HUE037491T2 - A semi-solid aqueous formulation containing tapentadol - Google Patents

A semi-solid aqueous formulation containing tapentadol

Info

Publication number
HUE037491T2
HUE037491T2 HUE12710026A HUE12710026A HUE037491T2 HU E037491 T2 HUE037491 T2 HU E037491T2 HU E12710026 A HUE12710026 A HU E12710026A HU E12710026 A HUE12710026 A HU E12710026A HU E037491 T2 HUE037491 T2 HU E037491T2
Authority
HU
Hungary
Prior art keywords
semi
formulation containing
aqueous formulation
solid aqueous
containing tapentadol
Prior art date
Application number
HUE12710026A
Other languages
Hungarian (hu)
Inventor
Ulrich Reinhold
Marc Schiller
Eva Wulsten
Sabine Inghelbrecht
Roger EMBRECHTS
Ulrich Feil
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of HUE037491T2 publication Critical patent/HUE037491T2/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
HUE12710026A 2011-03-04 2012-03-02 A semi-solid aqueous formulation containing tapentadol HUE037491T2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161449329P 2011-03-04 2011-03-04
EP11003603 2011-05-03

Publications (1)

Publication Number Publication Date
HUE037491T2 true HUE037491T2 (en) 2018-09-28

Family

ID=44652117

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE12710026A HUE037491T2 (en) 2011-03-04 2012-03-02 A semi-solid aqueous formulation containing tapentadol

Country Status (24)

Country Link
US (3) US9446008B2 (en)
EP (3) EP3290029B1 (en)
JP (3) JP6027549B2 (en)
KR (2) KR101911362B1 (en)
CN (1) CN103501774A (en)
AU (2) AU2012224954C1 (en)
BR (1) BR112013022556A8 (en)
CA (1) CA2828637C (en)
CY (1) CY1119725T1 (en)
DK (1) DK2680834T3 (en)
EA (2) EA033171B1 (en)
ES (2) ES2910085T3 (en)
HR (1) HRP20171836T1 (en)
HU (1) HUE037491T2 (en)
IL (2) IL227826B (en)
LT (1) LT2680834T (en)
MX (2) MX344473B (en)
NO (1) NO2680834T3 (en)
PL (1) PL2680834T3 (en)
PT (2) PT3766489T (en)
RS (1) RS56692B1 (en)
SI (1) SI2680834T1 (en)
WO (1) WO2012119729A1 (en)
ZA (1) ZA201306480B (en)

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ES2910085T3 (en) * 2011-03-04 2022-05-11 Gruenenthal Gmbh Semisolid aqueous pharmaceutical composition containing tapentadol
MX388963B (en) 2011-03-04 2025-03-20 Gruenenthal Gmbh Aqueous pharmaceutical formulation of tapentadol for oral administration
US9395306B2 (en) 2011-08-05 2016-07-19 Halliburton Energy Services, Inc. Methods for monitoring fluids within or produced from a subterranean formation during acidizing operations using opticoanalytical devices
US8997860B2 (en) 2011-08-05 2015-04-07 Halliburton Energy Services, Inc. Methods for monitoring the formation and transport of a fracturing fluid using opticoanalytical devices
US8619256B1 (en) 2012-09-14 2013-12-31 Halliburton Energy Services, Inc. Systems and methods for monitoring the properties of a fluid cement composition in a flow path
US20140076550A1 (en) 2012-09-14 2014-03-20 Halliburton Energy Services, Inc. Systems and Methods for Detecting Microannulus Formation and Remediation
US9228940B2 (en) 2012-09-14 2016-01-05 Halliburton Energy Services, Inc. Systems, methods, and apparatuses for in situ monitoring of cement fluid compositions and setting processes thereof
EP3027214A1 (en) * 2013-08-02 2016-06-08 ratiopharm GmbH Composition comprising tapentadol in a dissolved form
EP2845625A1 (en) 2013-09-04 2015-03-11 Grünenthal GmbH Tapentadol for use in the treatment of fibromyalgia and chronic fatigue syndrome
PE20171651A1 (en) 2015-03-27 2017-11-13 Gruenenthal Chemie STABLE FORMULATION FOR PARENTERAL ADMINISTRATION OF TAPENTADOL
EP3515412B1 (en) 2016-09-23 2025-04-23 Grünenthal GmbH Stable formulation for parenteral administration of tapentadol
JP2021532112A (en) * 2018-07-24 2021-11-25 ドクトア・アウグスト・ボルフ・ゲーエムベーハー・ウント・コンパニー・カー・ゲー−アルツナイミツテル Topical emulsion of anticholinergic compounds
BR112021004199A2 (en) 2018-09-07 2021-05-25 R.P. Scherer Technologies, Llc stabilization of solid or semi-solid lipid-based dosage forms through curing and addition of low hlb surfactant(s)
JP7646560B2 (en) 2019-03-18 2025-03-17 サンスター アメリカス インク Oral Care Compositions

