ID24845A - Prostaglandin tetrahidro tersubstitusi c16-c20 aromatik yang berguna sebagai agonis fp - Google Patents

Prostaglandin tetrahidro tersubstitusi c16-c20 aromatik yang berguna sebagai agonis fp

Info

Publication number
ID24845A
ID24845A IDW20000641A ID20000641A ID24845A ID 24845 A ID24845 A ID 24845A ID W20000641 A IDW20000641 A ID W20000641A ID 20000641 A ID20000641 A ID 20000641A ID 24845 A ID24845 A ID 24845A
Authority
ID
Indonesia
Prior art keywords
prostaglandin
agonist
aromatic
substituted
substituted prostaglandin
Prior art date
Application number
IDW20000641A
Other languages
English (en)
Indonesian (id)
Inventor
M A Delong
J A Wos
J S Amburgey
Biswanath De
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of ID24845A publication Critical patent/ID24845A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW20000641A 1997-09-09 1998-09-04 Prostaglandin tetrahidro tersubstitusi c16-c20 aromatik yang berguna sebagai agonis fp ID24845A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5825297P 1997-09-09 1997-09-09

Publications (1)

Publication Number Publication Date
ID24845A true ID24845A (id) 2000-08-24

Family

ID=22015635

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000641A ID24845A (id) 1997-09-09 1998-09-04 Prostaglandin tetrahidro tersubstitusi c16-c20 aromatik yang berguna sebagai agonis fp

Country Status (24)

Country Link
US (1) US6048895A (fr)
EP (1) EP1012137B1 (fr)
JP (2) JP4619531B2 (fr)
KR (1) KR20010023838A (fr)
CN (1) CN1269784A (fr)
AR (1) AR017078A1 (fr)
AT (1) ATE227266T1 (fr)
AU (1) AU731032B2 (fr)
BR (1) BR9812631A (fr)
CA (1) CA2303801C (fr)
CO (1) CO4970733A1 (fr)
DE (1) DE69809268T2 (fr)
DK (1) DK1012137T3 (fr)
HU (1) HUP0004427A3 (fr)
ID (1) ID24845A (fr)
IL (1) IL134840A0 (fr)
NO (1) NO20001139L (fr)
NZ (1) NZ503738A (fr)
PE (1) PE123099A1 (fr)
PL (1) PL339221A1 (fr)
SK (1) SK3382000A3 (fr)
TR (1) TR200000673T2 (fr)
WO (1) WO1999012898A1 (fr)
ZA (1) ZA988232B (fr)

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EP0930296B2 (fr) * 1996-09-17 2005-11-02 Asahi Glass Company Ltd. Derives de prostaglandine fluores et medicaments
SK3382000A3 (en) * 1997-09-09 2000-10-09 Procter & Gamble A compound having structure of aromatic substituted prostaglandins and its use for the treatment of bone disorders
CA2364948C (fr) * 1999-03-05 2011-04-26 Duke University Analogues de prostaglandines c16 fp selectives insaturees
US6894175B1 (en) 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
IL147771A0 (en) * 1999-08-04 2002-08-14 Procter & Gamble Novel 2-decarboxy-2-phosphinico prostaglandin f analogs
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020037914A1 (en) * 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins
KR100437873B1 (ko) * 2001-05-08 2004-06-26 연성정밀화학(주) 프로스타글란딘 유도체의 제조방법 및 그의 입체특이적출발물질
US6905827B2 (en) * 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US20060135609A1 (en) * 2004-10-21 2006-06-22 Duke University Ophthamological drugs
US20070254920A1 (en) * 2006-04-26 2007-11-01 Aerie Pharmaceuticals, Inc. Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use
US8455513B2 (en) 2007-01-10 2013-06-04 Aerie Pharmaceuticals, Inc. 6-aminoisoquinoline compounds
EP2214482A4 (fr) 2007-10-31 2011-08-24 Pamela Lipkin Compositions d'analogues de prostaglandine et procédés de traitement d'états épithéliaux
WO2010039535A1 (fr) * 2008-09-23 2010-04-08 Meta Cosmetics, Llc Compositions et procédés de traitement d'états en relation avec l'épithélium
US8450344B2 (en) 2008-07-25 2013-05-28 Aerie Pharmaceuticals, Inc. Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
JP2012507552A (ja) 2008-10-29 2012-03-29 アエリエ・ファーマシューティカルズ・インコーポレーテッド プロスタグラジンのアミノ酸塩
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
EP3828172A1 (fr) 2009-05-01 2021-06-02 Aerie Pharmaceuticals, Inc. Inhibiteurs à double mecanisme pour le traitement d'une maladie
CN103864653A (zh) * 2012-12-10 2014-06-18 韩冰 一类降低眼压的化合物及其用途
US20140275160A1 (en) 2013-03-15 2014-09-18 Aerie Pharmaceuticals, Inc. Combination therapy
US9643927B1 (en) 2015-11-17 2017-05-09 Aerie Pharmaceuticals, Inc. Process for the preparation of kinase inhibitors and intermediates thereof
CN109640966A (zh) 2016-08-31 2019-04-16 爱瑞制药公司 眼用组合物
WO2018183911A1 (fr) 2017-03-31 2018-10-04 Aerie Pharmaceuticals, Inc. Composés d'amide aryl cyclopropyl-amino-isoquinolinyl
US11427563B2 (en) 2018-09-14 2022-08-30 Aerie Pharmaceuticals, Inc. Aryl cyclopropyl-amino-isoquinolinyl amide compounds

