ID23038A - Senyawa-senyawa guanidinilamino heterosiklus yang berguna sebagai agonis adrenoseptor alfa-2 - Google Patents

Senyawa-senyawa guanidinilamino heterosiklus yang berguna sebagai agonis adrenoseptor alfa-2

Info

Publication number: ID23038A
Authority: ID; Indonesia
Prior art keywords: heterosiclus; guanidinilamino; adrenoseptor; alfa; agonists
Prior art date: 1996-11-25

Application number

IDW990404D

Other languages

English (en)

Indonesian (id)

Inventor

Thomas Lee Cupps

Shopie Eva Bogdan

Raymond Todd Henry

Russell James Sheldon

William Lee Seibel

Jeffrey Joseph Ares

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-25

Filing date

1997-11-21

Publication date

2000-01-06

1997-11-21 Application filed by Procter & Gamble filed Critical Procter & Gamble

2000-01-06 Publication of ID23038A publication Critical patent/ID23038A/id

Links

239000000556 agonist Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Otolaryngology (AREA)
Inorganic Chemistry (AREA)
Pulmonology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Addiction (AREA)
Heart & Thoracic Surgery (AREA)
Zoology (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Cardiology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Indole Compounds (AREA)
Quinoline Compounds (AREA)

IDW990404D 1996-11-25 1997-11-21 Senyawa-senyawa guanidinilamino heterosiklus yang berguna sebagai agonis adrenoseptor alfa-2 ID23038A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3183396P	1996-11-25	1996-11-25

Publications (1)

Publication Number	Publication Date
ID23038A true ID23038A (id)	2000-01-06

Family

ID=21861650

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW990404D ID23038A (id)	1996-11-25	1997-11-21	Senyawa-senyawa guanidinilamino heterosiklus yang berguna sebagai agonis adrenoseptor alfa-2

Country Status (23)

Country	Link
EP (1)	EP0944601B1 (de)
JP (1)	JP2001504839A (de)
KR (1)	KR20000069130A (de)
CN (1)	CN1163486C (de)
AR (1)	AR009144A1 (de)
AT (1)	ATE232518T1 (de)
AU (1)	AU729421B2 (de)
BR (1)	BR9714362A (de)
CA (1)	CA2272098C (de)
CZ (1)	CZ183799A3 (de)
DE (1)	DE69719068T2 (de)
DK (1)	DK0944601T3 (de)
ES (1)	ES2192703T3 (de)
HU (1)	HUP0000479A3 (de)
ID (1)	ID23038A (de)
IL (1)	IL130023A0 (de)
NO (1)	NO313286B1 (de)
NZ (1)	NZ335859A (de)
PE (1)	PE16499A1 (de)
SK (1)	SK68599A3 (de)
TR (1)	TR199901467T2 (de)
WO (1)	WO1998023591A1 (de)
ZA (1)	ZA9710575B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6172095B1 (en)	1996-11-25	2001-01-09	The Procter & Gamble Company	Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
US6306877B1 (en)	1999-08-09	2001-10-23	The Procter & Gamble Co.	Guanidinylamino heterocycle compounds useful as alpha-2 adrenoceptor agonists
NL1009376C1 (nl) *	1998-06-11	1998-07-06	Boardwalk Ag	Datasysteem voor het verschaffen van relatiepatronen tussen personen.
US6294553B1 (en) *	2000-02-15	2001-09-25	Allergan Sales, Inc.	Method for treating ocular pain
US8555875B2 (en)	2008-12-23	2013-10-15	Map Pharmaceuticals, Inc.	Inhalation devices and related methods for administration of sedative hypnotic compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5478858A (en) *	1993-12-17	1995-12-26	The Procter & Gamble Company	5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists
US5576437A (en) *	1993-12-17	1996-11-19	The Procter & Gamble Company	7-(2-imidazolnylamino) quinoline compounds useful as alpha-2 adrenoceptor agonists

1997
- 1997-11-21 JP JP52468598A patent/JP2001504839A/ja active Pending
- 1997-11-21 TR TR1999/01467T patent/TR199901467T2/xx unknown
- 1997-11-21 CA CA002272098A patent/CA2272098C/en not_active Expired - Fee Related
- 1997-11-21 IL IL13002397A patent/IL130023A0/xx unknown
- 1997-11-21 CN CNB971810753A patent/CN1163486C/zh not_active Expired - Fee Related
- 1997-11-21 BR BR9714362A patent/BR9714362A/pt not_active IP Right Cessation
- 1997-11-21 HU HU0000479A patent/HUP0000479A3/hu unknown
- 1997-11-21 CZ CZ991837A patent/CZ183799A3/cs unknown
- 1997-11-21 KR KR1019997004618A patent/KR20000069130A/ko not_active Ceased
- 1997-11-21 ES ES97949399T patent/ES2192703T3/es not_active Expired - Lifetime
- 1997-11-21 AU AU74025/98A patent/AU729421B2/en not_active Ceased
- 1997-11-21 SK SK685-99A patent/SK68599A3/sk unknown
- 1997-11-21 DE DE69719068T patent/DE69719068T2/de not_active Expired - Fee Related
- 1997-11-21 NZ NZ335859A patent/NZ335859A/xx unknown
- 1997-11-21 DK DK97949399T patent/DK0944601T3/da active
- 1997-11-21 AT AT97949399T patent/ATE232518T1/de not_active IP Right Cessation
- 1997-11-21 WO PCT/US1997/020550 patent/WO1998023591A1/en not_active Ceased
- 1997-11-21 EP EP97949399A patent/EP0944601B1/de not_active Expired - Lifetime
- 1997-11-21 ID IDW990404D patent/ID23038A/id unknown
- 1997-11-25 AR ARP970105528A patent/AR009144A1/es unknown
- 1997-11-25 ZA ZA9710575A patent/ZA9710575B/xx unknown
- 1997-11-25 PE PE1997001066A patent/PE16499A1/es not_active Application Discontinuation
1999
- 1999-05-25 NO NO19992503A patent/NO313286B1/no unknown

