HUT71220A - Chelate substances for targeted delivery of growth factors for bone regeneration, and pharmaceutical preparations containing them - Google Patents
Chelate substances for targeted delivery of growth factors for bone regeneration, and pharmaceutical preparations containing themInfo
- Publication number
- HUT71220A HUT71220A HU9403840A HU9403840A HUT71220A HU T71220 A HUT71220 A HU T71220A HU 9403840 A HU9403840 A HU 9403840A HU 9403840 A HU9403840 A HU 9403840A HU T71220 A HUT71220 A HU T71220A
- Authority
- HU
- Hungary
- Prior art keywords
- growth factors
- pharmaceutical preparations
- targeted delivery
- preparations containing
- bone regeneration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/547—Chelates, e.g. Gd-DOTA or Zinc-amino acid chelates; Chelate-forming compounds, e.g. DOTA or ethylenediamine being covalently linked or complexed to the pharmacologically- or therapeutically-active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C07F9/3817—Acids containing the structure (RX)2P(=X)-alk-N...P (X = O, S, Se)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90698092A | 1992-06-30 | 1992-06-30 | |
| US08/026,800 US5505931A (en) | 1993-03-04 | 1993-03-04 | Acid cleavable compounds, their preparation and use as bifunctional acid-labile crosslinking agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU9403840D0 HU9403840D0 (en) | 1995-02-28 |
| HUT71220A true HUT71220A (en) | 1995-11-28 |
Family
ID=26701672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9403840A HUT71220A (en) | 1992-06-30 | 1993-06-30 | Chelate substances for targeted delivery of growth factors for bone regeneration, and pharmaceutical preparations containing them |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0653941A1 (en) |
| JP (1) | JPH07508979A (en) |
| CN (1) | CN1092076A (en) |
| AU (1) | AU4660093A (en) |
| CA (1) | CA2139323A1 (en) |
| FI (1) | FI946156A7 (en) |
| HU (1) | HUT71220A (en) |
| IL (1) | IL106159A0 (en) |
| MX (1) | MX9303963A (en) |
| WO (1) | WO1994000145A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5462725A (en) * | 1993-05-06 | 1995-10-31 | The Dow Chemical Company | 2-pyridylmethylenepolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents |
| US6902584B2 (en) | 1995-10-16 | 2005-06-07 | Depuy Spine, Inc. | Bone grafting matrix |
| US5776193A (en) | 1995-10-16 | 1998-07-07 | Orquest, Inc. | Bone grafting matrix |
| GB9702978D0 (en) * | 1997-02-13 | 1997-04-02 | Ciba Geigy | Compounds |
| US6794371B1 (en) * | 1999-10-18 | 2004-09-21 | The Dow Chemical Company | Aminoalkylenephosphonates for treatment of bone disorders |
| WO2001028567A2 (en) * | 1999-10-18 | 2001-04-26 | The Dow Chemical Company | Aminoalkylenephosphonates for treatment of bone disorders |
| US6565828B2 (en) * | 2000-04-07 | 2003-05-20 | Bristol-Myers Squibb Company | Macrocyclic chelants for metallopharmaceuticals |
| EP1615639A2 (en) * | 2003-04-03 | 2006-01-18 | Semafore Pharmaceuticals, Inc. | Targeted bone marrow protection agents |
| EP1932850A1 (en) | 2006-12-11 | 2008-06-18 | Thermphos Trading GmbH | Phosphonate compounds |
| MX2017004520A (en) | 2014-10-14 | 2018-03-15 | Lynch Samuel | Compositions for treating wounds. |
| US20180215801A1 (en) | 2015-01-29 | 2018-08-02 | Board Of Trustees Of Michigan State University | Cryptic polypeptides and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5011913A (en) * | 1985-06-28 | 1991-04-30 | The Procter & Gamble Company | Diphosphonate-derivatized macromolecules |
| JPH02268190A (en) * | 1989-04-07 | 1990-11-01 | Fujisawa Pharmaceut Co Ltd | Conjugate from medical compound and diphosphonic acid derivative |
| US5208219A (en) * | 1991-02-14 | 1993-05-04 | Celtrix Pharmaceuticals Inc. | Method for inducing bone growth |
| AU662155B2 (en) * | 1991-05-10 | 1995-08-24 | Celtrix Pharmaceuticals, Inc. | Targeted delivery of bone growth factors |
-
1993
- 1993-06-28 IL IL106159A patent/IL106159A0/en unknown
- 1993-06-30 EP EP93916894A patent/EP0653941A1/en not_active Withdrawn
- 1993-06-30 CN CN93109549A patent/CN1092076A/en active Pending
- 1993-06-30 JP JP6502666A patent/JPH07508979A/en active Pending
- 1993-06-30 AU AU46600/93A patent/AU4660093A/en not_active Abandoned
- 1993-06-30 CA CA002139323A patent/CA2139323A1/en not_active Abandoned
- 1993-06-30 WO PCT/US1993/006254 patent/WO1994000145A1/en not_active Ceased
- 1993-06-30 HU HU9403840A patent/HUT71220A/en unknown
- 1993-06-30 FI FI946156A patent/FI946156A7/en unknown
- 1993-06-30 MX MX9303963A patent/MX9303963A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX9303963A (en) | 1995-01-31 |
| EP0653941A1 (en) | 1995-05-24 |
| HU9403840D0 (en) | 1995-02-28 |
| FI946156A0 (en) | 1994-12-29 |
| CA2139323A1 (en) | 1994-01-06 |
| FI946156L (en) | 1995-02-27 |
| AU4660093A (en) | 1994-01-24 |
| JPH07508979A (en) | 1995-10-05 |
| CN1092076A (en) | 1994-09-14 |
| FI946156A7 (en) | 1995-02-27 |
| IL106159A0 (en) | 1993-10-20 |
| WO1994000145A1 (en) | 1994-01-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DFA9 | Temporary protection cancelled due to abandonment |