HRP20080330T3 - Antitumoral compounds based on kahalalide f - Google Patents

Antitumoral compounds based on kahalalide f

Info

Publication number
HRP20080330T3
HRP20080330T3 HR20080330T HRP20080330T HRP20080330T3 HR P20080330 T3 HRP20080330 T3 HR P20080330T3 HR 20080330 T HR20080330 T HR 20080330T HR P20080330 T HRP20080330 T HR P20080330T HR P20080330 T3 HRP20080330 T3 HR P20080330T3
Authority
HR
Croatia
Prior art keywords
kahalalide
compounds based
antitumoral compounds
formula
amino acid
Prior art date
Application number
HR20080330T
Other languages
English (en)
Croatian (hr)
Inventor
Albericio Palomera Fernando
Fernandez Donis Ariadna
Giralt Lledo Ernest
Gracia Cantador Carolina
Lopez Rodriguez Pilar
Varon Colomer Sonia
Cuevas Marchante Carmen
Lopez Macia Angel
Francesch Solloso Andr�s
Jiminez Garcia Jos�-Carlos
Royo Exposito Miriam
Original Assignee
Pharma Mar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar filed Critical Pharma Mar
Publication of HRP20080330T3 publication Critical patent/HRP20080330T3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HR20080330T 2003-09-09 2004-09-09 Antitumoral compounds based on kahalalide f HRP20080330T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0321066.3A GB0321066D0 (en) 2003-09-09 2003-09-09 New antitumoral compounds
PCT/GB2004/003847 WO2005023846A1 (en) 2003-09-09 2004-09-09 New antitumoral compounds

Publications (1)

Publication Number Publication Date
HRP20080330T3 true HRP20080330T3 (en) 2009-04-30

Family

ID=29226738

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20080330T HRP20080330T3 (en) 2003-09-09 2004-09-09 Antitumoral compounds based on kahalalide f

Country Status (23)

Country Link
US (1) US20070117743A1 (de)
EP (6) EP2280027A3 (de)
JP (4) JP4874796B2 (de)
KR (1) KR20060073618A (de)
CN (2) CN100467482C (de)
AT (1) ATE393776T1 (de)
AU (2) AU2004270471B2 (de)
CA (1) CA2537128A1 (de)
CY (1) CY1108226T1 (de)
DE (1) DE602004013454T2 (de)
DK (2) DK1664093T3 (de)
ES (2) ES2536285T3 (de)
GB (1) GB0321066D0 (de)
HR (1) HRP20080330T3 (de)
HU (1) HUE025308T2 (de)
IL (1) IL173929A (de)
MX (1) MXPA06002741A (de)
NZ (4) NZ545700A (de)
PL (1) PL1664093T3 (de)
PT (1) PT1664093E (de)
RU (2) RU2395520C2 (de)
SI (1) SI1664093T1 (de)
WO (1) WO2005023846A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0002952D0 (en) * 2000-02-09 2000-03-29 Pharma Mar Sa Process for producing kahalalide F compounds
GB0304367D0 (en) 2003-02-26 2003-04-02 Pharma Mar Sau Methods for treating psoriasis
US7507708B2 (en) 2003-02-26 2009-03-24 Pharma Mar, S.A.U. Antitumoral compounds
WO2009052379A2 (en) * 2007-10-19 2009-04-23 Pharma Mar, S.A. Improved antitumoral treatments
EP2252315A1 (de) * 2008-01-30 2010-11-24 Pharma Mar, S.A. Verbesserte antitumorale behandlungen
EP2262522A1 (de) * 2008-03-07 2010-12-22 Pharma Mar, S.A. Verbesserte antitumorale behandlungen
CN101519437B (zh) * 2009-04-09 2012-05-02 中国人民解放军第二军医大学 西沙海绵中一种环七肽类化合物及其用途
CN104725266B (zh) * 2014-04-10 2016-08-10 申俊 酰亚胺类化合物的合成方法
KR102491180B1 (ko) 2017-04-27 2023-01-20 파르마 마르 에스.에이. 항종양 화합물

