HRP20080330T3 - Antitumoral compounds based on kahalalide f - Google Patents

Antitumoral compounds based on kahalalide f

Info

Publication number: HRP20080330T3
Authority: HR; Croatia
Prior art keywords: kahalalide; compounds based; antitumoral compounds; formula; amino acid
Prior art date: 2003-09-09

Application number

HR20080330T

Other languages

English (en)

Croatian (hr)

Inventor

Albericio Palomera Fernando

Fernandez Donis Ariadna

Giralt Lledo Ernest

Gracia Cantador Carolina

Lopez Rodriguez Pilar

Varon Colomer Sonia

Cuevas Marchante Carmen

Lopez Macia Angel

Francesch Solloso Andr�s

Jiminez Garcia Jos�-Carlos

Royo Exposito Miriam

Original Assignee

Pharma Mar

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-09-09

Filing date

2004-09-09

Publication date

2009-04-30

2004-09-09 Application filed by Pharma Mar filed Critical Pharma Mar

2009-04-30 Publication of HRP20080330T3 publication Critical patent/HRP20080330T3/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Virology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

HR20080330T 2003-09-09 2004-09-09 Antitumoral compounds based on kahalalide f HRP20080330T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0321066.3A GB0321066D0 (en)	2003-09-09	2003-09-09	New antitumoral compounds
PCT/GB2004/003847 WO2005023846A1 (fr)	2003-09-09	2004-09-09	Nouveaux composes anti-tumoraux

Publications (1)

Publication Number	Publication Date
HRP20080330T3 true HRP20080330T3 (en)	2009-04-30

Family

ID=29226738

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20080330T HRP20080330T3 (en)	2003-09-09	2004-09-09	Antitumoral compounds based on kahalalide f

Country Status (23)

Country	Link
US (1)	US20070117743A1 (fr)
EP (6)	EP2280026A3 (fr)
JP (4)	JP4874796B2 (fr)
KR (1)	KR20060073618A (fr)
CN (2)	CN100467482C (fr)
AT (1)	ATE393776T1 (fr)
AU (2)	AU2004270471B2 (fr)
CA (1)	CA2537128A1 (fr)
CY (1)	CY1108226T1 (fr)
DE (1)	DE602004013454T2 (fr)
DK (2)	DK1664093T3 (fr)
ES (2)	ES2536285T3 (fr)
GB (1)	GB0321066D0 (fr)
HR (1)	HRP20080330T3 (fr)
HU (1)	HUE025308T2 (fr)
IL (1)	IL173929A (fr)
MX (1)	MXPA06002741A (fr)
NZ (4)	NZ595490A (fr)
PL (1)	PL1664093T3 (fr)
PT (1)	PT1664093E (fr)
RU (2)	RU2395520C2 (fr)
SI (1)	SI1664093T1 (fr)
WO (1)	WO2005023846A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0002952D0 (en) *	2000-02-09	2000-03-29	Pharma Mar Sa	Process for producing kahalalide F compounds
GB0304367D0 (en)	2003-02-26	2003-04-02	Pharma Mar Sau	Methods for treating psoriasis
US7507708B2 (en)	2003-02-26	2009-03-24	Pharma Mar, S.A.U.	Antitumoral compounds
WO2009052379A2 (fr) *	2007-10-19	2009-04-23	Pharma Mar, S.A.	Traitements antitumoraux améliorés
AU2009209541A1 (en) *	2008-01-30	2009-08-06	Pharma Mar, S.A.	Improved antitumoral treatments
CN101965192A (zh) *	2008-03-07	2011-02-02	法马马有限公司	改善的抗肿瘤治疗
CN101519437B (zh) *	2009-04-09	2012-05-02	中国人民解放军第二军医大学	西沙海绵中一种环七肽类化合物及其用途
CN104725266B (zh) *	2014-04-10	2016-08-10	申俊	酰亚胺类化合物的合成方法
US11332480B2 (en)	2017-04-27	2022-05-17	Pharma Mar, S.A.	Antitumoral compounds