Also Published As

Publication number	Publication date
HUP0000479A2 (hu)	2000-09-28
PE16499A1 (es)	1999-03-12
IL130023A0 (en)	2000-02-29
ATE232518T1 (de)	2003-02-15
DK0944601T3 (da)	2003-06-10
CA2272098A1 (en)	1998-06-04
WO1998023591A1 (en)	1998-06-04
AU729421B2 (en)	2001-02-01
CZ183799A3 (cs)	1999-09-15
DE69719068D1 (de)	2003-03-20
AR009144A1 (es)	2000-03-08
AU7402598A (en)	1998-06-22
ZA9710575B (en)	1998-06-10
KR20000069130A (ko)	2000-11-25
CN1163486C (zh)	2004-08-25
TR199901467T2 (xx)	1999-10-21
NO313286B1 (no)	2002-09-09
JP2001504839A (ja)	2001-04-10
EP0944601B1 (de)	2003-02-12
BR9714362A (pt)	2000-03-21
NO992503D0 (no)	1999-05-25
CA2272098C (en)	2003-11-11
NZ335859A (en)	2000-11-24
DE69719068T2 (de)	2003-11-27
EP0944601A1 (de)	1999-09-29
NO992503L (no)	1999-07-23
HUP0000479A3 (en)	2002-06-28
ES2192703T3 (es)	2003-10-16
CN1242001A (zh)	2000-01-19
SK68599A3 (en)	2000-06-12

Publication	Publication Date	Title
ID22812A (id)	1999-12-09	Senyawa 2-imidazolinilaminoindol yang berguna sebagai agonis adrenoseptor alfa-2
ID23857A (id)	2000-05-25	Senyawa-senyawa guanidinil heterosiklik yang berguna sebagai agonis adrenoceptor alfa-2
ID24836A (id)	2000-08-24	Agonis prostaglandin
ID29021A (id)	2001-07-26	Komposisi galantamina pelepasan terkontrol
FI963510L (fi)	1996-09-06	Isoksatsoliiniyhdisteitä TNF:n vapautumisen inhibiittoreina
PT945132E (pt)	2004-08-31	Composicao de ibuprofeno
BR9702049A (pt)	1998-01-13	Uso de composiç es compreendendo composfos biologicamente eficazes estabilizados
PT892640E (pt)	2004-06-30	Composicoes farmaceuticas de micofenolato entericamente revestidas
ID24372A (id)	2000-07-13	SENYAWA-SENYAWA 4-AMINO-TIAZOL-2-IL SEBAGAI PENGHAMBAT-PENGHAMBAT CDKs
ID18829A (id)	1998-05-14	Komposisi sabun yang dicetak
BR9509200A (pt)	1997-12-30	Composição de matéria
PT907364E (pt)	2002-12-31	Composicao farmaceutica de libertacao sustida
ID22764A (id)	1999-12-09	Komposisi pembersih abrasif-semprot
EE9800298A (et)	1999-02-15	Farmatseutiliselt kasulikud ühendid
ID22060A (id)	1999-08-26	Senyawa-senyawa 2-imidazolinilaminobenzoksazol berguna sebagai agonis adrenoseptor
ID17561A (id)	1998-01-08	Komposisi untuk pemakaian luar
ID18832A (id)	1998-05-14	Komposisi insektisida
ID16154A (id)	1997-09-04	Komposisi monomer yang distabilisasi
ID24677A (id)	2000-07-27	Kombinasi senyawa aktif fungisidal
ID16838A (id)	1997-11-13	Komposisi dekafluoropentana
ID22676A (id)	1999-12-09	Senyawa-senyawa 2-imidalinilaminoindazol yang berguna sebagai agonis adrenoseptor alfa-2
ID17419A (id)	1997-12-24	Komposisi dekafluoropentana
ID24132A (id)	2000-07-06	Komposisi pembersih yang bersifat abrasif
ID24081A (id)	2000-07-06	Senyawa-senyawa 5-(2-imidazolinilamino) benzimidazol yang berguna sebagai agonis-agonis alfa-2-adrenoseptor
ID23774A (id)	2000-05-11	Komposisi insektisida