HRP920384B1 - A process for the preparation of albuterol, acetal, hemi-acetal and hydrates of arylglyoxal intermediates thereof - Google Patents

A process for the preparation of albuterol, acetal, hemi-acetal and hydrates of arylglyoxal intermediates thereof

Info

Publication number: HRP920384B1
Authority: HR; Croatia
Prior art keywords: acetal; hemi; preparation; intermediates; albuterol
Prior art date: 1990-09-11

Application number

HRP-1498/91A

Other languages

English (en)

Inventor

Junning Lee

Original Assignee

Junning Lee

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-11

Filing date

1992-09-21

Publication date

1998-10-31

1992-09-21 Application filed by Junning Lee filed Critical Junning Lee

1995-10-31 Publication of HRP920384A2 publication Critical patent/HRP920384A2/hr

1998-10-31 Publication of HRP920384B1 publication Critical patent/HRP920384B1/xx

Links

NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 title abstract 3
229960002052 salbutamol Drugs 0.000 title abstract 3
DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 title abstract 2
150000001241 acetals Chemical class 0.000 title abstract 2
150000002373 hemiacetals Chemical class 0.000 title abstract 2
239000000543 intermediate Substances 0.000 title abstract 2
150000004677 hydrates Chemical class 0.000 title 1
ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 1
229910052796 boron Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/56—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups
- C07C215/58—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
- C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/022—Boron compounds without C-boron linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

HRP-1498/91A 1990-09-11 1992-09-21 A process for the preparation of albuterol, acetal, hemi-acetal and hydrates of arylglyoxal intermediates thereof HRP920384B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US58070590A	1990-09-11	1990-09-11
YU149891A YU48672B (sh)	1990-09-11	1991-09-09	Bor-ariletanolamin kompleks, acetali i hemi acetali i postupak za dobivanje ariletanolamina, acetala, hemiacetala i hidrata arilglioksal intermedijera

Publications (2)

Publication Number	Publication Date
HRP920384A2 HRP920384A2 (en)	1995-10-31
HRP920384B1 true HRP920384B1 (en)	1998-10-31

Family

ID=24322195

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HRP-1498/91A HRP920384B1 (en)	1990-09-11	1992-09-21	A process for the preparation of albuterol, acetal, hemi-acetal and hydrates of arylglyoxal intermediates thereof

Country Status (24)

Country	Link
US (1)	US5283359A (pt)
EP (1)	EP0548224B1 (pt)
JP (2)	JP3055757B2 (pt)
KR (1)	KR960006670B1 (pt)
CN (1)	CN1051759C (pt)
AT (1)	ATE114300T1 (pt)
AU (2)	AU648114B2 (pt)
CA (2)	CA2091352C (pt)
DE (2)	DE69105277T2 (pt)
DK (1)	DK0548224T3 (pt)
ES (1)	ES2059288T3 (pt)
GR (1)	GR930300087T1 (pt)
HR (1)	HRP920384B1 (pt)
HU (1)	HUT65809A (pt)
IE (1)	IE66041B1 (pt)
IL (6)	IL99436A (pt)
MX (1)	MX9101019A (pt)
NZ (2)	NZ248939A (pt)
PT (1)	PT98906B (pt)
SI (1)	SI9111498A (pt)
TW (1)	TW363955B (pt)
WO (1)	WO1992004314A2 (pt)
YU (1)	YU48672B (pt)
ZA (1)	ZA917150B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5442118A (en) *	1994-04-22	1995-08-15	Sepracor, Inc.	Asymmetric synthesis of (R)- and (S)-arylethanolamines from iminoketones
US5545745A (en) *	1994-05-23	1996-08-13	Sepracor, Inc.	Enantioselective preparation of optically pure albuterol
US5399765A (en) *	1994-05-23	1995-03-21	Sepracor, Inc.	Enantioselective preparation of optically pure albuterol
EP1648855A2 (en)	2004-05-20	2006-04-26	Teva Pharmaceutical Fine Chemicals S.R.L.	Levalbuterol hydrochloride polymorph a
US8070045B1 (en) *	2010-12-02	2011-12-06	Rohm And Haas Electronic Materials Llc	Curable amine flux composition and method of soldering
US8070044B1 (en) *	2010-12-02	2011-12-06	Rohm And Haas Electronic Materials Llc	Polyamine flux composition and method of soldering
WO2016082862A1 (de)	2014-11-25	2016-06-02	Dometic S.A.R.L.	Kühlvorrichtung
CN105001100A (zh) *	2015-06-11	2015-10-28	山西云鹏制药有限公司	一种精制硫酸沙丁胺醇的方法
CN109072171A (zh)	2016-05-12	2018-12-21	三得利控股株式会社	含有l-羟脯氨酸的解脂耶氏酵母的菌体或菌体培养物或者它们的提取物及其用途以及l-羟脯氨酸的制造方法
CN106748824A (zh) *	2016-11-21	2017-05-31	河南工业大学	一种新的沙丁胺醇药物盐‑沙丁胺醇富马酸盐及其制备方法
CN108863819B (zh) *	2018-06-26	2021-01-15	南京逐陆医药科技有限公司	一种游离的消旋沙丁胺醇的制备方法
CN110734382B (zh) *	2019-10-09	2024-02-20	苏州弘森药业股份有限公司	一种合成特布他林的方法
CN112341373B (zh) *	2020-11-30	2022-04-08	山东嘉成医药科技有限公司	一种酞丁安的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1200886A (en) *	1966-09-23	1970-08-05	Allen & Hanburys Ltd	Phenylaminoethanol derivatives
GB1214012A (en) *	1967-12-21	1970-11-25	Allen & Hanburys Ltd	Phenylethanolamines
GB1247370A (en) *	1968-12-31	1971-09-22	Allen & Hanburys Ltd	Glyoxals and production thereof
GB1266058A (pt) *	1969-07-08	1972-03-08
US4029706A (en) *	1974-04-01	1977-06-14	Dynapol	Reduction with polymeric reagent
US3928293A (en) *	1974-04-01	1975-12-23	Dynapol Corp	Polymeric reagent
DE2730462A1 (de) *	1976-07-15	1978-01-19	Ciba Geigy Ag	Photoinitiatoren fuer uv-haertbare massen
EP0114389A3 (en) *	1983-01-20	1985-12-18	American Cyanamid Company	Substituted arylglyoxal derivatives
WO1988010253A1 (en) *	1987-06-24	1988-12-29	Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt.	Process for the preparation of quinoline carboxylic acid derivatives

