HUT55358A - Process for producing benzylpyrrolidine derivatives with dopamin antagonist effect and pharmaceutical compositions comprising such compounds - Google Patents

Process for producing benzylpyrrolidine derivatives with dopamin antagonist effect and pharmaceutical compositions comprising such compounds Download PDF

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Publication number
HUT55358A
HUT55358A HU906917A HU691790A HUT55358A HU T55358 A HUT55358 A HU T55358A HU 906917 A HU906917 A HU 906917A HU 691790 A HU691790 A HU 691790A HU T55358 A HUT55358 A HU T55358A
Authority
HU
Hungary
Prior art keywords
formula
compound
pharmaceutically acceptable
pyrrolidine
propylamino
Prior art date
Application number
HU906917A
Other languages
English (en)
Hungarian (hu)
Inventor
E Lawrence Fisher
Joan M Caroon
Joseph M Muchowski
P Roberto Rosenkranz
L Deborah Mcclellend
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of HUT55358A publication Critical patent/HUT55358A/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
HU906917A 1989-10-30 1990-10-29 Process for producing benzylpyrrolidine derivatives with dopamin antagonist effect and pharmaceutical compositions comprising such compounds HUT55358A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42857789A 1989-10-30 1989-10-30

Publications (1)

Publication Number Publication Date
HUT55358A true HUT55358A (en) 1991-05-28

Family

ID=23699508

Family Applications (1)

Application Number Title Priority Date Filing Date
HU906917A HUT55358A (en) 1989-10-30 1990-10-29 Process for producing benzylpyrrolidine derivatives with dopamin antagonist effect and pharmaceutical compositions comprising such compounds

Country Status (12)

Country Link
EP (1) EP0426075A1 (fr)
JP (1) JPH03151358A (fr)
KR (1) KR910007875A (fr)
AU (1) AU636921B2 (fr)
CA (1) CA2028798A1 (fr)
FI (1) FI905325A7 (fr)
HU (1) HUT55358A (fr)
IE (1) IE903894A1 (fr)
IL (1) IL96150A0 (fr)
NO (1) NO904678L (fr)
PT (1) PT95731A (fr)
ZA (1) ZA908652B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995024390A1 (fr) * 1994-03-11 1995-09-14 Smithkline Beecham Plc Nouvelles piperidines substituees par phenyl(-alkyl/alkoxy)-1-aminoalkyle et pyrolidines utilisees comme antagonistes des canaux calciques
DE202013103273U1 (de) 2013-07-22 2014-10-23 Wegener International Gmbh Biegemaschine zum Biegen von Werkstücken aus thermoplastischem Kunststoff
WO2025217612A1 (fr) * 2024-04-11 2025-10-16 Dwulet Gregory Benzylpyrrolidines substituées et leurs utilisations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1186660A (en) * 1968-09-11 1970-04-02 Parke Davis & Co New Pyrrolidine Compounds and Methods for their Production
EP0071399A3 (fr) * 1981-07-22 1983-12-07 Syntex (U.S.A.) Inc. Pyrrolidines substituées comme régulateurs du système cardiovasculaire et agents antihypertensifs, leur fabrication et leur utilisation
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
AU629535B2 (en) * 1988-02-10 1992-10-08 A.H. Robins Company, Incorporated N-substituted-arylalkyl and arylalkylene aminoheterocyclics as cardiovascular antihistaminic and antisecretory agents

Also Published As

Publication number Publication date
EP0426075A1 (fr) 1991-05-08
FI905325A7 (fi) 1991-05-01
JPH03151358A (ja) 1991-06-27
CA2028798A1 (fr) 1991-05-01
PT95731A (pt) 1991-09-13
IE903894A1 (en) 1991-05-08
AU6553490A (en) 1991-05-02
NO904678L (no) 1991-05-02
FI905325A0 (fi) 1990-10-29
KR910007875A (ko) 1991-05-30
NO904678D0 (no) 1990-10-29
ZA908652B (en) 1992-07-29
AU636921B2 (en) 1993-05-13
IL96150A0 (en) 1991-07-18

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Legal Events

Date Code Title Description
DFC4 Cancellation of temporary protection due to refusal