HUP0202758A3 - Isomeric fused pyrrolocarbazoles and isoindolones and their intermediates, process for their preparation and pharmaceutical compositions containing them - Google Patents

Isomeric fused pyrrolocarbazoles and isoindolones and their intermediates, process for their preparation and pharmaceutical compositions containing them

Info

Publication number: HUP0202758A3
Authority: HU; Hungary
Prior art keywords: isoindolones; intermediates; preparation; pharmaceutical compositions; compositions containing
Prior art date: 1999-08-20

Application number

HU0202758A

Other languages

English (en)

Original Assignee

Cephalon Inc West Chester

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-20

Filing date

2000-08-18

Publication date

2004-12-28

2000-08-18 Application filed by Cephalon Inc West Chester filed Critical Cephalon Inc West Chester

2002-12-28 Publication of HUP0202758A2 publication Critical patent/HUP0202758A2/hu

2004-12-28 Publication of HUP0202758A3 publication Critical patent/HUP0202758A3/hu

Links

239000000543 intermediate Substances 0.000 title 1
XTBAPWCYTNCZTO-UHFFFAOYSA-N isoindol-1-one Chemical class C1=CC=C2C(=O)N=CC2=C1 XTBAPWCYTNCZTO-UHFFFAOYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
QNMMYUBZGLXCCK-UHFFFAOYSA-N pyrrolo[3,2-a]carbazole Chemical class N1=C2C=CC=CC2=C2C1=C1C=CN=C1C=C2 QNMMYUBZGLXCCK-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Urology & Nephrology (AREA)
Psychology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Dermatology (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Pulmonology (AREA)
Ophthalmology & Optometry (AREA)
Reproductive Health (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Pyrrole Compounds (AREA)
Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Indole Compounds (AREA)

HU0202758A 1999-08-20 2000-08-18 Isomeric fused pyrrolocarbazoles and isoindolones and their intermediates, process for their preparation and pharmaceutical compositions containing them HUP0202758A3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US15036799P	1999-08-20	1999-08-20
US09/640,825 US6399780B1 (en)	1999-08-20	2000-08-17	Isomeric fused pyrrolocarbazoles and isoindolones
PCT/US2000/022724 WO2001014380A1 (en)	1999-08-20	2000-08-18	Isomeric fused pyrrolocarbazoles and isoindolones

Publications (2)

Publication Number	Publication Date
HUP0202758A2 HUP0202758A2 (hu)	2002-12-28
HUP0202758A3 true HUP0202758A3 (en)	2004-12-28

Family

ID=26847579

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0202758A HUP0202758A3 (en)	1999-08-20	2000-08-18	Isomeric fused pyrrolocarbazoles and isoindolones and their intermediates, process for their preparation and pharmaceutical compositions containing them

Country Status (26)

Country	Link
US (4)	US6399780B1 (hu)
EP (1)	EP1206473B1 (hu)
JP (1)	JP4776842B2 (hu)
KR (1)	KR100756686B1 (hu)
CN (1)	CN1370173A (hu)
AT (1)	ATE280172T1 (hu)
AU (1)	AU776475C (hu)
BG (1)	BG65545B1 (hu)
BR (1)	BR0013811A (hu)
CA (1)	CA2381885C (hu)
CZ (1)	CZ2002616A3 (hu)
DE (1)	DE60015153T2 (hu)
EA (1)	EA005920B1 (hu)
ES (1)	ES2230140T3 (hu)
HK (1)	HK1046904B (hu)
HU (1)	HUP0202758A3 (hu)
IL (2)	IL148180A0 (hu)
IS (1)	IS2186B (hu)
MX (1)	MXPA02001789A (hu)
NO (1)	NO323375B1 (hu)
NZ (1)	NZ517174A (hu)
PL (1)	PL354180A1 (hu)
PT (1)	PT1206473E (hu)
SK (1)	SK286805B6 (hu)
TR (1)	TR200200474T2 (hu)
WO (1)	WO2001014380A1 (hu)