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US3776938A (en) * 1958-05-28 1973-12-04 S Bergstrom Dihydro-pge1
US4011262A (en) * 1972-07-13 1977-03-08 Pfizer Inc. 13,14-Dihydro-15-substituted-ω-pentanorprostaglandins of the two series
DD118856A5 (fr) * 1972-11-08 1976-03-20
US4024179A (en) * 1972-11-08 1977-05-17 Pfizer Inc. Substituted ω-pentanorprostaglandins
IL50310A (en) * 1972-11-08 1977-08-31 Pfizer Dimethyl ketophosphonates
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WO1998021180A1 (fr) * 1995-06-07 1998-05-22 Alcon Laboratories, Inc. Prostaglandines aryle ou heteroaryle a conformation rigide utilisees dans le traitement des glaucomes
WO1997023225A1 (fr) * 1995-12-22 1997-07-03 Alcon Laboratories, Inc. Combinaisons de prostaglandines de type dp et fp destinees a abaisser la pression intraoculaire
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US6242485B1 (en) * 1996-06-10 2001-06-05 R-Tech Ueno Endothelin antagonist
EP0930296B2 (fr) * 1996-09-17 2005-11-02 Asahi Glass Company Ltd. Derives de prostaglandine fluores et medicaments
US6353014B1 (en) * 1996-11-12 2002-03-05 Alcon Laboratories, Inc. 15-ketal postaglandins for the treatment of glaucoma or ocular hypertension
WO1998020880A2 (fr) * 1996-11-12 1998-05-22 Alcon Laboratories, Inc. 11-halo prostaglandines destinees au traitement du glaucome ou de l'hypertension oculaire
CA2293325C (fr) * 1997-05-09 2008-09-02 The Mount Sinai School Of Medicine Of The City University Of New York Traitement du glaucome a base de 8-iso-prostaglandines
SK3382000A3 (en) * 1997-09-09 2000-10-09 Procter & Gamble A compound having structure of aromatic substituted prostaglandins and its use for the treatment of bone disorders

Also Published As

Publication number Publication date
EP1012137A1 (fr) 2000-06-28
DE69809268D1 (de) 2002-12-12
CA2303801C (fr) 2005-05-10
NO20001139D0 (no) 2000-03-06
ZA988232B (en) 1999-03-09
DE69809268T2 (de) 2003-08-28
TR200000673T2 (tr) 2000-11-21
WO1999012898A1 (fr) 1999-03-18
HUP0004427A3 (en) 2001-09-28
JP5330324B2 (ja) 2013-10-30
ATE227266T1 (de) 2002-11-15
AU731032B2 (en) 2001-03-22
EP1012137B1 (fr) 2002-11-06
SK3382000A3 (en) 2000-10-09
PE123099A1 (es) 2000-02-02
JP4619531B2 (ja) 2011-01-26
BR9812631A (pt) 2000-08-22
AU9224098A (en) 1999-03-29
IL134840A0 (en) 2001-05-20
AR017078A1 (es) 2001-08-22
JP2010254705A (ja) 2010-11-11
PL339221A1 (en) 2000-12-04
DK1012137T3 (da) 2003-03-10
HUP0004427A2 (hu) 2001-05-28
CA2303801A1 (fr) 1999-03-18
CN1269784A (zh) 2000-10-11
US6048895A (en) 2000-04-11
NZ503738A (en) 2001-05-25
KR20010023838A (ko) 2001-03-26
JP2001515885A (ja) 2001-09-25
NO20001139L (no) 2000-05-04
CO4970733A1 (es) 2000-11-07

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