HUP9702348A2 - New anticoagulant glycosides and pharmaceutical compositions containing them - Google Patents

New anticoagulant glycosides and pharmaceutical compositions containing them

Info

Publication number
HUP9702348A2
HUP9702348A2 HU9702348A HUP9702348A HUP9702348A2 HU P9702348 A2 HUP9702348 A2 HU P9702348A2 HU 9702348 A HU9702348 A HU 9702348A HU P9702348 A HUP9702348 A HU P9702348A HU P9702348 A2 HUP9702348 A2 HU P9702348A2
Authority
HU
Hungary
Prior art keywords
glycosides
pharmaceutical compositions
compositions containing
new anticoagulant
compounds
Prior art date
Application number
HU9702348A
Other languages
Hungarian (hu)
Inventor
dr. Bozó Éva Kovácsné
János Kuszmann
Gabriella Szabó
Éva Barabás
Sándor Boros
Lászlóné Kenyeres
Ottóné Orbán
Éva Kaszás
Imre Moravcsik
Gáborné Szeker
Ferwagner Mónika Turuczné
Beáta Fehér
dr. Kedves Rita Soukupné
Original Assignee
Richter Gedeon Vegyészeti Gyár Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyészeti Gyár Rt. filed Critical Richter Gedeon Vegyészeti Gyár Rt.
Priority to HU97023489702348A priority Critical patent/HUP9702348A3/en
Publication of HU9702348D0 publication Critical patent/HU9702348D0/en
Priority to PCT/HU1998/000099 priority patent/WO1999028312A1/en
Priority to AU13467/99A priority patent/AU1346799A/en
Publication of HUP9702348A2 publication Critical patent/HUP9702348A2/en
Publication of HUP9702348A3 publication Critical patent/HUP9702348A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/08—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium
    • C07H5/10—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to sulfur, selenium or tellurium to sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

A találmány tárgyát (I) általánős képletű 1,5-ditiő-L- és D-mannőpiranőzidők, ahől R jelentése cianő-, nitrő-, amidinő-, aminő-tiőkarbőnil- vagyacetamidő-csőpőrt, és lehetséges esetben ezek szerves vagy szervetlensavval képzett savaddíciós sói, valamint e vegyületeket hatóanyagkénttartalmazó gyógyszerkészítmények képezik. A találmány szerintivegyületek értékes őrális véralvadásgátló hatással rendelkeznek. ŕThe subject of the invention is 1,5-dithio-L- and D-mannopyranozides of general formula (I), where R is cyano-, nitro-, amidino-, aminothiocarbonyl or acetamide powder, and if possible these are acid addition compounds formed with organic or inorganic acids salts, as well as pharmaceutical preparations containing these compounds as active ingredients. The compounds according to the invention have a valuable oral anticoagulant effect. ŕ

HU97023489702348A 1997-12-04 1997-12-04 New anticoagulant glycosides and pharmaceutical conew anticoagulant glycosides and pharmaceutical compositions containing them mpositions containing them HUP9702348A3 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
HU97023489702348A HUP9702348A3 (en) 1997-12-04 1997-12-04 New anticoagulant glycosides and pharmaceutical conew anticoagulant glycosides and pharmaceutical compositions containing them mpositions containing them
PCT/HU1998/000099 WO1999028312A1 (en) 1997-12-04 1998-12-03 Novel anticoagulant glycosides and pharmaceutical compositions thereof
AU13467/99A AU1346799A (en) 1997-12-04 1998-12-03 Novel anticoagulant glycosides and pharmaceutical compositions thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU97023489702348A HUP9702348A3 (en) 1997-12-04 1997-12-04 New anticoagulant glycosides and pharmaceutical conew anticoagulant glycosides and pharmaceutical compositions containing them mpositions containing them

Publications (3)

Publication Number Publication Date
HU9702348D0 HU9702348D0 (en) 1998-03-02
HUP9702348A2 true HUP9702348A2 (en) 1999-08-30
HUP9702348A3 HUP9702348A3 (en) 2000-12-28

Family

ID=89995815

Family Applications (1)

Application Number Title Priority Date Filing Date
HU97023489702348A HUP9702348A3 (en) 1997-12-04 1997-12-04 New anticoagulant glycosides and pharmaceutical conew anticoagulant glycosides and pharmaceutical compositions containing them mpositions containing them

Country Status (3)

Country Link
AU (1) AU1346799A (en)
HU (1) HUP9702348A3 (en)
WO (1) WO1999028312A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201603288XA (en) 2012-03-28 2016-05-30 Fujifilm Corp Salt Of 1-(2-Deoxy-2-Fluoro-4-Thio-beta-D-Arabinofuranosyl)Cytosine
KR20170001722A (en) 2012-08-13 2017-01-04 후지필름 가부시키가이샤 Synthesis intermediates of 1- (2-deoxy-2-fluoro-4-thio- 硫 -D-arabinofuranosyl) cytosine, synthetic intermediates of thionucleosides,
EP3109245B1 (en) 2014-02-18 2018-01-03 FUJIFILM Corporation Method for producting thiolane skeleton-type glycoconjugate, and thiolane skeleton-type glycoconjugate
JP6204223B2 (en) * 2014-02-19 2017-09-27 富士フイルム株式会社 Method for producing thiopyranose compound, etc.
TWI678373B (en) 2014-10-31 2019-12-01 日商富士軟片股份有限公司 Thionucleoside derivative or its salt and pharmaceutical composition
IL265044B2 (en) 2016-08-31 2025-02-01 Fujifilm Corp An anti-tumor composition comprising the compounds nab-paclitaxel and 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine, a kit comprising these compounds and uses thereof
WO2019146130A1 (en) 2018-01-29 2019-08-01 富士フイルム株式会社 Antitumor agent for biliary cancer and treatment method of biliary cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0117413B1 (en) * 1980-12-09 1987-08-26 Seikagaku Kogyo Co. Ltd. D-xylopyranoside series compounds and therapeutical compositions containing same
IE63544B1 (en) * 1988-10-18 1995-05-17 Fournier Ind & Sante Novel Beta-d-phenylthioxylosides their method of preparation and their use in therapy

Also Published As

Publication number Publication date
HU9702348D0 (en) 1998-03-02
AU1346799A (en) 1999-06-16
WO1999028312A1 (en) 1999-06-10
HUP9702348A3 (en) 2000-12-28

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