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CU22545A1 (es) *	1994-11-18	1999-03-31	Centro Inmunologia Molecular	Obtención de un anticuerpo quimérico y humanizado contra el receptor del factor de crecimiento epidérmico para uso diagnóstico y terapéutico
US4943533A (en) *	1984-03-01	1990-07-24	The Regents Of The University Of California	Hybrid cell lines that produce monoclonal antibodies to epidermal growth factor receptor
JPS6178719A (ja) *	1984-09-25	1986-04-22	Tanabe Seiyaku Co Ltd	総合輸液剤
SK281143B6 (sk) *	1991-03-06	2000-12-11	Merck Patent Gesellschaft Mit Beschr�Nkter Haftung	Chimérická monoklonálna protilátka, expresné vektory a farmaceutický prostriedok
GB9300059D0 (en) *	1992-01-20	1993-03-03	Zeneca Ltd	Quinazoline derivatives
GB9302046D0 (en)	1993-02-03	1993-03-24	Pharma Mar Sa	Antiumoral compound-v
US6274551B1 (en) *	1994-02-03	2001-08-14	Pharmamar, S.A.	Cytotoxic and antiviral compound
US5705511A (en) *	1994-10-14	1998-01-06	Cephalon, Inc.	Fused pyrrolocarbazoles
GB9508538D0 (en) *	1995-04-27	1995-06-14	Zeneca Ltd	Quinazoline derivatives
US5747498A (en) *	1996-05-28	1998-05-05	Pfizer Inc.	Alkynyl and azido-substituted 4-anilinoquinazolines
DE69716916T2 (de) *	1996-07-13	2003-07-03	Glaxo Group Ltd., Greenford	Kondensierte heterozyklische verbindungen als protein kinase inhibitoren
US6235883B1 (en) *	1997-05-05	2001-05-22	Abgenix, Inc.	Human monoclonal antibodies to epidermal growth factor receptor
RS49779B (sr) *	1998-01-12	2008-06-05	Glaxo Group Limited,	Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze
US6200598B1 (en) *	1998-06-18	2001-03-13	Duke University	Temperature-sensitive liposomal formulation
ES2188254T3 (es) *	1998-11-19	2003-06-16	Warner Lambert Co	N-(4-(3-chloro-4-fluoro-fenilamino)-7-(3-morfolin-4-il-propoxi)-quin azolin-6-il)-acrilamada, un inhibidor irreversible de tirosina quinasas.
US7311924B2 (en) *	1999-04-01	2007-12-25	Hana Biosciences, Inc.	Compositions and methods for treating cancer
UA74803C2 (uk) *	1999-11-11	2006-02-15	Осі Фармасьютікалз, Інк.	Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
GB0002952D0 (en)	2000-02-09	2000-03-29	Pharma Mar Sa	Process for producing kahalalide F compounds
HUP0600031A3 (en)	2000-10-31	2012-02-28	Pharma Mar	Kahalalide formulations and their use
CA2462639A1 (fr) *	2001-10-19	2003-04-24	Pharma Mar, S.A.	Composes a base de kahalalide utilisables en therapie anticancereuse
GB0304367D0 (en) *	2003-02-26	2003-04-02	Pharma Mar Sau	Methods for treating psoriasis
PT1572726E (pt) *	2002-10-18	2011-02-14	Pharma Mar Sau	Composto kahalalide f 4-metil-hexanóico
EP1572726B1 (fr)	2002-10-18	2010-12-08	Pharma Mar, S.A.U.	Composes 4-methylhexanoic kahalalide f
US7507708B2 (en) *	2003-02-26	2009-03-24	Pharma Mar, S.A.U.	Antitumoral compounds