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US6399780B1 (en) *	1999-08-20	2002-06-04	Cephalon, Inc.	Isomeric fused pyrrolocarbazoles and isoindolones
US7122679B2 (en) *	2000-05-09	2006-10-17	Cephalon, Inc.	Multicyclic compounds and the use thereof
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UA80447C2 (en) *	2002-10-08	2007-09-25		Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
ZA200502612B (en)	2002-10-08	2007-07-25	Rinat Neuroscience Corp	Methods for treating post-surgical pain by administering a nerve crowth factor antagonist and compositions containing the same
WO2005000194A2 (en) *	2002-10-08	2005-01-06	Rinat Neuroscience Corp.	Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same
US9498530B2 (en)	2002-12-24	2016-11-22	Rinat Neuroscience Corp.	Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
DK2270048T3 (en)	2002-12-24	2016-01-18	Rinat Neuroscience Corp	Anti-NGF antibodies and methods for their use
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BRPI0407375A (pt) *	2003-02-19	2006-02-07	Rinat Neuroscience Corp	Métodos para tratar dor por meio da administração de um antagonista do fator de crescimento neural e u nsaid e composições contendo os mesmos
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EP3372614B1 (en)	2004-04-07	2022-06-08	Rinat Neuroscience Corp.	Methods for treating bone cancer pain by administering a nerve growth factor antagonist
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BRPI0606793A8 (pt)	2005-02-04	2018-03-13	Astrazeneca Ab	composto ou um sal farmaceuticamente aceitável do mesmo, processo para a preparação e uso do mesmo, métodos para a inibição da atividade de trk, para o tratamento ou profilaxia de câncer e para a produção de um efeito anti-proliferativo em um animal de sangue quente, e, composição farmacêutica
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JP2009513615A (ja)	2005-10-28	2009-04-02	アストラゼネカアクチボラグ	癌の治療においてチロシンキナーゼ阻害剤として使用するための４−（３−アミノピラゾール）ピリミジン誘導体
JP5182088B2 (ja)	2006-04-19	2013-04-10	アステラス製薬株式会社	アゾールカルボキサミド誘導体
US20080021013A1 (en) *	2006-07-21	2008-01-24	Cephalon, Inc.	JAK inhibitors for treatment of myeloproliferative disorders
JP2010500961A (ja) *	2006-08-02	2010-01-14	武田薬品工業株式会社	α−カルボリン誘導体およびその製造方法
CA2668744C (en) *	2006-11-17	2015-09-15	Queen's University At Kingston	Compounds and methods for treating protein folding disorders
WO2010131855A2 (ko)	2009-05-13	2010-11-18	덕산하이메탈(주)	오원자 헤테로고리를 포함하는 화합물 및 이를 이용한 유기전기소자, 그 단말
JP2010524911A (ja) *	2007-04-18	2010-07-22	アストラゼネカアクチボラグ	５−アミノピラゾール−３−イル−３Ｈ−イミダゾ［４，５−ｂ］ピリジン誘導体と癌の治療のためのその使用
WO2008135786A1 (en) *	2007-05-04	2008-11-13	Astrazeneca Ab	Amino-thiazolyl- pyrimidine derivatives and their use for the treatment of cancer
UA99459C2 (en) *	2007-05-04	2012-08-27	Астразенека Аб	9-(pyrazol-3-yl)- 9h-purine-2-amine and 3-(pyraz0l-3-yl)-3h-imidazo[4,5-b]pyridin-5-amine derivatives and their use for the treatment of cancer
EP2206707B1 (en)	2007-10-24	2014-07-23	Astellas Pharma Inc.	Azolecarboxamide compound or salt thereof
WO2009088054A1 (ja)	2008-01-11	2009-07-16	Astellas Pharma Inc.	精巣の疼痛又は不快感行動及び頻尿併発モデル動物
KR20110017445A (ko) *	2008-06-11	2011-02-21	아스트라제네카 아베	암 및 골수증식성 장애의 치료에 유용한 트리시클릭 2,4-디아미노-ｌ,3,5-트리아진 유도체
BRPI0919488A2 (pt) *	2008-09-30	2015-12-01	Astrazeneca Ab	composto, uso de um composto, método para tratar câncer em um animal de sangue quente, composição farmacêutica, e, processo para preparar um composto
CA2742790C (en)	2008-11-19	2018-02-13	Cephalon, Inc.	Novel forms of an indazolo[5,4-a]pyrrolo [3,4-c] carbazole compound
CN102482279B (zh) *	2009-03-30	2015-08-12	德山新勒克斯	有机电子装置及其化合物与终端机
WO2012024650A2 (en)	2010-08-19	2012-02-23	Abbott Laboratories	Anti-ngf antibodies and their use
KR101497122B1 (ko) *	2011-08-09	2015-03-06	덕산네오룩스 주식회사	2개 이상의 오원자 헤테로고리를 포함하는 화합물 및 이를 이용한 유기전기소자, 그 단말
TWI585088B (zh)	2012-06-04	2017-06-01	第一三共股份有限公司	作爲激酶抑制劑之咪唑并［１，２－ｂ］嗒衍生物
CA2875783C (en)	2012-06-06	2018-12-11	Zoetis Llc	Caninized anti-ngf antibodies and methods thereof
KR101478884B1 (ko)	2012-12-24	2015-01-05	충남대학교산학협력단	비스인돌일말레이미드계 화합물 및 이의 제조방법
MX2020004536A (es)	2017-11-23	2020-08-03	Biomed X Gmbh	Derivados de pirimidina como inhibidores del receptor de tropomiosina quinasa (trka).
BR112020017701A2 (pt)	2018-03-12	2020-12-29	Zoetis Services Llc	Anticorpos anti-ngf e métodos dos mesmos

