HUE036985T2 - Biokatalizátor és eljárások triptamin és triptamin-analógok származékainak szintetizálására - Google Patents

Biokatalizátor és eljárások triptamin és triptamin-analógok származékainak szintetizálására

Info

Publication number
HUE036985T2
HUE036985T2 HUE13765270A HUE13765270A HUE036985T2 HU E036985 T2 HUE036985 T2 HU E036985T2 HU E13765270 A HUE13765270 A HU E13765270A HU E13765270 A HUE13765270 A HU E13765270A HU E036985 T2 HUE036985 T2 HU E036985T2
Authority
HU
Hungary
Prior art keywords
tryptamine
biocatalyst
methods
analogues
synthesizing derivatives
Prior art date
Application number
HUE13765270A
Other languages
English (en)
Inventor
Jovana Nazor
Derek Smith
Michael Crowe
Shiwei Song
Steven Collier
Original Assignee
Codexis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc filed Critical Codexis Inc
Publication of HUE036985T2 publication Critical patent/HUE036985T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y206/00—Transferases transferring nitrogenous groups (2.6)
    • C12Y206/01—Transaminases (2.6.1)
    • C12Y206/01018—Beta-alanine-pyruvate transaminase (2.6.1.18)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HUE13765270A 2012-03-23 2013-03-22 Biokatalizátor és eljárások triptamin és triptamin-analógok származékainak szintetizálására HUE036985T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261614666P 2012-03-23 2012-03-23

Publications (1)

Publication Number Publication Date
HUE036985T2 true HUE036985T2 (hu) 2018-08-28

Family

ID=49223365

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE13765270A HUE036985T2 (hu) 2012-03-23 2013-03-22 Biokatalizátor és eljárások triptamin és triptamin-analógok származékainak szintetizálására

Country Status (7)

Country Link
US (7) US9139821B2 (hu)
EP (1) EP2828385B1 (hu)
CN (1) CN104508126B (hu)
DK (1) DK2828385T3 (hu)
HU (1) HUE036985T2 (hu)
SG (1) SG11201405990PA (hu)
WO (1) WO2013142770A1 (hu)

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HUE036985T2 (hu) 2012-03-23 2018-08-28 Codexis Inc Biokatalizátor és eljárások triptamin és triptamin-analógok származékainak szintetizálására
WO2014099730A1 (en) 2012-12-21 2014-06-26 Codexis, Inc. Engineered biocatalysts and methods for synthesizing chiral amines
KR102785474B1 (ko) 2014-12-18 2025-03-26 에프. 호프만-라 로슈 아게 테트라하이드로-피리도[3,4-b]인돌 에스트로겐 수용체 조절제 및 이의 용도
CN111032682B (zh) * 2017-06-14 2024-04-12 科德克希思公司 用于工业生物催化的工程化转氨酶多肽
LT3810283T (lt) 2018-06-21 2023-08-25 F. Hoffmann-La Roche Ag 3-((1r,3r)-1-(2,6-difluor-4-((1-(3-fluorpropil)azetidin-3- il)amino) fenil)-3-metil-1,3,4,9-tetrahidro-2h-pirido[3,4-b]indol-2-il)- 2,2- difluorpropan-1-olio tartrato druskos kietosios formos, jų paruošimo procesas ir jų naudojimo būdai vėžiui gydyti
CN115427557A (zh) * 2020-04-10 2022-12-02 科德克希思公司 工程化转氨酶多肽
AU2021268204A1 (en) 2020-05-08 2022-12-08 Psilera Inc. Novel compositions of matter and pharmaceutical compositions
KR20240096817A (ko) 2020-05-19 2024-06-26 사이빈 아이알엘 리미티드 중수소화된 트립타민 유도체 및 사용 방법
IL301146A (en) * 2020-09-28 2023-05-01 Codexis Inc Engineered biocatalysts and methods for synthesizing chiral amines
CN112346465B (zh) * 2020-11-27 2022-09-02 哈尔滨工程大学 基于ialos导引律的欠驱无人船自适应模糊控制方法
IL308816A (en) * 2021-05-25 2024-01-01 Atai Therapeutics Inc New n,n-dimethyltryptamine salts and crystalline salt forms
MX2023014620A (es) 2021-06-09 2024-01-30 Atai Therapeutics Inc Nuevos profarmacos y conjugados de dimetiltriptamina.
JP2024545787A (ja) 2021-12-30 2024-12-11 アタイ セラピューティクス， インコーポレイテッド 一酸化窒素送達剤としてのジメチルトリプタミン類似体

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US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
WO1995033836A1 (en) 1994-06-03 1995-12-14 Novo Nordisk Biotech, Inc. Phosphonyldipeptides useful in the treatment of cardiovascular diseases
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
FI104465B (fi) 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
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KR100718817B1 (ko) * 2004-07-19 2007-05-17 김병기 신규한 오메가아미노트랜스퍼라제, 이의 유전자 및 이의이용 방법
KR20070017562A (ko) * 2007-01-17 2007-02-12 김병기 신규한 오메가아미노트랜스퍼라제, 이의 유전자 및 이의이용 방법
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KR101694572B1 (ko) * 2009-07-24 2017-01-09 디에스엠 아이피 어셋츠 비.브이. Ｎ-아실 또는 ｎ-구아니딜 보호된 1,4-뷰테인다이아민 전구체를 통한 1,4-뷰테인다이아민의 제조 방법
DK2582799T3 (en) 2010-06-17 2018-02-12 Codexis Inc BIOCATALATORS AND PROCEDURES FOR THE SYNTHESIS OF (S) -3- (1-AMINOETHYL) -PHENOL
HUE036985T2 (hu) 2012-03-23 2018-08-28 Codexis Inc Biokatalizátor és eljárások triptamin és triptamin-analógok származékainak szintetizálására
KR101479718B1 (ko) * 2012-07-06 2015-01-08 연세대학교 산학협력단 오메가 트랜스아미나아제의 조기질 순환을 이용한 광학 활성 아미노산의 제조방법
WO2014099730A1 (en) * 2012-12-21 2014-06-26 Codexis, Inc. Engineered biocatalysts and methods for synthesizing chiral amines

Also Published As

Publication number Publication date
US20260055382A1 (en) 2026-02-26
US9708588B2 (en) 2017-07-18
DK2828385T3 (en) 2018-03-12
EP2828385A4 (en) 2015-09-16
US9139821B2 (en) 2015-09-22
EP2828385A1 (en) 2015-01-28
US20150072383A1 (en) 2015-03-12
US20160289649A1 (en) 2016-10-06
CN104508126A (zh) 2015-04-08
WO2013142770A1 (en) 2013-09-26
SG11201405990PA (en) 2014-11-27
US20210348139A1 (en) 2021-11-11
US12378537B2 (en) 2025-08-05
CN104508126B (zh) 2017-06-30
US20170283781A1 (en) 2017-10-05
EP2828385B1 (en) 2018-02-07
US9388395B2 (en) 2016-07-12
US10544402B2 (en) 2020-01-28
US20200123512A1 (en) 2020-04-23
US20150344854A1 (en) 2015-12-03
US11098291B2 (en) 2021-08-24

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