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DE4426245A1 (en) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-phenyl-3-dimethylamino-propane compounds with pharmacological activity
US6183758B1 (en) * 1998-01-29 2001-02-06 Highland Laboratories, Inc. Phytochemicals, nutrients & medication absorption &/or treatment
US6399087B1 (en) 2000-12-20 2002-06-04 Amphastar Pharmaceuticals, Inc. Propofol formulation with enhanced microbial inhibition
DE10109763A1 (en) 2001-02-28 2002-09-05 Gruenenthal Gmbh Pharmaceutical salts
US20050176790A1 (en) 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
PE20030527A1 (en) 2001-10-24 2003-07-26 Gruenenthal Chemie DELAYED-RELEASE PHARMACEUTICAL FORMULATION CONTAINING 3- (3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL) PHENOL OR A PHARMACEUTICALLY ACCEPTABLE SALT OF THE SAME AND ORAL TABLETS CONTAINING IT
CA2479350A1 (en) 2002-03-15 2003-09-25 Cypress Bioscience, Inc. Ne and 5-ht reuptake inhibitors for treating visceral pain syndromes
US20030191187A1 (en) 2002-04-01 2003-10-09 Lee Fang Yu Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same
RU2359698C2 (en) 2002-09-13 2009-06-27 Сайдекс, Инк. Capsules containing water filling compositions, stabilised with derivative of cyclodextrin
US20040180915A1 (en) 2003-03-14 2004-09-16 Xanodyne Pharmacal, Inc. Methadone-containing compositions for parenteral administration and method of use thereof
US20060111382A1 (en) 2004-05-17 2006-05-25 Pharmacofore, Inc. Compositions and methods for treating or preventing pain
PT1612203E (en) 2004-06-28 2007-08-20 Gruenenthal Gmbh Crystalline forms of (-)-(1r,2r)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride
BRPI0513300B1 (en) 2004-07-01 2018-11-06 Gruenenthal Gmbh oral dosage form, protected from abuse, containing (1r, 2r) -3- (3-dimethylamino-1-ethyl-2-methyl-lpropyl) -phenol
EP1893190A4 (en) 2005-04-28 2010-07-28 Theraquest Biosciences Llc Methods and compositions for treating pain
TWI329334B (en) 2005-12-02 2010-08-21 Chung Shan Inst Of Science Manufacture method of electromagnetic interference layer for the plasma display panel
WO2007127158A2 (en) * 2006-04-25 2007-11-08 Croda, Inc Modification of percutaneous absorption of topically active materials
ATE502629T1 (en) * 2006-04-28 2011-04-15 Gruenenthal Gmbh PHARMACEUTICAL COMBINATION WITH 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL) PHENOL AND AN NSAID
PL2012764T3 (en) 2006-04-28 2011-04-29 Gruenenthal Gmbh Pharmaceutical combination comprising 3-(3-dimethylamino-1-ethyl-2-methyl-propyl) -phenol and paracetamol
BRPI0714671B8 (en) 2006-07-24 2023-03-21 Janssen Pharmaceutica Nv PREPARATION OF (2R,3R)-3-(3-METHOXYPHENYL)-N,N,2-TRIMETHYLPENTANAMINE AND INTERMEDIATE COMPOUNDS
DE102007012165A1 (en) 2007-03-12 2008-09-18 Grünenthal GmbH Use of 1-phenyl-3-dimethylamino-propane compounds for the therapy of neuropathy pain
EP1985292A1 (en) 2007-04-23 2008-10-29 Grünenthal GmbH Titration of tapentadol
RS55769B1 (en) 2007-11-23 2017-07-31 Gruenenthal Gmbh TAPENTADOL COMPOSITIONS
CA2713128C (en) 2008-01-25 2016-04-05 Gruenenthal Gmbh Pharmaceutical dosage form
RU2673882C1 (en) 2008-10-30 2018-12-03 Грюненталь Гмбх New and effective medicinal forms of tapentadol
WO2010100477A2 (en) 2009-03-03 2010-09-10 Shire Llc Amino acid and peptide carbamate prodrugs of tapentadol and uses thereof
US20100272815A1 (en) 2009-04-28 2010-10-28 Actavis Group Ptc Ehf Amorphous form of tapentadol hydrochloride
US20110190267A1 (en) * 2010-01-05 2011-08-04 Shire Pharmaceuticals, Inc. Prodrugs of opioids and uses thereof
ES2829386T3 (en) * 2010-03-30 2021-05-31 Phosphagenics Ltd Transdermal administration patch
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ES2910085T3 (en) * 2011-03-04 2022-05-11 Gruenenthal Gmbh Semisolid aqueous pharmaceutical composition containing tapentadol

