HU187414B - Process for producing cough-preparation of physiologically relieving and sedative effect, fixable on skin - Google Patents

Process for producing cough-preparation of physiologically relieving and sedative effect, fixable on skin Download PDF

Info

Publication number: HU187414B
Authority: HU; Hungary
Prior art keywords: skin; priority; carrier; cough; composition according
Prior art date: 1984-10-12

Application number

HU823048A

Other languages

German (de)

English (en)

Hungarian (hu)

Inventor

Gaspar Leopold

Attila Sziklai

Original Assignee

Leopold,Gaspar,Hu

Sziklai,Attila,Hu

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-12

Filing date

1984-10-12

Publication date

1986-01-28

1984-10-12 Application filed by Leopold,Gaspar,Hu, Sziklai,Attila,Hu filed Critical Leopold,Gaspar,Hu

1984-10-12 Priority to HU823048A priority Critical patent/HU187414B/hu

1985-10-11 Priority to EP85905100A priority patent/EP0198003A1/en

1985-10-11 Priority to PCT/HU1985/000060 priority patent/WO1986002270A1/en

1985-10-11 Priority to DD85281661A priority patent/DD243642A5/de

1986-01-28 Publication of HU187414B publication Critical patent/HU187414B/hu

1986-06-12 Priority to DK277486A priority patent/DK277486A/da

Links

206010011224 Cough Diseases 0.000 title claims abstract description 14
238000002360 preparation method Methods 0.000 title claims abstract description 6
238000000034 method Methods 0.000 title claims abstract description 4
230000001624 sedative effect Effects 0.000 title description 2
239000000203 mixture Substances 0.000 claims abstract description 33
239000010642 eucalyptus oil Substances 0.000 claims abstract description 12
229940044949 eucalyptus oil Drugs 0.000 claims abstract description 12
235000003351 Brassica cretica Nutrition 0.000 claims abstract description 10
235000003343 Brassica rupestris Nutrition 0.000 claims abstract description 10
QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 claims abstract description 10
235000010460 mustard Nutrition 0.000 claims abstract description 10
244000056139 Brassica cretica Species 0.000 claims abstract 2
229920000915 polyvinyl chloride Polymers 0.000 claims description 8
239000004800 polyvinyl chloride Substances 0.000 claims description 8
239000003963 antioxidant agent Substances 0.000 claims description 6
230000003078 antioxidant effect Effects 0.000 claims description 6
239000011241 protective layer Substances 0.000 claims description 5
NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical group CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 4
238000009472 formulation Methods 0.000 claims description 4
239000000758 substrate Substances 0.000 claims description 4
230000001914 calming effect Effects 0.000 claims description 2
239000011810 insulating material Substances 0.000 claims description 2
239000012876 carrier material Substances 0.000 claims 1
239000002985 plastic film Substances 0.000 claims 1
229920006255 plastic film Polymers 0.000 claims 1
239000004480 active ingredient Substances 0.000 abstract description 6
230000000954 anitussive effect Effects 0.000 abstract description 6
235000015277 pork Nutrition 0.000 abstract description 4
239000008194 pharmaceutical composition Substances 0.000 abstract description 2
238000013268 sustained release Methods 0.000 abstract description 2
239000012730 sustained-release form Substances 0.000 abstract description 2
238000004519 manufacturing process Methods 0.000 abstract 2
230000002195 synergetic effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 description 17
241000219198 Brassica Species 0.000 description 8
239000000853 adhesive Substances 0.000 description 8
230000001070 adhesive effect Effects 0.000 description 8
206010006451 bronchitis Diseases 0.000 description 7
208000006673 asthma Diseases 0.000 description 6
239000000463 material Substances 0.000 description 6
229940124584 antitussives Drugs 0.000 description 5
239000004744 fabric Substances 0.000 description 5
ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 description 4
239000003814 drug Substances 0.000 description 4
210000002706 plastid Anatomy 0.000 description 4
MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 4
239000004698 Polyethylene Substances 0.000 description 3
230000003247 decreasing effect Effects 0.000 description 3
229940079593 drug Drugs 0.000 description 3
239000011888 foil Substances 0.000 description 3
-1 polyethylene Polymers 0.000 description 3
229920000573 polyethylene Polymers 0.000 description 3
230000002829 reductive effect Effects 0.000 description 3
239000000341 volatile oil Substances 0.000 description 3
206010011225 Cough decreased Diseases 0.000 description 2
208000000059 Dyspnea Diseases 0.000 description 2
206010013975 Dyspnoeas Diseases 0.000 description 2
239000005844 Thymol Substances 0.000 description 2
238000004026 adhesive bonding Methods 0.000 description 2
230000002411 adverse Effects 0.000 description 2
229930013930 alkaloid Natural products 0.000 description 2
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
229910052782 aluminium Inorganic materials 0.000 description 2
