HUT53129A - Process for producing heparin fractions having anti-hiv activity - Google Patents

Process for producing heparin fractions having anti-hiv activity

Info

Publication number
HUT53129A
HUT53129A HU9094A HU9490A HUT53129A HU T53129 A HUT53129 A HU T53129A HU 9094 A HU9094 A HU 9094A HU 9490 A HU9490 A HU 9490A HU T53129 A HUT53129 A HU T53129A
Authority
HU
Hungary
Prior art keywords
hiv activity
heparin fractions
producing heparin
producing
sulfated polysaccharides
Prior art date
Application number
HU9094A
Other languages
Hungarian (hu)
Other versions
HU900094D0 (en
HU203373B (en
Inventor
Alan Douglas Cardin
Richard Lee Jackson
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of HU900094D0 publication Critical patent/HU900094D0/en
Publication of HUT53129A publication Critical patent/HUT53129A/en
Publication of HU203373B publication Critical patent/HU203373B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Various peptides having affinity for sulfated polysaccharides such as heparin, dextran sulfate and pentosan polysulfate are bound to resins and used in affinity chromatography to prepare anti-HIV sulfated polysaccharides.
HU9094A 1989-01-11 1990-01-10 Process for producing heparin having anti-hiv activity HU203373B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29585689A 1989-01-11 1989-01-11
US37579589A 1989-07-05 1989-07-05

Publications (3)

Publication Number Publication Date
HU900094D0 HU900094D0 (en) 1990-03-28
HUT53129A true HUT53129A (en) 1990-09-28
HU203373B HU203373B (en) 1991-07-29

Family

ID=26969370

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9094A HU203373B (en) 1989-01-11 1990-01-10 Process for producing heparin having anti-hiv activity

Country Status (11)

Country Link
EP (1) EP0406512B1 (en)
JP (1) JPH02263801A (en)
KR (1) KR0159774B1 (en)
AT (1) ATE90566T1 (en)
CA (1) CA2007258A1 (en)
DE (1) DE69001957T2 (en)
DK (1) DK0406512T3 (en)
ES (1) ES2058606T3 (en)
HU (1) HU203373B (en)
IE (1) IE63167B1 (en)
IL (1) IL93003A0 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5456924A (en) * 1988-12-23 1995-10-10 Immunotec Research Corporation Ltd. Method of treatment of HIV-seropositive individuals with dietary whey proteins
JP3615785B2 (en) * 1994-04-28 2005-02-02 テルモ株式会社 HIV and related material removal materials
ITMI20011633A1 (en) * 2001-07-27 2003-01-27 San Raffaele Centro Fond USE OF SUPER-SULFATED BACTERIAL POLYSACCHARIDES INHIBITORS OF HIV

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4119774A (en) * 1976-03-05 1978-10-10 Ab Kabi Heparin purification method
EP0292663B1 (en) * 1987-05-25 1995-06-14 Research Development Corporation Of Japan A method for producing vitronectin
EP0293826A3 (en) * 1987-06-02 1989-05-10 Stichting REGA V.Z.W. Therapeutic and prophylactic application of sulfated polysaccharides against aids

Also Published As

Publication number Publication date
JPH02263801A (en) 1990-10-26
HU900094D0 (en) 1990-03-28
DE69001957D1 (en) 1993-07-22
DK0406512T3 (en) 1993-08-09
CA2007258A1 (en) 1990-07-11
ATE90566T1 (en) 1993-07-15
KR0159774B1 (en) 1998-11-16
EP0406512B1 (en) 1993-06-16
DE69001957T2 (en) 1993-09-23
HU203373B (en) 1991-07-29
IE63167B1 (en) 1995-03-22
IE900083L (en) 1990-07-11
ES2058606T3 (en) 1994-11-01
EP0406512A1 (en) 1991-01-09
KR900011788A (en) 1990-08-02
IL93003A0 (en) 1990-09-17

Similar Documents

Publication Publication Date Title
DK377888A (en) POLYSACCHARIDE
ATE76752T1 (en) BLOOD SUBSTITUTE.
AU5841090A (en) Sulphated polysaccharides, anticoagulant agent and anticomplementary agent obtained from brown algae fucuses and method of obtaining same
NL191308B (en) Lyophilized post-solution injectable preparation containing an anthracycline glycoside and process for the preparation of an injectable solution of an anthracycline glycoside.
DE3165361D1 (en) Sulfated polysaccharides, process for their preparation and their use as medicines
IE960853L (en) Vascular anticoagulant proteins
FR2597484B1 (en) GLYCOSAMINOGLYCANS OF THE HEPARIN OR HEPARANE-SULPHATE TYPE WITH ACTIVITY ON CELL DIVISION AND DIFFERENTIATION, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATIONS.
EP0515516A4 (en) Totally synthetic affinity reagents
ES2098237T3 (en) SUITABLE ADSORBENT TO ELIMINATE BIOMACROMOLECULAS, IN PARTICULAR LDL AND ENDOTOXINES, FROM EXTRACORPORAL CIRCULATION OF BLOOD.
EP0333243A3 (en) Sulphated k5 antigen and sulphated k5 antigen fragments
NO913887L (en) INCLUSION COMPLEXES WITH SILYBININ, PREPARATION OF THESE AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE
DE69020963D1 (en) Zeolite agglomeration process and product.
HUT53129A (en) Process for producing heparin fractions having anti-hiv activity
NZ221065A (en) Conjugates of antibodies and toxins with sulphur-containing linking groups
PL316935A1 (en) Heparin bonding protein for treating septicaemia and method of obtaining such protein
FI882683L (en) Compression process using degraded lignocellulosic materials and the product thus produced
DE3366933D1 (en) Antithrombin-heparin complex
KR890002228A (en) Method for Purifying Placental Tissue Protein PP 4
CA2213577A1 (en) A process for the preparation of factor ix from biological sources
EP0361490A3 (en) Sulfated oligosaccharides and derivatives thereof
FI853095L (en) FOERFARANDE FOER AOTERVINNING AV EN GELBILDANDE POLYSACKARID, AOTERVUNNEN POLYSACKARID OCH GEL BILDAD DAERMED.
HU905943D0 (en) Process for producing anti-coagulant and anti-helmintic proteins and their utilization
GR910300053T1 (en) Abutment to limit the stroke of vehicle suspensions or the like, having progressive stiffness characteristics and being self-stabilizing under compression
DE69034209D1 (en) 2'-DEOXY-4'-THIORIBONUCLEOSIDE AS ANTIVIRAL AND ANTIBODY
AU8666891A (en) Toy road track module

Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee