix Bio Private Limited Compositions and methods for the treatment of respiratory disorders
WO2013167997A2 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement du syndrome métabolique
US9321775B2 (en) 2012-05-10 2016-04-26 Cellix Bio Private Limited Compositions and methods for the treatment of moderate to severe pain
US9339484B2 (en) 2012-05-10 2016-05-17 Cellix Bio Private Limited Compositions and methods for the treatment of restless leg syndrome and fibromyalgia
US9499527B2 (en) 2012-05-10 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of familial amyloid polyneuropathy
SG11201407318UA (en) 2012-05-10 2014-12-30 Cellix Bio Private Ltd Compositions and methods for the treatment of metabolic syndrome
WO2013168000A1 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de la douleur sévère
WO2013168011A1 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de la douleur chronique
WO2013168004A2 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de la douleur fibromyalgique
US9315461B2 (en) 2012-05-10 2016-04-19 Cellix Bio Private Limited Compositions and methods for the treatment of neurologic diseases
US9499526B2 (en) 2012-05-10 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of neurologic diseases
AU2013264896A1 (en) 2012-05-23 2014-11-27 Cellixbio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9498461B2 (en) 2012-05-23 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
WO2013175347A2 (fr) 2012-05-23 2013-11-28 Mahesh Kandula Compositions et méthodes pour le traitement de troubles respiratoires
WO2013175344A2 (fr) 2012-05-23 2013-11-28 Mahesh Kandula Compositions et méthodes pour le traitement de la parodontite et de la polyarthrite rhumatoïde
AU2013264820A1 (en) 2012-05-23 2014-11-27 Cellixbio Private Limited Compositions and methods for treatment of mucositis
WO2013175376A2 (fr) 2012-05-23 2013-11-28 Mahesh Kandula Compositions et méthodes de traitement de la douleur locale
US9108942B1 (en) 2014-11-05 2015-08-18 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
WO2014020480A2 (fr) 2012-08-03 2014-02-06 Mahesh Kandula Compositions et méthodes pour le traitement de la migraine et de maladies neurologiques
US9624168B2 (en) 2012-09-06 2017-04-18 Cellix Bio Private Limited Compositions and methods for the treatment inflammation and lipid disorders
CA2873029A1 (fr) 2012-09-08 2014-03-13 Cellixbio Private Limited Compositions et methodes de traitement d'une inflammation et de troubles lipidiques
HUE038423T2 (hu) 2012-12-07 2018-10-29 Glycomimetics Inc E-szelektin antagonistákat felhasználó vegyületek, készítmények és eljárások vérképzõ sejtek mobilizációjára
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
US9333187B1 (en) 2013-05-15 2016-05-10 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
SG11201509782TA (en) 2013-06-04 2015-12-30 Cellix Bio Private Ltd Compositions and methods for the treatment of diabetes and pre-diabetes
US9096537B1 (en) 2014-12-31 2015-08-04 Mahesh Kandula Compositions and methods for the treatment of mucositis
CN103910770B (zh) * 2014-03-14 2017-01-04 天津南开允公医药科技有限公司 一种托吡酯的制备方法以及该方法中所涉及的中间体晶型及其制备方法
EP3240779B1 (fr) 2014-09-26 2020-10-28 Cellixbio Private Limited Compositions et méthodes de traitement de l'épilepsie et de troubles neurologiques
ES2799309T3 (es) 2014-09-29 2020-12-16 Cellix Bio Private Ltd Compuestos y composiciones para el tratamiento de esclerosis múltiple
CA2965449C (fr) 2014-10-27 2020-11-10 Cellix Bio Private Limited Sels ternaires d'ester monomethylique d'acide fumarique associes a la piperazine ou a l'ethylenediamine pour le traitement de la sclerose en plaques
US9284287B1 (en) 2014-11-05 2016-03-15 Cellix Bio Private Limited Compositions and methods for the suppression of carbonic anhydrase activity
US9321716B1 (en) 2014-11-05 2016-04-26 Cellix Bio Private Limited Compositions and methods for the treatment of metabolic syndrome
US9290486B1 (en) 2014-11-05 2016-03-22 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy
US10208014B2 (en) 2014-11-05 2019-02-19 Cellix Bio Private Limited Compositions and methods for the treatment of neurological disorders
US9173877B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Compositions and methods for the treatment of local pain
US9175008B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Prodrugs of anti-platelet agents
US9150557B1 (en) 2014-11-05 2015-10-06 Cellix Bio Private Limited Compositions and methods for the treatment of hyperglycemia
CN107207411A (zh) 2014-12-01 2017-09-26 塞尔利克斯生物私人有限公司 用于治疗多发性硬化的组合物和方法
US9206111B1 (en) 2014-12-17 2015-12-08 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
ES2905771T3 (es) 2015-01-06 2022-04-12 Cellix Bio Private Ltd Composiciones y procedimientos para el tratamiento de la inflamación y del dolor
US20210087059A1 (en) * 2018-03-27 2021-03-25 Daikin Industries, Ltd. Production method for lithium sulfamate, and novel lithium sulfamate
CN110655542A (zh) * 2018-06-29 2020-01-07 鲁南制药集团股份有限公司 一种2,3:4,5-双-O-(1-甲基亚乙基)-β-D-吡喃果糖氯磺酸酯的晶型
CN114685526A (zh) * 2020-12-25 2022-07-01 长沙博源医疗科技有限公司 一种托吡酯衍生物、免疫原、抗托吡酯特异性抗体及其制备方法与应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
US5194446A (en) * 1989-06-12 1993-03-16 A. H. Robins Company, Incorporated Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals
US5273993A (en) * 1989-06-12 1993-12-28 A. H. Robins Company, Incorporated Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals
PT94305B (pt) 1989-06-12 1997-02-28 Robins Co Inc A H Processo para a preparacao de compostos tendo um ou mais radicais aminossulfoniloxi uteis como produtos farmaceuticos
US5192785A (en) * 1989-09-03 1993-03-09 A. H. Robins Company, Incorporated Sulfamates as antiglaucoma agents
US5025031A (en) * 1989-11-30 1991-06-18 A. H. Robins Co., Inc. Aryl and aryloxyalkyl sulfamate esters useful as anticonvulsants
AU651244B2 (en) * 1991-09-19 1994-07-14 Mcneilab, Inc. Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3:4,5-bis-0-(1-methylethylidene)-beta-D- fructopyranose and (1-methylcyclohexyl)methanol
US5242942A (en) * 1992-04-28 1993-09-07 Mcneilab, Inc. Anticonvulsant fructopyranose cyclic sulfites and sulfates
WO1995017406A1 (fr) * 1993-12-23 1995-06-29 Ortho Pharmaceutical Corporation Sulfamates de pseudofructopyranose anticonvulsifs
US5998380A (en) 1995-10-13 1999-12-07 New England Medical Center Hospitals, Inc. Treatment of migraine
US5952187A (en) 1995-12-01 1999-09-14 Oxis International, Inc. Topiramate immunoassay
JP3602906B2 (ja) * 1996-03-05 2004-12-15 富士写真フイルム株式会社 熱現像感光材料