OROGSEYTTFOCAN-DNJOTXNNSA-N codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 description 2
235000013305 food Nutrition 0.000 description 2
239000012051 hydrophobic carrier Substances 0.000 description 2
229920003023 plastic Polymers 0.000 description 2
239000004033 plastic Substances 0.000 description 2
239000000126 substance Substances 0.000 description 2
239000004753 textile Substances 0.000 description 2
229960000790 thymol Drugs 0.000 description 2
NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 description 1
WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 1
206010006458 Bronchitis chronic Diseases 0.000 description 1
201000004813 Bronchopneumonia Diseases 0.000 description 1
241000723346 Cinnamomum camphora Species 0.000 description 1
NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
206010067482 No adverse event Diseases 0.000 description 1
240000004760 Pimpinella anisum Species 0.000 description 1
235000012550 Pimpinella anisum Nutrition 0.000 description 1
206010035737 Pneumonia viral Diseases 0.000 description 1
206010044314 Tracheobronchitis Diseases 0.000 description 1
206010056397 Tracheomalacia Diseases 0.000 description 1
ZOJBYZNEUISWFT-UHFFFAOYSA-N allyl isothiocyanate Chemical compound C=CCN=C=S ZOJBYZNEUISWFT-UHFFFAOYSA-N 0.000 description 1
239000003434 antitussive agent Substances 0.000 description 1
229960004217 benzyl alcohol Drugs 0.000 description 1
230000002146 bilateral effect Effects 0.000 description 1
210000000621 bronchi Anatomy 0.000 description 1
229960000846 camphor Drugs 0.000 description 1
229930008380 camphor Natural products 0.000 description 1
208000007451 chronic bronchitis Diseases 0.000 description 1
210000004081 cilia Anatomy 0.000 description 1
229960004126 codeine Drugs 0.000 description 1
230000000052 comparative effect Effects 0.000 description 1
238000001816 cooling Methods 0.000 description 1
230000018044 dehydration Effects 0.000 description 1
238000006297 dehydration reaction Methods 0.000 description 1
238000003745 diagnosis Methods 0.000 description 1
235000014113 dietary fatty acids Nutrition 0.000 description 1
230000003292 diminished effect Effects 0.000 description 1
239000002019 doping agent Substances 0.000 description 1
230000008030 elimination Effects 0.000 description 1
238000003379 elimination reaction Methods 0.000 description 1
238000001704 evaporation Methods 0.000 description 1
230000008020 evaporation Effects 0.000 description 1
239000003172 expectorant agent Substances 0.000 description 1
230000003419 expectorant effect Effects 0.000 description 1
229930195729 fatty acid Natural products 0.000 description 1
239000000194 fatty acid Substances 0.000 description 1
150000004665 fatty acids Chemical class 0.000 description 1
229940124600 folk medicine Drugs 0.000 description 1
OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 description 1
230000002209 hydrophobic effect Effects 0.000 description 1
208000030603 inherited susceptibility to asthma Diseases 0.000 description 1
238000009413 insulation Methods 0.000 description 1
229940041616 menthol Drugs 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
230000002906 microbiologic effect Effects 0.000 description 1
230000036651 mood Effects 0.000 description 1
239000008164 mustard oil Substances 0.000 description 1
231100000957 no side effect Toxicity 0.000 description 1
RGOVYLWUIBMPGK-UHFFFAOYSA-N nonivamide Chemical compound CCCCCCCCC(=O)NCC1=CC=C(O)C(OC)=C1 RGOVYLWUIBMPGK-UHFFFAOYSA-N 0.000 description 1
231100000252 nontoxic Toxicity 0.000 description 1
229940066366 other cough suppressants in atc Drugs 0.000 description 1
230000035515 penetration Effects 0.000 description 1
208000008423 pleurisy Diseases 0.000 description 1
230000002035 prolonged effect Effects 0.000 description 1
150000003180 prostaglandins Chemical class 0.000 description 1
239000000932 sedative agent Substances 0.000 description 1
208000013220 shortness of breath Diseases 0.000 description 1
230000001954 sterilising effect Effects 0.000 description 1
238000004659 sterilization and disinfection Methods 0.000 description 1
230000001629 suppression Effects 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
231100000331 toxic Toxicity 0.000 description 1
230000002588 toxic effect Effects 0.000 description 1
150000003626 triacylglycerols Chemical class 0.000 description 1
208000011479 upper respiratory tract disease Diseases 0.000 description 1
208000009421 viral pneumonia Diseases 0.000 description 1
230000003612 virological effect Effects 0.000 description 1
230000036642 wellbeing Effects 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Natural Medicines & Medicinal Plants (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Botany (AREA)
Biotechnology (AREA)
Dermatology (AREA)
Medical Informatics (AREA)
Microbiology (AREA)
Mycology (AREA)
Alternative & Traditional Medicine (AREA)
Zoology (AREA)
Hematology (AREA)
Materials Engineering (AREA)
Pulmonology (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Preparation (AREA)
Medicines Containing Plant Substances (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