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2000
- 2000-08-17 US US09/640,825 patent/US6399780B1/en not_active Expired - Lifetime
- 2000-08-18 DE DE60015153T patent/DE60015153T2/de not_active Expired - Lifetime
- 2000-08-18 MX MXPA02001789A patent/MXPA02001789A/es active IP Right Grant
- 2000-08-18 AT AT00954136T patent/ATE280172T1/de active
- 2000-08-18 ES ES00954136T patent/ES2230140T3/es not_active Expired - Lifetime
- 2000-08-18 PT PT00954136T patent/PT1206473E/pt unknown
- 2000-08-18 WO PCT/US2000/022724 patent/WO2001014380A1/en not_active Ceased
- 2000-08-18 CA CA002381885A patent/CA2381885C/en not_active Expired - Fee Related
- 2000-08-18 IL IL14818000A patent/IL148180A0/xx active IP Right Grant
- 2000-08-18 AU AU66471/00A patent/AU776475C/en not_active Ceased
- 2000-08-18 PL PL00354180A patent/PL354180A1/xx unknown
- 2000-08-18 HU HU0202758A patent/HUP0202758A3/hu unknown
- 2000-08-18 EP EP00954136A patent/EP1206473B1/en not_active Expired - Lifetime
- 2000-08-18 NZ NZ517174A patent/NZ517174A/en unknown
- 2000-08-18 EA EA200200271A patent/EA005920B1/ru not_active IP Right Cessation
- 2000-08-18 KR KR1020027002117A patent/KR100756686B1/ko not_active Expired - Fee Related
- 2000-08-18 CN CN00811850A patent/CN1370173A/zh active Pending
- 2000-08-18 BR BR0013811-8A patent/BR0013811A/pt not_active Application Discontinuation
- 2000-08-18 CZ CZ2002616A patent/CZ2002616A3/cs unknown
- 2000-08-18 SK SK246-2002A patent/SK286805B6/sk not_active IP Right Cessation
- 2000-08-18 TR TR2002/00474T patent/TR200200474T2/xx unknown
- 2000-08-18 HK HK02108409.6A patent/HK1046904B/en not_active IP Right Cessation
- 2000-08-18 JP JP2001518711A patent/JP4776842B2/ja not_active Expired - Fee Related
2002
- 2002-02-01 US US10/062,159 patent/US6635669B2/en not_active Expired - Lifetime
- 2002-02-12 IS IS6266A patent/IS2186B/is unknown
- 2002-02-14 IL IL148180A patent/IL148180A/en not_active IP Right Cessation
- 2002-02-19 NO NO20020809A patent/NO323375B1/no not_active IP Right Cessation
- 2002-02-21 BG BG106423A patent/BG65545B1/bg unknown
2003
- 2003-04-24 US US10/422,164 patent/US6872746B2/en not_active Expired - Fee Related
2005
- 2005-01-05 US US11/029,330 patent/US7291732B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR20020038730A (ko)	2002-05-23
WO2001014380A1 (en)	2001-03-01
NZ517174A (en)	2003-09-26
IS6266A (is)	2002-02-12
EA200200271A1 (ru)	2002-08-29
KR100756686B1 (ko)	2007-09-07
SK2462002A3 (en)	2002-12-03
NO20020809D0 (no)	2002-02-19
DE60015153T2 (de)	2006-02-09
US6635669B2 (en)	2003-10-21
BG65545B1 (bg)	2008-11-28
BR0013811A (pt)	2002-07-23
CA2381885A1 (en)	2001-03-01
IS2186B (is)	2006-12-15
CA2381885C (en)	2009-10-27
NO20020809L (no)	2002-02-20
IL148180A (en)	2008-04-13
TR200200474T2 (tr)	2002-06-21
BG106423A (en)	2002-09-30
AU776475B2 (en)	2004-09-09
AU6647100A (en)	2001-03-19
HK1046904A1 (en)	2003-01-30
IL148180A0 (en)	2002-09-12
US7291732B2 (en)	2007-11-06
US6872746B2 (en)	2005-03-29
ATE280172T1 (de)	2004-11-15
EP1206473B1 (en)	2004-10-20
US20020147341A1 (en)	2002-10-10
SK286805B6 (sk)	2009-05-07
DE60015153D1 (de)	2004-11-25
JP4776842B2 (ja)	2011-09-21
EP1206473A1 (en)	2002-05-22
HK1046904B (en)	2005-05-06
US20030216419A1 (en)	2003-11-20
MXPA02001789A (es)	2003-07-14
PL354180A1 (en)	2003-12-29
ES2230140T3 (es)	2005-05-01
JP2003507480A (ja)	2003-02-25
EA005920B1 (ru)	2005-08-25
CZ2002616A3 (cs)	2003-04-16
CN1370173A (zh)	2002-09-18
US20050107458A1 (en)	2005-05-19
AU776475C (en)	2005-04-07
HUP0202758A2 (hu)	2002-12-28
US6399780B1 (en)	2002-06-04
NO323375B1 (no)	2007-04-16
PT1206473E (pt)	2005-01-31

