HRP20090061T3 - Purine derivatives acting as a2a receptor agonists - Google Patents

Purine derivatives acting as a2a receptor agonists

Info

Publication number: HRP20090061T3
Authority: HR; Croatia
Prior art keywords: alkyl; amino; optionally substituted; aryl; group
Prior art date: 2005-01-14

Application number

HR20090061T

Other languages

English (en)

Croatian (hr)

Inventor

Alec Fairhurst Robin

John Taylor Roger

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-01-14

Filing date

2006-01-12

Publication date

2009-03-31

2006-01-12 Application filed by Novartis Ag filed Critical Novartis Ag

2009-03-31 Publication of HRP20090061T3 publication Critical patent/HRP20090061T3/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Diabetes (AREA)
Physical Education & Sports Medicine (AREA)
Ophthalmology & Optometry (AREA)
Neurology (AREA)
Hematology (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Obesity (AREA)
Immunology (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

HR20090061T 2005-01-14 2006-01-12 Purine derivatives acting as a2a receptor agonists HRP20090061T3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0500785.1A GB0500785D0 (en)	2005-01-14	2005-01-14	Organic compounds
PCT/EP2006/000217 WO2006074925A1 (fr)	2005-01-14	2006-01-12	Derives puriniques agissant comme des agonistes du recepteur a2a

Publications (1)

Publication Number	Publication Date
HRP20090061T3 true HRP20090061T3 (en)	2009-03-31

Family

ID=34224620

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20090061T HRP20090061T3 (en)	2005-01-14	2006-01-12	Purine derivatives acting as a2a receptor agonists

Country Status (31)

Country	Link
US (1)	US8114877B2 (fr)
EP (1)	EP1841768B1 (fr)
JP (1)	JP2008526911A (fr)
KR (1)	KR20070093424A (fr)
CN (1)	CN101107249B (fr)
AR (1)	AR052659A1 (fr)
AT (1)	ATE414085T1 (fr)
AU (1)	AU2006205878B2 (fr)
BR (1)	BRPI0606324A2 (fr)
CA (1)	CA2593398A1 (fr)
CY (1)	CY1108752T1 (fr)
DE (1)	DE602006003628D1 (fr)
DK (1)	DK1841768T3 (fr)
ES (1)	ES2317483T3 (fr)
GB (1)	GB0500785D0 (fr)
GT (1)	GT200600013A (fr)
HR (1)	HRP20090061T3 (fr)
IL (1)	IL184149A0 (fr)
MA (1)	MA29170B1 (fr)
MX (1)	MX2007008557A (fr)
MY (1)	MY141727A (fr)
NO (1)	NO20074050L (fr)
PE (1)	PE20060833A1 (fr)
PL (1)	PL1841768T3 (fr)
PT (1)	PT1841768E (fr)
RU (1)	RU2400483C2 (fr)
SI (1)	SI1841768T1 (fr)
TN (1)	TNSN07268A1 (fr)
TW (1)	TW200637863A (fr)
WO (1)	WO2006074925A1 (fr)
ZA (1)	ZA200704743B (fr)