Also Published As

Publication number Publication date
DK2680834T3 (en) 2017-12-04
AU2017200040A1 (en) 2017-02-02
EP3290029A1 (en) 2018-03-07
AU2012224954C1 (en) 2017-04-06
EA033171B1 (en) 2019-09-30
MX2013010100A (en) 2013-10-01
US20160346229A1 (en) 2016-12-01
MX344473B (en) 2016-12-16
HRP20171836T1 (en) 2017-12-29
KR101911362B1 (en) 2018-10-25
JP6027549B2 (en) 2016-11-16
AU2017200040B2 (en) 2018-09-06
BR112013022556A2 (en) 2016-12-06
CA2828637C (en) 2019-06-11
KR20180116463A (en) 2018-10-24
BR112013022556A8 (en) 2018-01-16
IL227826A0 (en) 2013-09-30
CY1119725T1 (en) 2018-06-27
US9446008B2 (en) 2016-09-20
KR20140013020A (en) 2014-02-04
WO2012119729A1 (en) 2012-09-13
JP6670283B2 (en) 2020-03-18
AU2012224954A1 (en) 2013-09-19
AU2012224954B2 (en) 2016-10-20
ES2910085T3 (en) 2022-05-11
JP2014506900A (en) 2014-03-20
ES2654407T3 (en) 2018-02-13
EP2680834B1 (en) 2017-10-18
PT3766489T (en) 2022-04-07
ZA201306480B (en) 2014-05-28
EA201600442A1 (en) 2017-02-28
EP3290029B1 (en) 2020-09-02
NO2680834T3 (en) 2018-03-17
IL227826B (en) 2018-04-30
KR102039320B1 (en) 2019-11-01
CN103501774A (en) 2014-01-08
SI2680834T1 (en) 2018-01-31
LT2680834T (en) 2018-01-10
IL258357A (en) 2018-05-31
JP6259042B2 (en) 2018-01-10
EP3766489B1 (en) 2022-03-16
EP2680834A1 (en) 2014-01-08
PL2680834T3 (en) 2018-03-30
MX374468B (en) 2025-03-06
US20120225950A1 (en) 2012-09-06
JP2018065839A (en) 2018-04-26
RS56692B1 (en) 2018-03-30
EA201300988A1 (en) 2014-06-30
PT2680834T (en) 2018-01-25
EP3766489A1 (en) 2021-01-20
EA025194B1 (en) 2016-11-30
CA2828637A1 (en) 2012-09-13
JP2017039756A (en) 2017-02-23
US20180133174A1 (en) 2018-05-17

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