2003
- 2003-09-09 GB GBGB0321066.3A patent/GB0321066D0/en not_active Ceased
2004
- 2004-09-09 JP JP2006525886A patent/JP4874796B2/ja not_active Expired - Fee Related
- 2004-09-09 SI SI200430765T patent/SI1664093T1/sl unknown
- 2004-09-09 PT PT04768394T patent/PT1664093E/pt unknown
- 2004-09-09 ES ES13180582.2T patent/ES2536285T3/es not_active Expired - Lifetime
- 2004-09-09 US US10/570,734 patent/US20070117743A1/en not_active Abandoned
- 2004-09-09 CA CA002537128A patent/CA2537128A1/fr not_active Abandoned
- 2004-09-09 MX MXPA06002741A patent/MXPA06002741A/es active IP Right Grant
- 2004-09-09 HR HR20080330T patent/HRP20080330T3/xx unknown
- 2004-09-09 NZ NZ595490A patent/NZ595490A/xx not_active IP Right Cessation
- 2004-09-09 DK DK04768394T patent/DK1664093T3/da active
- 2004-09-09 EP EP10179442A patent/EP2280026A3/fr not_active Withdrawn
- 2004-09-09 WO PCT/GB2004/003847 patent/WO2005023846A1/fr not_active Ceased
- 2004-09-09 AT AT04768394T patent/ATE393776T1/de active
- 2004-09-09 EP EP08100973A patent/EP1918296B1/fr not_active Expired - Lifetime
- 2004-09-09 AU AU2004270471A patent/AU2004270471B2/en not_active Ceased
- 2004-09-09 EP EP04768394A patent/EP1664093B8/fr not_active Expired - Lifetime
- 2004-09-09 PL PL04768394T patent/PL1664093T3/pl unknown
- 2004-09-09 ES ES04768394T patent/ES2305843T3/es not_active Expired - Lifetime
- 2004-09-09 CN CNB2004800258906A patent/CN100467482C/zh not_active Expired - Fee Related
- 2004-09-09 NZ NZ589890A patent/NZ589890A/en not_active IP Right Cessation
- 2004-09-09 KR KR1020067004786A patent/KR20060073618A/ko not_active Abandoned
- 2004-09-09 RU RU2006111491/04A patent/RU2395520C2/ru not_active IP Right Cessation
- 2004-09-09 EP EP10179425A patent/EP2280025A3/fr not_active Withdrawn
- 2004-09-09 EP EP13180582.2A patent/EP2664623B1/fr not_active Expired - Lifetime
- 2004-09-09 EP EP10179452A patent/EP2280027A3/fr not_active Withdrawn
- 2004-09-09 HU HUE13180582A patent/HUE025308T2/en unknown
- 2004-09-09 DE DE602004013454T patent/DE602004013454T2/de not_active Expired - Lifetime
- 2004-09-09 NZ NZ580124A patent/NZ580124A/en not_active IP Right Cessation
- 2004-09-09 NZ NZ545700A patent/NZ545700A/en not_active IP Right Cessation
- 2004-09-09 CN CN200910001891A patent/CN101531707A/zh active Pending
- 2004-09-09 DK DK13180582.2T patent/DK2664623T3/en active
2006
- 2006-02-26 IL IL173929A patent/IL173929A/en not_active IP Right Cessation
2008
- 2008-07-30 CY CY20081100794T patent/CY1108226T1/el unknown
2009
- 2009-12-18 RU RU2009147217/04A patent/RU2009147217A/ru not_active Application Discontinuation
2011
- 2011-05-17 AU AU2011202286A patent/AU2011202286B2/en not_active Ceased
- 2011-09-29 JP JP2011214680A patent/JP2012051899A/ja active Pending
- 2011-09-29 JP JP2011214681A patent/JP2012031187A/ja active Pending
- 2011-09-29 JP JP2011214682A patent/JP5372096B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
EP1664093A1 (fr)	2006-06-07
ATE393776T1 (de)	2008-05-15
NZ595490A (en)	2013-04-26
JP2012031187A (ja)	2012-02-16
DE602004013454D1 (de)	2008-06-12
JP5372096B2 (ja)	2013-12-18
EP2280027A2 (fr)	2011-02-02
EP2280026A3 (fr)	2011-05-25
KR20060073618A (ko)	2006-06-28
AU2004270471A1 (en)	2005-03-17
AU2011202286B2 (en)	2013-08-01
JP4874796B2 (ja)	2012-02-15
ES2536285T3 (es)	2015-05-22
CN1849333A (zh)	2006-10-18
EP2280025A3 (fr)	2011-05-25
HUE025308T2 (en)	2016-01-28
RU2395520C2 (ru)	2010-07-27
NZ589890A (en)	2011-11-25
JP2007526904A (ja)	2007-09-20
CA2537128A1 (fr)	2005-03-17
PT1664093E (pt)	2008-08-07
US20070117743A1 (en)	2007-05-24
EP2280025A2 (fr)	2011-02-02
EP1918296A3 (fr)	2009-06-24
JP2012051899A (ja)	2012-03-15
WO2005023846A1 (fr)	2005-03-17
PL1664093T3 (pl)	2008-10-31
DK1664093T3 (da)	2008-08-18
CN100467482C (zh)	2009-03-11
GB0321066D0 (en)	2003-10-08
CY1108226T1 (el)	2014-02-12
EP1664093B8 (fr)	2008-08-13
DK2664623T3 (en)	2015-05-11
NZ580124A (en)	2011-01-28
AU2011202286A1 (en)	2011-06-09
ES2305843T3 (es)	2008-11-01
IL173929A0 (en)	2006-07-05
MXPA06002741A (es)	2006-06-05
RU2009147217A (ru)	2011-06-27
CN101531707A (zh)	2009-09-16
EP1918296B1 (fr)	2012-11-14
EP1918296A2 (fr)	2008-05-07
EP2280027A3 (fr)	2011-05-04
NZ545700A (en)	2010-03-26
RU2006111491A (ru)	2007-11-20
JP2012031188A (ja)	2012-02-16
SI1664093T1 (sl)	2008-12-31
EP2664623B1 (fr)	2015-03-04
IL173929A (en)	2014-01-30
EP2664623A1 (fr)	2013-11-20
EP2280026A2 (fr)	2011-02-02
EP1664093B1 (fr)	2008-04-30
AU2004270471B2 (en)	2011-06-02
DE602004013454T2 (de)	2009-06-18

