HUT77435A - Nucleotide Monomer Analogs Containing Amino Acids - Google Patents

Nucleotide Monomer Analogs Containing Amino Acids

Info

Publication number
HUT77435A
HUT77435A HU9702053A HU9702053A HUT77435A HU T77435 A HUT77435 A HU T77435A HU 9702053 A HU9702053 A HU 9702053A HU 9702053 A HU9702053 A HU 9702053A HU T77435 A HUT77435 A HU T77435A
Authority
HU
Hungary
Prior art keywords
amino acids
containing amino
nucleotide monomer
analogs containing
monomer analogs
Prior art date
Application number
HU9702053A
Other languages
Hungarian (hu)
Other versions
HU218086B (en
Inventor
Kandasamy Ramasamy
Wilfried Seifert
Guangyi Wang
Original Assignee
Icn Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icn Pharmaceuticals filed Critical Icn Pharmaceuticals
Publication of HUT77435A publication Critical patent/HUT77435A/en
Publication of HU218086B publication Critical patent/HU218086B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU9702053A 1994-11-02 1995-11-02 Nucleotide Monomer Analogs Containing Amino Acids HU218086B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33389594A 1994-11-02 1994-11-02

Publications (2)

Publication Number Publication Date
HUT77435A true HUT77435A (en) 1998-04-28
HU218086B HU218086B (en) 2000-05-28

Family

ID=23304698

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9702053A HU218086B (en) 1994-11-02 1995-11-02 Nucleotide Monomer Analogs Containing Amino Acids

Country Status (14)

Country Link
EP (1) EP0789707A4 (en)
JP (1) JPH10508312A (en)
KR (1) KR100393336B1 (en)
CN (1) CN1171112A (en)
AU (1) AU693622B2 (en)
CA (1) CA2202274A1 (en)
HU (1) HU218086B (en)
MX (1) MX9703188A (en)
PL (1) PL185852B1 (en)
RU (1) RU2154638C2 (en)
SI (1) SI9520112A (en)
SK (1) SK2694U (en)
UA (1) UA48150C2 (en)
WO (1) WO1996014330A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840879A (en) * 1996-12-06 1998-11-24 Wang; Edge R. Reagents and solid supports for improved synthesis and labeling of polynucleotides
EP1240174A2 (en) * 1999-12-22 2002-09-18 Metabasis Therapeutics, Inc. Novel bisamidate phosphonate prodrugs
EP1386155A4 (en) * 2001-04-10 2006-05-10 Univ Leland Stanford Junior Therapeutic and diagnostic uses of antibody specificity profiles
DK2207779T3 (en) * 2007-11-15 2014-07-14 Sarepta Therapeutics Inc Process for the Synthesis of Morpholine Oligomers
US8865898B2 (en) 2010-11-30 2014-10-21 Japan Science And Technology Agency Nucleoside analog or salt thereof, oligonucleotide analog, gene expression inhibitor, and nucleic-acid probe for detecting gene
RU2460721C1 (en) * 2011-02-25 2012-09-10 Учреждение Российской академии наук Институт химической биологии и фундаментальной медицины Сибирского отделения РАН (ИХБФМ СО РАН) Method of producing amidophosphite monomer of achiral non-nucleotide insert for modifying oligonucleotides
DE102014007158A1 (en) * 2014-05-16 2015-11-19 Ugichem Gmbh New peptide-nucleic acid monomers and oligomers
EP3643706B1 (en) 2017-06-16 2023-11-15 Eisai R&D Management Co., Ltd. Modified nucleic acid monomers and oligonucleic acid analogues, with high biological stability and target gene silencing activity, for use in therapy and diagnosis of cancer and viral diseases
CN113956183B (en) * 2021-10-28 2023-06-20 成都市科隆化学品有限公司 Boc-Ser (Bzl) -OH and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986005519A1 (en) * 1985-03-15 1986-09-25 James Summerton Polynucleotide assay reagent and method
DK51092D0 (en) * 1991-05-24 1992-04-15 Ole Buchardt OLIGONUCLEOTIDE ANALOGUE DESCRIBED BY PEN, MONOMERIC SYNTHONES AND PROCEDURES FOR PREPARING THEREOF, AND APPLICATIONS THEREOF

Also Published As

Publication number Publication date
RU2154638C2 (en) 2000-08-20
UA48150C2 (en) 2002-08-15
HU218086B (en) 2000-05-28
EP0789707A4 (en) 1999-02-24
PL185852B1 (en) 2003-08-29
SI9520112A (en) 1998-08-31
EP0789707A1 (en) 1997-08-20
JPH10508312A (en) 1998-08-18
AU4234196A (en) 1996-05-31
KR970707144A (en) 1997-12-01
MX9703188A (en) 1997-12-31
WO1996014330A1 (en) 1996-05-17
AU693622B2 (en) 1998-07-02
SK2694U (en) 2000-11-07
PL320084A1 (en) 1997-09-15
KR100393336B1 (en) 2003-12-24
CA2202274A1 (en) 1996-05-17
CN1171112A (en) 1998-01-21

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee
HMM4 Cancellation of final prot. due to non-payment of fee