HUT75111A - Use of pyridyl-,oxadiazole or thiadiazole derivatives for producing pharmaceutical compositions having effect - Google Patents

Use of pyridyl-,oxadiazole or thiadiazole derivatives for producing pharmaceutical compositions having effect

Info

Publication number
HUT75111A
HUT75111A HU9600364A HU9600364A HUT75111A HU T75111 A HUT75111 A HU T75111A HU 9600364 A HU9600364 A HU 9600364A HU 9600364 A HU9600364 A HU 9600364A HU T75111 A HUT75111 A HU T75111A
Authority
HU
Hungary
Prior art keywords
oxadiazole
pyridyl
effect
pharmaceutical compositions
thiadiazole derivatives
Prior art date
Application number
HU9600364A
Other languages
English (en)
Other versions
HU9600364D0 (en
HU221729B1 (hu
Inventor
Franklin Porter Bymaster
Harlan E Shannon
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of HU9600364D0 publication Critical patent/HU9600364D0/hu
Publication of HUT75111A publication Critical patent/HUT75111A/hu
Publication of HU221729B1 publication Critical patent/HU221729B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HU9600364A 1993-08-19 1994-08-15 Tiadiazolil-piridin-származékok alkalmazása antipszichotikus gyógyszerek előállítására HU221729B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10930093A 1993-08-19 1993-08-19
PCT/DK1994/000305 WO1995005174A1 (en) 1993-08-19 1994-08-15 Antipsychotic method

Publications (3)

Publication Number Publication Date
HU9600364D0 HU9600364D0 (en) 1996-04-29
HUT75111A true HUT75111A (en) 1997-04-28
HU221729B1 HU221729B1 (hu) 2002-12-28

Family

ID=22326932

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9600364A HU221729B1 (hu) 1993-08-19 1994-08-15 Tiadiazolil-piridin-származékok alkalmazása antipszichotikus gyógyszerek előállítására

Country Status (23)

Country Link
EP (1) EP0734259B1 (hu)
JP (1) JP3126736B2 (hu)
KR (1) KR100360575B1 (hu)
CN (1) CN1087936C (hu)
AT (1) ATE218864T1 (hu)
AU (1) AU701292B2 (hu)
CA (1) CA2169839C (hu)
CZ (1) CZ285030B6 (hu)
DE (1) DE69430816T2 (hu)
DK (1) DK0734259T3 (hu)
ES (1) ES2177581T3 (hu)
FI (2) FI960747A7 (hu)
HU (1) HU221729B1 (hu)
IL (1) IL110708A (hu)
NO (1) NO312706B1 (hu)
NZ (2) NZ336597A (hu)
PT (1) PT734259E (hu)
RU (1) RU2191580C2 (hu)
SG (1) SG55071A1 (hu)
TW (1) TW442284B (hu)
UA (1) UA63876C2 (hu)
WO (1) WO1995005174A1 (hu)
ZA (1) ZA946324B (hu)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605908A (en) * 1994-10-24 1997-02-25 Eli Lilly And Company Heterocyclic compounds and their use
US5998404A (en) * 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5672709A (en) * 1994-10-24 1997-09-30 Eli Lilly And Company Heterocyclic compounds and their preparation and use
JPH10508028A (ja) * 1994-10-31 1998-08-04 イーライ・リリー・アンド・カンパニー 不安を治療する方法
US5488056A (en) * 1994-10-31 1996-01-30 Eli Lilly And Company Method for treating anxiety
US5726193A (en) * 1994-10-31 1998-03-10 Eli Lilly And Company Method for treating anxiety
US5574028A (en) * 1994-10-31 1996-11-12 Eli Lilly And Company Method for treating anxiety
US5565475A (en) * 1994-11-08 1996-10-15 Muhlhauser; Mark A. Method of treating urinary bladder dysfunctions with 3-tetrahydropyridine derivatives
US5852037A (en) * 1995-11-13 1998-12-22 Eli Lilly And Company Method for treating anxiety
US5763457A (en) * 1995-11-13 1998-06-09 Eli Lilly And Company Method for treating anxiety
EP0821956A1 (en) * 1996-08-01 1998-02-04 Eli Lilly And Company Method for treating disruptive behavior disorders
US6117890A (en) * 1996-08-01 2000-09-12 Eli Lilly And Company Method for treating bipolar disorder
US6043258A (en) * 1996-08-01 2000-03-28 Eli Lilly And Company Method for treating disruptive behavior disorders with xanomeline
EP0821957A3 (en) * 1996-08-01 1998-04-22 Eli Lilly And Company Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (xanomeline) for treating substance abuse
EP0821958A3 (en) * 1996-08-01 1998-07-08 Eli Lilly And Company Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine (xanomeline) for treating excessive aggression
US6090829A (en) * 1996-08-01 2000-07-18 Eli Lilly And Company Method for treating excessive aggression
DK0821955T3 (da) * 1996-08-01 2002-03-18 Lilly Co Eli Anvendelse af 3-(4-heoxyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridin (xanomelin) til behandling af bipolar lidelse
EP0821954A1 (en) * 1996-08-01 1998-02-04 Eli Lilly And Company Method for treating mental retardation
EP0821959A3 (en) * 1996-08-01 1998-09-16 Eli Lilly And Company Use of 3-(4-hexyloxy-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine for treating nicotine withdrawal
EP1014974B1 (en) * 1997-05-29 2004-08-11 H. Lundbeck A/S Treatment of schizophrenia and psychosis
US6034108A (en) * 1997-07-28 2000-03-07 Eli Lilly And Company Method for treating mental retardation
PT3061821T (pt) 2009-07-22 2019-09-05 PureTech Health LLC Composições para tratamento de distúrbios melhorados por ativação de recetores muscarínicos
KR102408292B1 (ko) * 2018-09-28 2022-06-10 카루나 세러퓨틱스 인코포레이티드 무스카린성 수용체 활성화에 의해 개선된 장애의 치료를 위한 조성물 및 방법
US11534434B2 (en) 2019-11-15 2022-12-27 Karuna Therapeutics, Inc. Xanomeline derivatives and methods for treating neurological disorders
CN115974863B (zh) * 2021-10-14 2024-12-31 南京迈诺威医药科技有限公司 占诺美林衍生物的苹果酸盐、a晶型及其制备方法和用途
CN119161338B (zh) * 2024-11-25 2025-06-17 嘉兴安帝康生物科技有限公司 用作毒蕈碱受体激动剂的四氢吡啶衍生物及其在医药上的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
DK198390D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse
DK198490D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
DE69430816T2 (de) 2002-12-19
CZ42696A3 (en) 1996-11-13
JPH09501658A (ja) 1997-02-18
HU9600364D0 (en) 1996-04-29
CN1087936C (zh) 2002-07-24
KR960703592A (ko) 1996-08-31
NZ336597A (en) 2001-02-23
UA63876C2 (en) 2004-02-16
CZ285030B6 (cs) 1999-05-12
RU2191580C2 (ru) 2002-10-27
NO312706B1 (no) 2002-06-24
CN1133008A (zh) 1996-10-09
TW442284B (en) 2001-06-23
PT734259E (pt) 2002-11-29
EP0734259B1 (en) 2002-06-12
IL110708A0 (en) 1994-11-11
IL110708A (en) 1998-12-06
HU221729B1 (hu) 2002-12-28
JP3126736B2 (ja) 2001-01-22
FI960747A0 (fi) 1996-02-19
KR100360575B1 (ko) 2003-03-10
ATE218864T1 (de) 2002-06-15
SG55071A1 (en) 1998-12-21
FI20050461A7 (fi) 2005-04-29
DK0734259T3 (da) 2002-09-30
DE69430816D1 (de) 2002-07-18
AU701292B2 (en) 1999-01-21
FI960747L (fi) 1996-04-17
CA2169839C (en) 2002-06-11
WO1995005174A1 (en) 1995-02-23
FI960747A7 (fi) 1996-04-17
EP0734259A1 (en) 1996-10-02
FI20050461L (fi) 2005-04-29
AU7490294A (en) 1995-03-14
NO960619D0 (no) 1996-02-16
ZA946324B (en) 1996-02-19
NO960619L (no) 1996-04-18
NZ271311A (en) 1999-09-29
ES2177581T3 (es) 2002-12-16
CA2169839A1 (en) 1995-02-23

