HU198736B - Process for producing 16-dehydro-20-oxopregnane derivatives - Google Patents

Process for producing 16-dehydro-20-oxopregnane derivatives Download PDF

Info

Publication number: HU198736B
Authority: HU; Hungary
Prior art keywords: oxo; acid; dinor; dehydro; process according
Prior art date: 1986-12-29

Application number

HU549986A

Other languages

English (en)

Hungarian (hu)

Other versions

HUT46035A (en

Inventor

Andras Toro

Nandor Makk

Lajos Toldy

Sarudy Eva Toth

Gyula Horvath

Antalne Jekkel

Karoly Albrecht

Gabor Ambrus

Tibor Lang

Eva Ilkoey

Original Assignee

Gyogyszerkutato Intezet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-29

Filing date

1986-12-29

Publication date

1989-11-28

1986-12-29 Application filed by Gyogyszerkutato Intezet filed Critical Gyogyszerkutato Intezet

1986-12-29 Priority to HU549986A priority Critical patent/HU198736B/hu

1987-12-29 Priority to NL8703151A priority patent/NL8703151A/nl

1987-12-29 Priority to GB8730269A priority patent/GB2199325B/en

1988-01-04 Priority to JP4788A priority patent/JPH0830076B2/ja

1988-09-28 Publication of HUT46035A publication Critical patent/HUT46035A/hu

1989-11-28 Publication of HU198736B publication Critical patent/HU198736B/hu

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Catalysts (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

HU549986A 1986-12-29 1986-12-29 Process for producing 16-dehydro-20-oxopregnane derivatives HU198736B (en)

Priority Applications (4)

Application Number	Priority Date	Filing Date	Title
HU549986A HU198736B (en)	1986-12-29	1986-12-29	Process for producing 16-dehydro-20-oxopregnane derivatives
NL8703151A NL8703151A (nl)	1986-12-29	1987-12-29	Werkwijze voor de bereiding van 16-dehydro-20-oxopregnanderivaten.
GB8730269A GB2199325B (en)	1986-12-29	1987-12-29	Process for preparing 16-dehydro-20-oxopregnane derivatives and such derivatives
JP4788A JPH0830076B2 (ja)	1986-12-29	1988-01-04	１６−デヒドロ−２０−オキソプレグナン誘導体，及びその製造方法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU549986A HU198736B (en)	1986-12-29	1986-12-29	Process for producing 16-dehydro-20-oxopregnane derivatives

Publications (2)

Publication Number	Publication Date
HUT46035A HUT46035A (en)	1988-09-28
HU198736B true HU198736B (en)	1989-11-28

Family

ID=10970368

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU549986A HU198736B (en)	1986-12-29	1986-12-29	Process for producing 16-dehydro-20-oxopregnane derivatives

Country Status (4)

Country	Link
JP (1)	JPH0830076B2 (ja)
GB (1)	GB2199325B (ja)
HU (1)	HU198736B (ja)
NL (1)	NL8703151A (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2720747B1 (fr) *	1994-06-02	1996-07-12	Roussel Uclaf	Nouveau procédé de préparation d'un stéroïde 16béta-méthyl et nouveaux intermédiaires.
WO2005110958A1 (ja)	2004-05-14	2005-11-24	Shionogi & Co., Ltd.	過酸化水素およびタングステン触媒を用いたアルコールの酸化反応
CN1907998B (zh) *	2005-08-05	2010-05-26	天津天药药业股份有限公司	地塞米松系列产品中间体21-甲基四烯物的精制工艺方法
CN105622700B (zh) *	2016-01-29	2017-12-22	山东赛托生物科技股份有限公司	一种甾体中间体甲基四烯物的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2966511D1 (en) *	1978-07-31	1984-02-02	Upjohn Co	Epoxypregnadienes, hydroxypregnatrienes, process for their preparation and process for their conversion to precursors of useful anti-inflammatory agents
US4189430A (en) *	1978-07-31	1980-02-19	The Upjohn Company	Epoxide process