Legal Events

Date	Code	Title	Description
2013-05-28	FD9A	Lapse of provisional protection due to non-payment of fees

Publication	Publication Date	Title
HUP0202758A3 (en)	2004-12-28	Isomeric fused pyrrolocarbazoles and isoindolones and their intermediates, process for their preparation and pharmaceutical compositions containing them
HUP0102313A3 (en)	2002-10-28	Imidazo pyridine derivatives, process for their preparation pharmaceutical compositions containing the same and intermediates
HUP0102307A3 (en)	2002-02-28	Bispidine derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates
HUP0301187A3 (en)	2010-03-29	Novel benzyl-piperidine-derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0204245A3 (en)	2004-12-28	Novel n-azabicyclo-amide derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0104199A3 (en)	2002-12-28	Substituted pyrimido pyrimidinone derivatives, pharmaceutical compositions containing the same, process for the preparation thereof and intermediates
HUP0203107A3 (en)	2004-06-28	Novel spiro compounds, process for their preparation and pharmaceutical compositions containing them
HUP0003844A3 (en)	2002-11-28	Novel spiroazabicyclic heterocyclic compounds, process for their preparation, their use and pharmaceutical compositions containing them
HUP0302257A3 (en)	2007-03-28	4-hydrazino-5-hydroxy-5-pyrazol derivatives, pharmaceutical compositions containing them, process for producing them and their intermediates
HUP0201122A3 (en)	2003-11-28	Pyrimidinone compounds, process for their preparation and pharmaceutical compositions containing them
HUP0002842A3 (en)	2002-01-28	Substituted imidazoles, process for producing them, pharmaceutical compositions containing them, their use and their intermediates
HUP0203316A3 (en)	2004-07-28	Amino-triazolopyridine derivatives, process for their preparation and pharmaceutical compositions containing them
IL135920A0 (en)	2001-05-20	2-aryl -8-oxodihydropurine derivative, process for the preparation thereof, pharmaceutical composition containing the same and intermediate therefor
HUP0301069A3 (en)	2004-09-28	Novel biarylcarboxamides, process for their preparation, pharmaceutical compositions containing them and their use
HUP0203183A3 (en)	2006-02-28	Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use
HUP0203052A3 (en)	2004-06-28	Bicyclic imidazo-3-yl-amine derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0202731A3 (en)	2003-10-28	O-anisamide derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0105108A3 (en)	2002-11-28	Amide compounds, process for their preparation and pharmaceutical compositions containing them
HUP0102512A3 (en)	2002-08-28	Bridged indenopyrrolocarbazoles, process for their preparation, pharmaceutical compositions containing them and their use
HUP0201516A3 (en)	2003-03-28	13-methyl-erythromycin derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0203140A3 (en)	2004-06-28	Bicyclic imidazo-5-yl-amine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0201753A3 (en)	2004-12-28	Pyridopyranoazepine derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0201402A3 (en)	2003-12-29	Bis-sulfonamides, process for their preparation and pharmaceutical compositions containing them
HUP0202075A3 (en)	2003-03-28	Substituted 2-dialkylaminoalkylbiphenyl derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0003413A3 (en)	2003-11-28	New fused pyridine derivatives, process for their preparation and pharmaceutical compositions containing them