1991
- 1991-09-06 IL IL9943691A patent/IL99436A/en not_active IP Right Cessation
- 1991-09-06 CA CA002091352A patent/CA2091352C/en not_active Expired - Fee Related
- 1991-09-06 DE DE69105277T patent/DE69105277T2/de not_active Expired - Fee Related
- 1991-09-06 WO PCT/US1991/006248 patent/WO1992004314A2/en not_active Ceased
- 1991-09-06 CA CA002121914A patent/CA2121914C/en not_active Expired - Fee Related
- 1991-09-06 JP JP6303806A patent/JP3055757B2/ja not_active Expired - Lifetime
- 1991-09-06 US US08/030,185 patent/US5283359A/en not_active Expired - Fee Related
- 1991-09-06 KR KR1019930700720A patent/KR960006670B1/ko not_active Expired - Fee Related
- 1991-09-06 AT AT91916922T patent/ATE114300T1/de not_active IP Right Cessation
- 1991-09-06 JP JP3515879A patent/JPH07113006B2/ja not_active Expired - Lifetime
- 1991-09-06 IL IL11947691A patent/IL119476A/xx not_active IP Right Cessation
- 1991-09-06 EP EP91916922A patent/EP0548224B1/en not_active Expired - Lifetime
- 1991-09-06 AU AU86170/91A patent/AU648114B2/en not_active Ceased
- 1991-09-06 DE DE91916922T patent/DE548224T1/de active Pending
- 1991-09-06 HU HU9300684A patent/HUT65809A/hu unknown
- 1991-09-06 ES ES91916922T patent/ES2059288T3/es not_active Expired - Lifetime
- 1991-09-06 DK DK91916922.7T patent/DK0548224T3/da active
- 1991-09-06 IL IL11947791A patent/IL119477A/xx not_active IP Right Cessation
- 1991-09-09 PT PT98906A patent/PT98906B/pt not_active IP Right Cessation
- 1991-09-09 TW TW080107103A patent/TW363955B/zh active
- 1991-09-09 ZA ZA917150A patent/ZA917150B/xx unknown
- 1991-09-09 YU YU149891A patent/YU48672B/sh unknown
- 1991-09-09 SI SI9111498A patent/SI9111498A/sl unknown
- 1991-09-10 IE IE317491A patent/IE66041B1/en not_active IP Right Cessation
- 1991-09-10 CN CN91108911A patent/CN1051759C/zh not_active Expired - Fee Related
- 1991-09-10 MX MX9101019A patent/MX9101019A/es not_active IP Right Cessation
- 1991-09-10 NZ NZ248939A patent/NZ248939A/en unknown
- 1991-09-10 NZ NZ239732A patent/NZ239732A/en unknown
1992
- 1992-09-21 HR HRP-1498/91A patent/HRP920384B1/xx not_active IP Right Cessation
1993
- 1993-09-30 GR GR930300087T patent/GR930300087T1/el unknown
1994
- 1994-02-10 AU AU55086/94A patent/AU656287B2/en not_active Ceased
1995
- 1995-10-19 IL IL115678A patent/IL115678A/en not_active IP Right Cessation
1996
- 1996-10-23 IL IL11947696A patent/IL119476A0/xx unknown
- 1996-10-23 IL IL11947796A patent/IL119477A0/xx unknown