Similar Documents

Publication Publication Date Title
HUT75111A (en) Use of pyridyl-,oxadiazole or thiadiazole derivatives for producing pharmaceutical compositions having effect
GR3025762T3 (en) Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents.
EP0613883A4 (en) HYDROXAMIC ACID DERIVATIVE.
MX9603593A (es) Derivados de quinazolina.
AU7815791A (en) Heterocyclene derivatives
ES8707947A1 (es) Un procedimiento para la preparacion de acidos 3-hidroxifenoxialquilenheterociclilcarboxilicos.
TW368501B (en) 7-(2-aminoethyl)-benzothiazolones
TW243449B (hu)
AU1302388A (en) Method of treating anxiety with tetrahydrobenz(c,d)indole-6- carboxamides
NO994659L (no) Nye pyridinderivater og farmasöytiske preparater inneholdende slike
HUT63827A (en) Process for producing sulfonanilide derivatives and pharmaceutical compositions comprising same
ATE169217T1 (de) Verwendung von furanonderivaten zur vorbeugung oder behandlung von autoimmunkrankheiten
MX9803901A (es) Compuestos de di-terbutilfenol que contienen azufre utiles como agentes anti-inflamatorios.
EP0270046A3 (en) Pharmaceutical composition for treatment of cataract
TW222627B (hu)
AU2287499A (en) Azetidinecarboxamide derivatives for treating cns disorders
AU1855088A (en) Treating agent for heart failure
FR2378762A2 (fr) Amides aromatiques de composes heterocycliques et leur application en tant que medicament
NZ225800A (en) Optionally heterocyclically-substituted ethers and thio ethers and pharmaceutical compositions
AU2178099A (en) Azetidinecarboxamide derivatives for treating cns disorders
AU2013888A (en) Uricosuric composition

Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: ELI LILLY AND COMPANY, US

Free format text: FORMER OWNER(S): NOVO NORDISK A/S, DK

MM4A Lapse of definitive patent protection due to non-payment of fees