Also Published As

Publication number Publication date
TWI281472B (en) 2007-05-21
RU2004133334A (ru) 2005-06-10
RU2328502C2 (ru) 2008-07-10
TW200404078A (en) 2004-03-16
MXPA04011232A (es) 2005-08-16
BR0309964A (pt) 2005-03-01
CN1665828A (zh) 2005-09-07
PL373910A1 (en) 2005-09-19
WO2003097656A2 (fr) 2003-11-27
US7060725B2 (en) 2006-06-13
EP1506212A2 (fr) 2005-02-16
JP2005526852A (ja) 2005-09-08
US20060058373A1 (en) 2006-03-16
WO2003097656A3 (fr) 2004-06-10
US7560459B2 (en) 2009-07-14
AU2003232112B2 (en) 2008-12-18
AU2003232112A1 (en) 2003-12-02
CN1665828B (zh) 2012-06-27
AR040412A1 (es) 2005-04-06
ZA200409989B (en) 2006-02-22
IL165108A0 (en) 2005-12-18
UA78566C2 (en) 2007-04-10
NO20045369L (no) 2004-12-08
US20040038911A1 (en) 2004-02-26
CA2485966A1 (fr) 2003-11-27
NZ537139A (en) 2008-05-30

Similar Documents

Publication Publication Date Title
MEP45308A (en) [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
MEP58808A (en) Dihydropteridinones, method for the production and use thereof in the form of drugs
EA200500342A1 (ru) Гетероциклические замещённые пиперазины для лечения шизофрении
CY1116885T1 (el) Υποκατεστημενα παραγωγα κυκλοεξυλομεθυλιου
TW200621777A (en) New dihydropteridione derivatives, process for their manufacture and their use as medicament
BRPI0411294A (pt) derivados de amino-propanol
HUP0401538A2 (hu) Új, helyettesített aminometilcsoportot tartalmazó N-(arilszulfonil)-béta-aminosav-származékok, előállításukra alkalmas eljárás és a vegyületeket tartalmazó gyógyászati készítmények
TW200621262A (en) New dihydropteridione derivatives, process for their manufacture and their use as medicament
EA200870282A1 (ru) Производные амина
NO20061406L (no) Organiske forbindelser
MEP9309A (en) Novel oligosaccharides, preparation method and pharmaceutical compositions containing the same
NO20050741L (no) Ny fremgangsmate for syntesen og ny krystallinsk form av agomelatin og farmasoytiske sammensetninger inneholdende den
DE60236600D1 (de) Substituierte 1h-dihydropyrazole, ihre herstellung und verwendung
HRP20050933A2 (en) Organic compounds
DE50310161D1 (de) Kationisch substituierte diphenylazetidinone, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
HRP20070146B1 (hr) Novi derivati fenilaminopiridina kao inhibitori bcr-abl kinaze
CL2003002565A1 (es) Compuestos derivados de 3h-quinazolin-4-ona, su proceso de preparacion, composicion farmaceutica que los contiene, y uso en el tratamiento y prevencion de enfermedades mediadas por inhibidores de mao-b, tales como la enfermedad de alzheimer y demenci
SE0300092D0 (sv) Novel compounds
EA200101234A1 (ru) Новые производные аминотиазола, их получение и содержащие их фармацевтические композиции
SE0300091D0 (sv) Novel compounds
ATE411296T1 (de) Imidazolinderivate mit cb1-antagonistischer wirkung
MY139454A (en) 4-(aminomethyl)-piperidine benzamides as 5ht4-antagonists
ATE482933T1 (de) Sulfopyrrolderivate
BR0318521A (pt) arilindenopiridinas e arilindenopirimidinas e métodos terapêuticos e profiláticos relacionados
TW200714598A (en) Urea derivatives, methods for their manufacture, and uses therefor

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ODRP Renewal fee for the maintenance of a patent

Payment date: 20090505

Year of fee payment: 7

OBST Application withdrawn