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU22545A1 (es) * 1994-11-18 1999-03-31 Centro Inmunologia Molecular Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico
US4943533A (en) * 1984-03-01 1990-07-24 The Regents Of The University Of California Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor
JPS6178719A (ja) * 1984-09-25 1986-04-22 Tanabe Seiyaku Co Ltd 総合輸液剤
CA2082160C (en) * 1991-03-06 2003-05-06 Mary M. Bendig Humanised and chimeric monoclonal antibodies
GB9300059D0 (en) * 1992-01-20 1993-03-03 Zeneca Ltd Quinazoline derivatives
US6274551B1 (en) * 1994-02-03 2001-08-14 Pharmamar, S.A. Cytotoxic and antiviral compound
GB9302046D0 (en) 1993-02-03 1993-03-24 Pharma Mar Sa Antiumoral compound-v
US5705511A (en) * 1994-10-14 1998-01-06 Cephalon, Inc. Fused pyrrolocarbazoles
GB9508538D0 (en) * 1995-04-27 1995-06-14 Zeneca Ltd Quinazoline derivatives
US5747498A (en) * 1996-05-28 1998-05-05 Pfizer Inc. Alkynyl and azido-substituted 4-anilinoquinazolines
AR007857A1 (es) * 1996-07-13 1999-11-24 Glaxo Group Ltd Compuestos heterociclicos fusionados como inhibidores de proteina tirosina quinasa, sus metodos de preparacion, intermediarios uso en medicina ycomposiciones farmaceuticas que los contienen.
US6235883B1 (en) * 1997-05-05 2001-05-22 Abgenix, Inc. Human monoclonal antibodies to epidermal growth factor receptor
RS49779B (sr) * 1998-01-12 2008-06-05 Glaxo Group Limited, Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
US6200598B1 (en) * 1998-06-18 2001-03-13 Duke University Temperature-sensitive liposomal formulation
EA003786B1 (ru) * 1998-11-19 2003-10-30 Варнер Ламберт Компани N-[4-(3-хлор-4-фторфениламино)-7-(3-морфолин-4-илпропокси)хиназолин-6-ил]акриламид - необратимый ингибитор тирозинкиназ
US7311924B2 (en) * 1999-04-01 2007-12-25 Hana Biosciences, Inc. Compositions and methods for treating cancer
UA74803C2 (uk) * 1999-11-11 2006-02-15 Осі Фармасьютікалз, Інк. Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
GB0002952D0 (en) * 2000-02-09 2000-03-29 Pharma Mar Sa Process for producing kahalalide F compounds
NZ525243A (en) * 2000-10-31 2005-01-28 Pharma Mar S A lyophilised formulation comprising kahalalide F, a peptide isolated from a herbivorous marine species of mollusc, Elysia rufescens, to treat cancer
EP1435990A1 (de) * 2001-10-19 2004-07-14 Pharma Mar, S.A. Kahalalid-verbindungen zur verwendung in der krebstherapie
EP1572726B1 (de) 2002-10-18 2010-12-08 Pharma Mar, S.A.U. 4-methylhexanoic kahalalide f verbindung
GB0304367D0 (en) * 2003-02-26 2003-04-02 Pharma Mar Sau Methods for treating psoriasis
KR101149095B1 (ko) * 2002-10-18 2012-05-30 파르마 마르 에스.에이.유. 4-메틸헥사노 카할라리드 ｆ 화합물
US7507708B2 (en) * 2003-02-26 2009-03-24 Pharma Mar, S.A.U. Antitumoral compounds

Also Published As

Publication number Publication date
IL173929A0 (en) 2006-07-05
US20070117743A1 (en) 2007-05-24
NZ589890A (en) 2011-11-25
EP2280027A3 (de) 2011-05-04
EP2280026A2 (de) 2011-02-02
CY1108226T1 (el) 2014-02-12
AU2011202286B2 (en) 2013-08-01
PL1664093T3 (pl) 2008-10-31
EP1664093B1 (de) 2008-04-30
CN101531707A (zh) 2009-09-16
EP2280025A3 (de) 2011-05-25
NZ595490A (en) 2013-04-26
KR20060073618A (ko) 2006-06-28
AU2004270471A1 (en) 2005-03-17
MXPA06002741A (es) 2006-06-05
ATE393776T1 (de) 2008-05-15
ES2536285T3 (es) 2015-05-22
JP2012031187A (ja) 2012-02-16
JP5372096B2 (ja) 2013-12-18
EP2280027A2 (de) 2011-02-02
EP2664623B1 (de) 2015-03-04
RU2006111491A (ru) 2007-11-20
RU2395520C2 (ru) 2010-07-27
DK2664623T3 (en) 2015-05-11
HUE025308T2 (en) 2016-01-28
GB0321066D0 (en) 2003-10-08
CA2537128A1 (en) 2005-03-17
CN100467482C (zh) 2009-03-11
DE602004013454T2 (de) 2009-06-18
CN1849333A (zh) 2006-10-18
JP4874796B2 (ja) 2012-02-15
DK1664093T3 (da) 2008-08-18
EP2280025A2 (de) 2011-02-02
EP2280026A3 (de) 2011-05-25
JP2012051899A (ja) 2012-03-15
ES2305843T3 (es) 2008-11-01
SI1664093T1 (sl) 2008-12-31
EP1664093B8 (de) 2008-08-13
EP2664623A1 (de) 2013-11-20
EP1918296A3 (de) 2009-06-24
NZ545700A (en) 2010-03-26
PT1664093E (pt) 2008-08-07
AU2004270471B2 (en) 2011-06-02
WO2005023846A1 (en) 2005-03-17
EP1918296B1 (de) 2012-11-14
JP2007526904A (ja) 2007-09-20
EP1918296A2 (de) 2008-05-07
DE602004013454D1 (de) 2008-06-12
RU2009147217A (ru) 2011-06-27
JP2012031188A (ja) 2012-02-16
IL173929A (en) 2014-01-30
EP1664093A1 (de) 2006-06-07
NZ580124A (en) 2011-01-28
AU2011202286A1 (en) 2011-06-09

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