Also Published As

Publication number	Publication date
IL119476A0 (en)	1997-01-10
EP0548224A1 (en)	1993-06-30
NZ248939A (en)	1995-03-28
DE69105277D1 (de)	1995-01-05
IL115678A0 (en)	1996-01-19
IE66041B1 (en)	1995-12-13
CA2091352A1 (en)	1992-03-12
US5283359A (en)	1994-02-01
PT98906A (pt)	1992-09-30
MX9101019A (es)	1992-05-04
JPH05506668A (ja)	1993-09-30
HRP920384A2 (en)	1995-10-31
CN1051759C (zh)	2000-04-26
ES2059288T3 (es)	1995-01-16
HUT65809A (en)	1994-07-28
HU9300684D0 (en)	1993-06-28
NZ239732A (en)	1995-03-28
CN1059904A (zh)	1992-04-01
AU648114B2 (en)	1994-04-14
YU48672B (sh)	1999-06-15
DK0548224T3 (da)	1995-01-09
IL119476A (en)	1999-10-28
AU8617091A (en)	1992-03-30
CA2121914A1 (en)	1992-03-12
ES2059288T1 (es)	1994-11-16
ATE114300T1 (de)	1994-12-15
IL99436A (en)	1999-03-12
IL99436A0 (en)	1992-08-18
CA2121914C (en)	1998-09-29
KR960006670B1 (ko)	1996-05-22
IL119477A0 (en)	1997-01-10
JPH07233115A (ja)	1995-09-05
CA2091352C (en)	1996-12-03
YU149891A (sh)	1994-01-20
AU5508694A (en)	1994-04-28
PT98906B (pt)	1999-02-26
JP3055757B2 (ja)	2000-06-26
IE913174A1 (en)	1992-03-11
WO1992004314A2 (en)	1992-03-19
EP0548224B1 (en)	1994-11-23
SI9111498A (en)	1997-12-31
DE548224T1 (de)	1993-10-14
DE69105277T2 (de)	1995-04-06
JPH07113006B2 (ja)	1995-12-06
ZA917150B (en)	1992-05-27
GR930300087T1 (en)	1993-09-30
WO1992004314A3 (en)	1992-05-29
IL119477A (en)	1999-10-28
TW363955B (en)	1999-07-11
IL115678A (en)	1998-01-04
AU656287B2 (en)	1995-01-27

Legal Events

Date	Code	Title	Description
1995-10-31	A1OB	Publication of a patent application
1996-04-23	AIPI	Request for the grant of a patent on the basis of a substantive examination of a patent application
1998-10-31	B1PR	Patent granted
2000-09-09	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20000909 Year of fee payment: 10
2002-03-10	PBON	Lapse due to non-payment of renewal fee	Effective date: 20010910

Publication	Publication Date	Title
IL99436A0 (en)	1992-08-18	Process for preparing albuterol,acetal,hemi-acetal,and hydrates of arylglyoxal intermediates thereof
SI0810981T1 (en)	2002-04-30	Method for manufacturing a mineral wool product
SI0960109T1 (en)	2003-04-30	Process to prepare tolterodine
UA18261A (uk)	1997-12-25	Спосіб одержаhhя простих перфторполіефірів
ATE112239T1 (de)	1994-10-15	Vaterit und verfahren zu dessen herstellung.
GR3021155T3 (en)	1996-12-31	Sustained release alginate fibre and process for the preparation thereof.
ES2131528T3 (es)	1999-08-01	Nuevos polipeptidos y su uso.
GR930300084T1 (en)	1993-09-30	Intermediates for chelating agents with prefixed symmetry and process for their preparation.
IT1244886B (it)	1994-09-13	Dicarbonati e uretani dell'acido 4,5-diidrossi- e 4,5,8-triidrossi- 9,10-diidro-9,10-diosso-2-antracencarbossilico ad azione terapeutica
GR3024343T3 (en)	1997-10-31	A process for the preparation of 9-(2-hydroxy)-ethoxymethyl-guanine
HU9204126D0 (en)	1993-04-28	Method and device for producing beta-caseine
ZA894824B (en)	1990-07-25	New material based on boron nitride,its process of preparation and its use as a reinforcing agent
GR3023270T3 (en)	1997-07-30	Process for coating the internal surface of hydrothermosanitary pipes, particularly made of aluminium, with resinous products and pipes obtained therewith.
EP0429993A3 (en)	1991-09-25	Method of forming thin film containing boron nitride, magnetic head and method of preparing said magnetic head
GB9414303D0 (en)	1994-09-07	Alginate fibres, method of preparation and use
GR3032992T3 (en)	2000-07-31	Cyclohexanone derivatives, method of preparing them and intermediates used in the method
AU6686394A (en)	1994-12-12	Preparation of fluoro-nucleosides and intermediates for use therein
FR2696757B1 (fr)	1994-12-09	Composition d'aciers à outils.
TW327175B (en)	1998-02-21	Process for preparing steroidal 3,5-diene-3-carboxylic acid derivatives
AU5160593A (en)	1994-04-26	Process for producing a spectacle side piece, and side piece according to such process
沈谦	1992	The Artistic Form of Leaves Grass
HU9203784D0 (en)	1993-03-29	Method fo rproducing cubic boron nitride based composite material of high hardness