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GB0505219D0 (en) *	2005-03-14	2005-04-20	Novartis Ag	Organic compounds
GB0607953D0 (en) *	2006-04-21	2006-05-31	Novartis Ag	Organic compounds
GB0607948D0 (en) *	2006-04-21	2006-05-31	Novartis Ag	Organic compounds
GB0607954D0 (en) *	2006-04-21	2006-05-31	Novartis Ag	Organic compounds
GB0607951D0 (en) *	2006-04-21	2006-05-31	Novartis Ag	Organic compounds
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GB0607950D0 (en) *	2006-04-21	2006-05-31	Novartis Ag	Organic compounds
GB0607945D0 (en) *	2006-04-21	2006-05-31	Novartis Ag	Organic compounds
GB0607944D0 (en) *	2006-04-21	2006-05-31	Novartis Ag	Organic compounds
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GB0500785D0 (en)	2005-01-14	2005-02-23	Novartis Ag	Organic compounds
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2005
- 2005-01-14 GB GBGB0500785.1A patent/GB0500785D0/en not_active Ceased
2006
- 2006-01-06 MY MYPI20060048A patent/MY141727A/en unknown
- 2006-01-11 GT GT200600013A patent/GT200600013A/es unknown
- 2006-01-12 CA CA002593398A patent/CA2593398A1/fr not_active Abandoned
- 2006-01-12 PT PT06700452T patent/PT1841768E/pt unknown
- 2006-01-12 US US11/722,835 patent/US8114877B2/en not_active Expired - Fee Related
- 2006-01-12 PL PL06700452T patent/PL1841768T3/pl unknown
- 2006-01-12 HR HR20090061T patent/HRP20090061T3/xx unknown
- 2006-01-12 EP EP06700452A patent/EP1841768B1/fr not_active Expired - Lifetime
- 2006-01-12 RU RU2007130802/04A patent/RU2400483C2/ru not_active IP Right Cessation
- 2006-01-12 DE DE602006003628T patent/DE602006003628D1/de not_active Expired - Lifetime
- 2006-01-12 AR ARP060100129A patent/AR052659A1/es not_active Application Discontinuation
- 2006-01-12 ES ES06700452T patent/ES2317483T3/es not_active Expired - Lifetime
- 2006-01-12 MX MX2007008557A patent/MX2007008557A/es active IP Right Grant
- 2006-01-12 SI SI200630194T patent/SI1841768T1/sl unknown
- 2006-01-12 DK DK06700452T patent/DK1841768T3/da active
- 2006-01-12 CN CN2006800024512A patent/CN101107249B/zh not_active Expired - Fee Related
- 2006-01-12 BR BRPI0606324-1A patent/BRPI0606324A2/pt not_active IP Right Cessation
- 2006-01-12 AT AT06700452T patent/ATE414085T1/de active
- 2006-01-12 JP JP2007550752A patent/JP2008526911A/ja active Pending
- 2006-01-12 WO PCT/EP2006/000217 patent/WO2006074925A1/fr not_active Ceased
- 2006-01-12 AU AU2006205878A patent/AU2006205878B2/en not_active Ceased
- 2006-01-12 KR KR1020077016098A patent/KR20070093424A/ko not_active Ceased
- 2006-01-13 TW TW095101304A patent/TW200637863A/zh unknown
- 2006-01-13 PE PE2006000062A patent/PE20060833A1/es not_active Application Discontinuation
2007
- 2007-06-20 ZA ZA200704743A patent/ZA200704743B/xx unknown
- 2007-06-21 IL IL184149A patent/IL184149A0/en unknown
- 2007-07-13 TN TNP2007000268A patent/TNSN07268A1/en unknown
- 2007-07-26 MA MA30103A patent/MA29170B1/fr unknown
- 2007-08-06 NO NO20074050A patent/NO20074050L/no not_active Application Discontinuation
2009
- 2009-02-05 CY CY20091100134T patent/CY1108752T1/el unknown

Also Published As

Publication number	Publication date
ZA200704743B (en)	2008-08-27
CY1108752T1 (el)	2014-04-09
CA2593398A1 (fr)	2006-07-20
SI1841768T1 (sl)	2009-04-30
DK1841768T3 (da)	2009-03-02
NO20074050L (no)	2007-09-17
MY141727A (en)	2010-06-15
CN101107249A (zh)	2008-01-16
GB0500785D0 (en)	2005-02-23
WO2006074925A1 (fr)	2006-07-20
TNSN07268A1 (en)	2008-12-31
ATE414085T1 (de)	2008-11-15
PE20060833A1 (es)	2006-10-13
AR052659A1 (es)	2007-03-28
EP1841768A1 (fr)	2007-10-10
DE602006003628D1 (de)	2008-12-24
AU2006205878B2 (en)	2009-10-22
EP1841768B1 (fr)	2008-11-12
CN101107249B (zh)	2010-10-13
US8114877B2 (en)	2012-02-14
GT200600013A (es)	2006-08-02
PT1841768E (pt)	2009-02-05
TW200637863A (en)	2006-11-01
AU2006205878A1 (en)	2006-07-20
MA29170B1 (fr)	2008-01-02
ES2317483T3 (es)	2009-04-16
IL184149A0 (en)	2007-10-31
MX2007008557A (es)	2007-08-14
US20080207648A1 (en)	2008-08-28
KR20070093424A (ko)	2007-09-18
HK1112458A1 (en)	2008-09-05
BRPI0606324A2 (pt)	2009-06-16
RU2400483C2 (ru)	2010-09-27
PL1841768T3 (pl)	2009-04-30
JP2008526911A (ja)	2008-07-24
RU2007130802A (ru)	2009-02-20

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