1986
- 1986-12-29 HU HU549986A patent/HU198736B/hu not_active IP Right Cessation
1987
- 1987-12-29 NL NL8703151A patent/NL8703151A/nl not_active Application Discontinuation
- 1987-12-29 GB GB8730269A patent/GB2199325B/en not_active Expired - Lifetime
1988
- 1988-01-04 JP JP4788A patent/JPH0830076B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NL8703151A (nl)	1988-07-18
GB2199325A (en)	1988-07-06
HUT46035A (en)	1988-09-28
JPS63190898A (ja)	1988-08-08
GB8730269D0 (en)	1988-02-03
GB2199325B (en)	1990-04-25
JPH0830076B2 (ja)	1996-03-27

Legal Events

Date	Code	Title	Description
1990-06-28	HU90	Patent valid on 900628
1992-03-30	HPC4	Succession in title of patentee	Owner name: RICHTER GEDEON VEGYESZETI GYAR RT., HU
1997-08-28	HMM4	Cancellation of final prot. due to non-payment of fee

Publication	Publication Date	Title
HU227112B1 (hu)	2010-07-28	Ipari eljárás 17-alfa-acetoxi-11-béta-[4-(N,N-dimetil-amino)-fenil]-19-norpregna-4,9-dién-3,20-dion elõállítására és új intermedierek az eljáráshoz
US4075233A (en)	1978-02-21	16-Dehydro steroids of the androstane series
HU208437B (en)	1993-10-28	Process for producing 9-alpha-hydroxy- -17-methylene-steroides for synthetizing corticosteroides
US5093502A (en)	1992-03-03	14α,17α-dihydroxy-17β-substituted steroids
JP2643943B2 (ja)	1997-08-25	新規な６−もしくは７−メチレンアンドロスタ−１，４−ジエン−３，１７−ジオン誘導体およびその製造方法
PL187083B1 (pl)	2004-05-31	Steroidy z grupą 17-spirometylenolaktonową lub laktolową, sposób ich wytwarzania i środek farmaceutyczny
HU182607B (en)	1984-02-28	Process for preparing pregnane-21-aldehydes
JP2677626B2 (ja)	1997-11-17	１７−置換アンドロスタ−１，４−ジエン−３−オン誘導体
US6768014B2 (en)	2004-07-27	PROCESS FOR PREPARING 17α-ACETOXY-11β-[4-N,N(DIMETHYLAMINO)PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIENE-3,20-DIONE, INTERMEDIATES USEFUL IN THE PROCESS , AND PROCESSES FOR PREPARING SUCH INTERMEDIATES
JP4971179B2 (ja)	2012-07-11	１７−ヒドロキシ−６β，７β；１５β，１６β−ビスメチレン−３−オキソ−１７α−プレグネ−４−エン−２１−カルボン酸γ−ラクトンの工業的製造方法およびこの方法のための重要中間体
FR2569408A1 (fr)	1986-02-28	Nouveaux steroides substitues en position 10 par un radical comportant une double ou triple liaison, leur procede de preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant
HU198736B (en)	1989-11-28	Process for producing 16-dehydro-20-oxopregnane derivatives
JPS62158300A (ja)	1987-07-14	１０β−アルキニルエストレン誘導体およびそれらの製造法
US4548749A (en)	1985-10-22	Process for the preparation of 21-hydroxy-20-keto-Δ16 -steroids and new intermediate compounds formed in this process
HU203769B (en)	1991-09-30	Process for producing new steroide derivatives and pharmaceutical compositions containing them
US4011316A (en)	1977-03-08	Cyclohexa-2,5-diene-1-thiones
EP0286578A1 (de)	1988-10-12	4,15-Disubstituierte 4-Androsten-3,17-dione und Verfahren zu deren Herstellung
HU197924B (en)	1989-06-28	Process for producing new steroids containing sulfinyl group in the 23-position
US3954980A (en)	1976-05-04	Chemical compounds
US4220588A (en)	1980-09-02	Chemical processes
EP0071178B1 (en)	1985-10-16	Acyloxysteroids and process for producing same
HU183086B (en)	1984-04-28	Process for forming hydroxy-acetyl side chain of pregnane-type steroides
EP0040355B1 (de)	1984-07-25	Verfahren zur partiellen Reduktion von C21-Steroidcarbonsäuren und ihren Estern zu C21-Steroidalkoholen
HU187382B (en)	1985-12-28	Process for producing 17-beta-ethnyl-steroides
US3539599A (en)	1970-11-10	6,7-methylene-9beta,10alpha-steroids and methods for the preparation thereof