HUT43037A - Process for preparing novel carboxylic acid derivatives and pharmaceutical compositions comprising the same as active substance - Google Patents
Process for preparing novel carboxylic acid derivatives and pharmaceutical compositions comprising the same as active substanceInfo
- Publication number
- HUT43037A HUT43037A HU863741A HU374186A HUT43037A HU T43037 A HUT43037 A HU T43037A HU 863741 A HU863741 A HU 863741A HU 374186 A HU374186 A HU 374186A HU T43037 A HUT43037 A HU T43037A
- Authority
- HU
- Hungary
- Prior art keywords
- carboxylic acid
- pharmaceutical compositions
- same
- active substance
- opt
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 125000003754 ethoxycarbonyl group Chemical group C(=O)(OCC)* 0.000 abstract 1
- XSXHWVKGUXMUQE-UHFFFAOYSA-N osmium dioxide Inorganic materials O=[Os]=O XSXHWVKGUXMUQE-UHFFFAOYSA-N 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The use of aryl- and aryloxy-alkanoic acid derivs. of formula (I) and their physiologically innocuous salts, esters and amides for combatting diabetes is new (where R1=H or opt. substd. aryl or aryloxy; R2=H, lower alkyl or -A-R1; A=opt. branched, opt. unsatd. 1-18C alkylene; X=CN, COOEt, aminocarbonyl, amidosulphonyl or -B-R3; B=O, S, SO, SO2, OSO2, NHSO2 or CO; R3= alkyl, CF3, cycloalkyl or aralkyl, aralkenyl or aryl in which the acyl moiety is opt. substd. Cpds. of formula (I) and their physiologically innocuous salts, esters and amides are new and claimed per se when R1 is other than H; A is (un)branched, unsatd. 3-8C alkylene; X is amidosulphonyl or -B-R3; and B is other than CO. (Dwg.0/0)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP1986/000406 WO1987000521A2 (en) | 1985-07-16 | 1986-07-10 | New carboxylic acid derivatives, their manufacturing process, use and medicines containing these compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUT43037A true HUT43037A (en) | 1987-09-28 |
Family
ID=8165125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU863741A HUT43037A (en) | 1986-07-10 | 1986-07-10 | Process for preparing novel carboxylic acid derivatives and pharmaceutical compositions comprising the same as active substance |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HUT43037A (en) |
-
1986
- 1986-07-10 HU HU863741A patent/HUT43037A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DFC4 | Cancellation of temporary prot. due to refusal |