HUT38335A - Process for producing indol derivatives and pharmaceutical compositions containing them - Google Patents
Process for producing indol derivatives and pharmaceutical compositions containing themInfo
- Publication number
- HUT38335A HUT38335A HU844360A HU436084A HUT38335A HU T38335 A HUT38335 A HU T38335A HU 844360 A HU844360 A HU 844360A HU 436084 A HU436084 A HU 436084A HU T38335 A HUT38335 A HU T38335A
- Authority
- HU
- Hungary
- Prior art keywords
- producing
- pharmaceutical compositions
- compositions containing
- substd
- opt
- Prior art date
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- DBTDEFJAFBUGPP-UHFFFAOYSA-N Methanethial Chemical compound S=C DBTDEFJAFBUGPP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 125000000814 indol-3-yl group Chemical group [H]C1=C([H])C([H])=C2N([H])C([H])=C([*])C2=C1[H] 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- -1 methylenedioxy Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
Indole derivs. of formula (I) and their physiologically acceptable acid addn. salts are new: Ind= indol-3-yl substd. by CH2OH or COW and opt. also by 1 or 2 alkyl, alkoxy, OH, F, Cl or Br; W= H, OH, alkoxy or amino (opt. substd. by 1 or 2 alkyl); A= (CH2)n or CH2S(O)xCH2CH2; n= 2-5; x= 0, 1 or 2; both Y are H, or together they form a double bond; one Z= Ar and the other is H; Ar= phenyl (opt. substd. by 1 or 2 of alkoxy and/or OH, or by methylenedioxy) or is 2- or 3-thienyl; all alkyl have 1-4C.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3324632 | 1983-11-25 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUT38335A true HUT38335A (en) | 1986-05-28 |
| HU193304B HU193304B (en) | 1987-09-28 |
Family
ID=6203458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU844360A HU193304B (en) | 1983-11-25 | 1984-11-23 | Process for preparing indole derivatives and pharmaceutical compositions comprising the same as active substance |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HU193304B (en) |
-
1984
- 1984-11-23 HU HU844360A patent/HU193304B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HU193304B (en) | 1987-09-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |