ID22873A - HETEROSICLIC COMPOUNDS AND ITS USE TO INITIATE B-AMYLOID PEPTIDES - Google Patents
HETEROSICLIC COMPOUNDS AND ITS USE TO INITIATE B-AMYLOID PEPTIDESInfo
- Publication number
- ID22873A ID22873A IDW990811A ID990811A ID22873A ID 22873 A ID22873 A ID 22873A ID W990811 A IDW990811 A ID W990811A ID 990811 A ID990811 A ID 990811A ID 22873 A ID22873 A ID 22873A
- Authority
- ID
- Indonesia
- Prior art keywords
- heterosiclic
- initiate
- compounds
- amyloid peptides
- amyloid
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80826397A | 1997-02-28 | 1997-02-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID22873A true ID22873A (en) | 1999-12-16 |
Family
ID=25198310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW990811A ID22873A (en) | 1997-02-28 | 1998-02-27 | HETEROSICLIC COMPOUNDS AND ITS USE TO INITIATE B-AMYLOID PEPTIDES |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0968198A1 (en) |
| JP (1) | JP2001513107A (en) |
| KR (1) | KR20000075767A (en) |
| CN (1) | CN1253554A (en) |
| AR (1) | AR011164A1 (en) |
| AU (1) | AU6662298A (en) |
| BR (1) | BR9807876A (en) |
| CA (1) | CA2278674A1 (en) |
| CO (1) | CO4920244A1 (en) |
| EA (1) | EA199900778A1 (en) |
| HR (1) | HRP980093A2 (en) |
| HU (1) | HUP0001293A3 (en) |
| ID (1) | ID22873A (en) |
| IL (1) | IL130851A0 (en) |
| NO (1) | NO994016L (en) |
| NZ (1) | NZ336613A (en) |
| PE (1) | PE59399A1 (en) |
| PL (1) | PL335424A1 (en) |
| TR (1) | TR199902071T2 (en) |
| WO (1) | WO1998038177A1 (en) |
| YU (1) | YU7998A (en) |
| ZA (1) | ZA981627B (en) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6635632B1 (en) | 1996-12-23 | 2003-10-21 | Athena Neurosciences, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| IL135564A0 (en) * | 1997-12-22 | 2001-05-20 | Elan Pharm Inc | POLYCYCLIC α-AMINO-ɛ-CAPROLACTAMS AND RELATED COMPOUNDS |
| US6958330B1 (en) | 1998-06-22 | 2005-10-25 | Elan Pharmaceuticals, Inc. | Polycyclic α-amino-ε-caprolactams and related compounds |
| JP2002518481A (en) * | 1998-06-22 | 2002-06-25 | エラン ファーマシューティカルズ，インコーポレイテッド | Compounds for inhibiting the release of β-amyloid peptide and / or its synthesis |
| US6509331B1 (en) | 1998-06-22 | 2003-01-21 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6774125B2 (en) | 1998-06-22 | 2004-08-10 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6569851B1 (en) | 1998-06-22 | 2003-05-27 | Elan Pharmaceutials, Inc. | Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6552013B1 (en) | 1998-06-22 | 2003-04-22 | Elan Pharmaceuticals, Inc. | Deoxyamino acid compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6528505B1 (en) | 1998-06-22 | 2003-03-04 | Elan Pharmaceuticals, Inc. | Cyclic amino acid compounds pharmaceutical compositions comprising same and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
| US6737038B1 (en) | 1998-11-12 | 2004-05-18 | Bristol-Myers Squibb Company | Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging |
| EP1159273A1 (en) | 1999-03-02 | 2001-12-05 | Boehringer Ingelheim Pharmaceuticals Inc. | Compounds useful as reversible inhibitors of cathepsin s |
| US7160880B1 (en) | 1999-05-14 | 2007-01-09 | Cenes Limited | Short-acting benzodiazepines |
| GB9911803D0 (en) * | 1999-05-20 | 1999-07-21 | Merck Sharp & Dohme | Therapeutic combination |
| MXPA02001340A (en) * | 1999-08-05 | 2004-07-16 | Prescient Neuropharma Inc | Novel 1,4-benzodiazepine compounds and derivatives thereof. |
| US6420364B1 (en) | 1999-09-13 | 2002-07-16 | Boehringer Ingelheim Pharmaceuticals, Inc. | Compound useful as reversible inhibitors of cysteine proteases |
| US6878363B2 (en) | 2000-05-17 | 2005-04-12 | Bristol-Myers Squibb Pharma Company | Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging |
| CN1386118A (en) | 2000-06-01 | 2002-12-18 | 布里斯托尔-迈尔斯斯奎布药品公司 | Lactams substituted by cyclic succinates as inhibitors of A beta protein production |
| DE10029077A1 (en) * | 2000-06-13 | 2001-12-20 | Bayer Ag | New heterocyclic-substituted thiazole derivatives, useful as total or selective herbicides, insecticides, acaricides, nematocides, ectoparasiticides or antifouling agents |
| US6432944B1 (en) | 2000-07-06 | 2002-08-13 | Bristol-Myers Squibb Company | Benzodiazepinone β-amyloid inhibitors: arylacetamidoalanyl derivatives |
| FR2840899B1 (en) * | 2002-06-12 | 2005-02-25 | Sanofi Synthelabo | ACYLAMINOTHIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THERAPEUTICS |
| AR039059A1 (en) | 2001-08-06 | 2005-02-09 | Sanofi Aventis | COMPOUND DERIVED FROM ACILAMINOTIAZOL, ITS USE, PROCEDURES TO PREPARE IT, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, AND INTERMEDIARY COMPOUNDS |
| CA2486350A1 (en) | 2002-06-05 | 2003-12-24 | Kaneka Corporation | Process for producing optically active .alpha.-methylcysteine derivative |
| CA2580767A1 (en) | 2004-09-17 | 2006-03-30 | Whitehead Institute For Biomedical Research | Compounds, compositions and methods of inhibiting alpha-synuclein toxicity |
| US7449486B2 (en) | 2004-10-19 | 2008-11-11 | Array Biopharma Inc. | Mitotic kinesin inhibitors and methods of use thereof |
| UA95907C2 (en) | 2005-05-02 | 2011-09-26 | Эррей Биофарма Инк. | Mitotic kinesin inhibitors and methods of use thereof |
| EP1757290A1 (en) | 2005-08-16 | 2007-02-28 | Zentaris GmbH | Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors |
| JP2010505870A (en) | 2006-10-03 | 2010-02-25 | アレイ バイオファーマ、インコーポレイテッド | Oxadiazole derivatives and thiadiazole derivatives as mitotic kinesin inhibitors and methods for their use |
| JP5781928B2 (en) * | 2008-07-16 | 2015-09-24 | ビトップ アーゲーｂｉｔｏｐ ＡＧ | Synthesis of cyclic amidine |
| US9133123B2 (en) | 2010-04-23 | 2015-09-15 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
| AR081626A1 (en) | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | AMINO-PYRIDAZINIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND USE OF THE SAME TO TREAT CARDIAC AND SKELETIC MUSCULAR DISORDERS |
| AR081331A1 (en) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | AMINO- PYRIMIDINES COMPOSITIONS OF THE SAME AND METHODS FOR THE USE OF THE SAME |
| EP2431035A1 (en) | 2010-09-16 | 2012-03-21 | Æterna Zentaris GmbH | Novel Triazole Derivatives with Improved Receptor Activity and Bioavailability Properties as Ghrelin Antagonists of Growth Hormone Secretagogue Receptors |
| US8759380B2 (en) | 2011-04-22 | 2014-06-24 | Cytokinetics, Inc. | Certain heterocycles, compositions thereof, and methods for their use |
| US8809372B2 (en) | 2011-09-30 | 2014-08-19 | Asana Biosciences, Llc | Pyridine derivatives |
| CN103435549A (en) * | 2013-08-14 | 2013-12-11 | 无锡惠飞生物医药技术有限公司 | 5-methyl-7-amino-5H,7H-dibenzo[b,d]azepin-6-ketone preparation method |
| CN105646208B (en) * | 2016-02-24 | 2018-10-16 | 潍坊晶润化工股份有限公司 | The preparation method of methyl pyruvate |
| CN119819277B (en) * | 2025-03-17 | 2025-05-27 | 昆明医科大学 | A BINAM-based β-cyclodextrin derivative chiral stationary phase and its preparation method and application |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2221684A1 (en) * | 1995-06-06 | 1996-12-12 | Athena Neurosciences, Inc. | Novel cathepsin and methods and compositions for inhibition thereof |
-
1998
- 1998-02-24 AR ARP980100812A patent/AR011164A1/en unknown
- 1998-02-24 HR HR08/808,236A patent/HRP980093A2/en not_active Application Discontinuation
- 1998-02-26 ZA ZA9801627A patent/ZA981627B/en unknown
- 1998-02-27 PE PE1998000144A patent/PE59399A1/en not_active Application Discontinuation
- 1998-02-27 CA CA002278674A patent/CA2278674A1/en not_active Abandoned
- 1998-02-27 NZ NZ336613A patent/NZ336613A/en unknown
- 1998-02-27 EP EP98908637A patent/EP0968198A1/en not_active Withdrawn
- 1998-02-27 HU HU0001293A patent/HUP0001293A3/en unknown
- 1998-02-27 BR BR9807876-3A patent/BR9807876A/en not_active IP Right Cessation
- 1998-02-27 YU YU7998A patent/YU7998A/en unknown
- 1998-02-27 IL IL13085198A patent/IL130851A0/en unknown
- 1998-02-27 CN CN98802875A patent/CN1253554A/en active Pending
- 1998-02-27 KR KR1019997007839A patent/KR20000075767A/en not_active Withdrawn
- 1998-02-27 EA EA199900778A patent/EA199900778A1/en unknown
- 1998-02-27 CO CO98010854A patent/CO4920244A1/en unknown
- 1998-02-27 JP JP53773298A patent/JP2001513107A/en active Pending
- 1998-02-27 WO PCT/US1998/003373 patent/WO1998038177A1/en not_active Ceased
- 1998-02-27 PL PL98335424A patent/PL335424A1/en unknown
- 1998-02-27 TR TR1999/02071T patent/TR199902071T2/en unknown
- 1998-02-27 ID IDW990811A patent/ID22873A/en unknown
- 1998-02-27 AU AU66622/98A patent/AU6662298A/en not_active Abandoned
-
1999
- 1999-08-19 NO NO994016A patent/NO994016L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL335424A1 (en) | 2000-04-25 |
| BR9807876A (en) | 2000-02-29 |
| CO4920244A1 (en) | 2000-05-29 |
| KR20000075767A (en) | 2000-12-26 |
| WO1998038177A1 (en) | 1998-09-03 |
| HUP0001293A1 (en) | 2000-08-28 |
| CN1253554A (en) | 2000-05-17 |
| EA199900778A1 (en) | 2000-04-24 |
| JP2001513107A (en) | 2001-08-28 |
| IL130851A0 (en) | 2001-01-28 |
| CA2278674A1 (en) | 1998-09-03 |
| TR199902071T2 (en) | 2000-01-21 |
| HRP980093A2 (en) | 1998-12-31 |
| AU6662298A (en) | 1998-09-18 |
| YU7998A (en) | 2002-06-19 |
| HUP0001293A3 (en) | 2000-09-28 |
| NO994016L (en) | 1999-10-18 |
| EP0968198A1 (en) | 2000-01-05 |
| NZ336613A (en) | 2001-10-26 |
| AR011164A1 (en) | 2000-08-02 |
| ZA981627B (en) | 1999-10-05 |
| PE59399A1 (en) | 1999-06-21 |
| NO994016D0 (en) | 1999-08-19 |
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