Publication	Publication Date	Title
EA200300050A1 (ru)	2003-04-24	Гликопептидфосфонатные производные
HRP20090195T1 (hr)	2009-05-31	Inhibitori mitotičkih kinezina
EA200200938A1 (ru)	2003-02-27	Фармацевтические композиции, содержащие производные азетидина, новые производные азетидина и их получение
HRP20040317A2 (en)	2006-06-30	1,8-naphthyridine derivatives as antidiabetics
HRP20120323T1 (en)	2012-05-31	Diarylhydantoin compounds
HRP20090281T1 (hr)	2009-06-30	1,2,3,4-tetrasubstituirani indol za liječenje respiratornih bolesti
EA200500814A1 (ru)	2006-02-24	Производные пирролопиримидина
HRP20030383B1 (hr)	2007-12-31	Laktamski spoj
EE200100485A (et)	2003-02-17	Uudsed ühendid ja kompositsioonid proteaasi inhibiitoritena
NO20034291D0 (no)	2003-09-25	2-aminopropanolderivater
DE602004008098D1 (de)	2007-09-20	Substituierte 2h-ä1,2,4ütriazoloä4,3-aüpyrazine als gsk-3-inhibitoren
AP2002002637A0 (en)	2002-09-30	Novel piperazine
CR8107A (es)	2006-07-27	Fungicida
MX2007012090A (es)	2007-11-21	Derivados sustituidos de pirazoliloxifenilo como herbicidas.
BR0211972A (pt)	2004-09-21	Composição oftálmica
DK1483246T3 (da)	2006-04-10	5-Substituerede alkylaminopyrazolderivater som pesticider
PA8573501A1 (es)	2003-12-10	Derivados de benzoxazina y su empleo
HRP20090152T3 (en)	2009-05-31	Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses thereof
HRP20090474T1 (hr)	2009-10-31	Postupak i intermedijeri za sintezu kaspofungina
EA200300392A1 (ru)	2003-10-30	Производные пиперазина с мостиковой связью
YU44301A (sh)	2004-07-15	5ht1 antagonisti za antidepresantnu terapiju
HRP20070286T3 (en)	2007-08-31	Substituted diketopiperazines and their use as oxytocyn antagonists
BRPI0411664A (pt)	2006-08-08	composição oral antiplaca aquosa estável
EA200201232A1 (ru)	2003-04-24	Производные сульфонамида
HUP9601526A2 (hu)	1998-10-28	Véralvadásgátló hatású peptidil-arginin-aldehid-származékok és a vegyületeket tartalmazó gyógyszerkészítmények