HU823048A 1984-10-12 1984-10-12 Process for producing cough-preparation of physiologically relieving and sedative effect, fixable on skin HU187414B (en)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
HU823048A HU187414B (en)	1984-10-12	1984-10-12	Process for producing cough-preparation of physiologically relieving and sedative effect, fixable on skin
EP85905100A EP0198003A1 (en)	1984-10-12	1985-10-11	Cough-relieving compositions
PCT/HU1985/000060 WO1986002270A1 (en)	1984-10-12	1985-10-11	Cough-relieving compositions
DD85281661A DD243642A5 (de)	1984-10-12	1985-10-11	Hustenlinderungsmittel
DK277486A DK277486A (da)	1984-10-12	1986-06-12	Cough-relieving compositions

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU823048A HU187414B (en)	1984-10-12	1984-10-12	Process for producing cough-preparation of physiologically relieving and sedative effect, fixable on skin

Publications (1)

Publication Number	Publication Date
HU187414B true HU187414B (en)	1986-01-28

Family

ID=10962279

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU823048A HU187414B (en)	1984-10-12	1984-10-12	Process for producing cough-preparation of physiologically relieving and sedative effect, fixable on skin

Country Status (5)

Country	Link
EP (1)	EP0198003A1 (da)
DD (1)	DD243642A5 (da)
DK (1)	DK277486A (da)
HU (1)	HU187414B (da)
WO (1)	WO1986002270A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4433191A1 (de) *	1994-09-17	1996-03-21	Lohmann Therapie Syst Lts	Selbstklebendes Pflaster zur Abgabe von Wirkstoff an die Umgebung eines Trägers
RU2125855C1 (ru) *	1996-10-08	1999-02-10	Открытое акционерное общество Волгоградский маслоэкстракционный завод "Сарепта"	Горчичник
IN183330B (da) *	1998-03-23	1999-11-20	Dalmia Ct For Biotechnology
AU2000250055A1 (en) *	2000-04-13	2001-10-30	Lectec Corporation	Therapeutic patch containing a liquid or gel organic compound as a carrier
US20040071757A1 (en) *	2001-11-20	2004-04-15	David Rolf	Inhalation antiviral patch
CN104971322A (zh) *	2015-06-11	2015-10-14	钟兴欢	一种黄皮清咽润喉片

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB190719133A (en) *	1907-08-26	1908-05-07	William Bryant	An Improved Ointment
AT261811B (de) *	1963-11-18	1968-05-10	Sophie Lintner	Verfahren zur Herstellung einer homogenen Salbe

1984
- 1984-10-12 HU HU823048A patent/HU187414B/hu not_active IP Right Cessation
1985
- 1985-10-11 DD DD85281661A patent/DD243642A5/de not_active IP Right Cessation
- 1985-10-11 EP EP85905100A patent/EP0198003A1/en not_active Withdrawn
- 1985-10-11 WO PCT/HU1985/000060 patent/WO1986002270A1/en not_active Ceased
1986
- 1986-06-12 DK DK277486A patent/DK277486A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO1986002270A1 (en)	1986-04-24
EP0198003A1 (en)	1986-10-22
DD243642A5 (de)	1987-03-11
DK277486D0 (da)	1986-06-12
DK277486A (da)	1986-07-28

Legal Events

Date	Code	Title	Description
1990-06-28	HU90	Patent valid on 900628
1990-09-28	HPC4	Succession in title of patentee	Owner name: KPS ELEKTRONIKAI GYARTO- SZOLGALTATO ES KERESKEDEL
1990-09-28	HQB4	Licence granted & registered	Free format text: KPS ELEKTRONIKAI GYARTO- SZOLGALTATO ES KERESKEDELMI KFT (HU)
1994-06-28	HMM4	Cancellation of final prot. due to non-payment of fee

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